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Human Polyclonal YWHAB Primary Antibody for IHC (p), WB - ABIN1882154
Komori, Ishizawa, Arai, Hirose, Mizutani, Oda: Immunoexpression of 14-3-3 proteins in glial cytoplasmic inclusions of multiple system atrophy. in Acta neuropathologica 2003
Show all 7 Pubmed References
Cow (Bovine) Polyclonal YWHAB Primary Antibody for IHC (p), ELISA - ABIN2477181
Crandall, Heesch: Baroreflex control of sympathetic outflow in pregnant rats: effects of captopril. in The American journal of physiology 1990
Show all 4 Pubmed References
Human Polyclonal YWHAB Primary Antibody for ICC, IF - ABIN4276654
ODwyer, Ralton, OShea, Murray: The proteomics of colorectal cancer: identification of a protein signature associated with prognosis. in PLoS ONE 2011
Data show that 14-3-3beta protein augmented the expression of matrix metalloproteinasea MMP2 (show MMP2 Antibodies) and MMP9 (show MMP9 Antibodies) through PI3 kinase (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) protein/NF-kappaappa B pathway, thereby enhancing the invasiveness of hepatocellular carcinoma (HCC (show FAM126A Antibodies)) cells.
These findings indicate that 14-3-3beta and gamma are novel PPARgamma2 (show PPARG Antibodies) regulators and are involved in hepatic lipid metabolism. 14-3-3b and gamma can be therapeutic target molecules to treat non-alcoholic fatty liver disease.
miR (show MLXIP Antibodies)-152 controls both the expression of 14-3-3beta and HLA-G (show HLAG Antibodies) and exerts a dual role in tumor cells by both altering the immunogenicity and the tumorigenicity
Data suggest that serum 14-3-3beta concentrations may constitute a useful marker for blood brain barrier damage severity and follow up in patients with eosinophilic meningitis caused by Angiostrongylus cantonensis.
Using gene reporter assays, we show that promoter variations in 11 intrinsic apoptosis genes, including ADPRT (show PARP1 Antibodies), APAF1 (show APAF1 Antibodies), BCL2 (show BCL2 Antibodies), BAD, BID (show BID Antibodies), MCL1 (show MCL1 Antibodies), BIRC4 (show XIAP Antibodies), BCL2L1 (show BCL2L1 Antibodies), ENDOG (show ENDOG Antibodies), YWHAB, and YWHAQ (show YWHAQ Antibodies), influence promoter activity in an allele-specific manner.
Crystal structure of Myo1c (show MYO1C Antibodies)/14-3-3beta complex, which has been implicated in the exocytosis of glucose transporter 4 storage vesicles during insulin (show INS Antibodies)-stimulated glucose uptake.
Data identified three classes of 14-3-3 (show YWHAQ Antibodies) targets that all have two binding sites, but displayed synergistic interaction between converging signalling pathways for different ranges of parameter values.
These results indicate that the six YWHAB polymorphisms are not associated with the genetic susceptibility to sporadic Creutzfeldt-Jakob disease.
14-3-3beta binding to phosphorylated CFTR (show CFTR Antibodies) augments its biogenesis by reducing retrograde retrieval of CFTR (show CFTR Antibodies) to the endoplasmic reticulum. This mechanism permits cAMP/PKA stimulation to make more CFTR (show CFTR Antibodies) available for anion secretion.
Data identified 14-3-3beta as a prognostic biomarker.
Data indicate 14-3-3 beta protein as an interacting partner of type 1 cannabinoid receptor (CB1R (show CNR1 Antibodies)).
SelW (show SEPW1 Antibodies) enhances myoblast differentiation by inhibiting TAZ (show TAZ Antibodies) binding to 14-3-3 (show YWHAQ Antibodies).
Studies suggest that insulin (show INS Antibodies) may modulate the cellular function of lipin-1 (show LPIN1 Antibodies) by regulating its subcellular localization through interactions with 14-3-3 (show YWHAQ Antibodies) proteins.
14-3-3 (show YWHAQ Antibodies) participates in the intracellular trafficking of IRS-1 (show IRS1 Antibodies)
The transcription start site was identified and the polyadenylation signals (AATAAA) were found in exon 2 of the mouse gene. In the 5'-upstream sequence, we found three cis (show CISH Antibodies) elements including a CRE sequence, a TATA box-like sequence, and a C/EBP (show CEBPA Antibodies) element.
PRAS40 (show AKT1S1 Antibodies) is a novel substrate of Akt (show AKT1 Antibodies), the phosphorylation of which leads to the binding of this protein to 14-3-3 (show YWHAQ Antibodies).
14-3-3beta is a p90 (show GPAM Antibodies) ribosomal S6 kinase (show RPS6KB1 Antibodies) (RSK (show RPS6KA1 Antibodies)) isoform 1-binding protein that negatively regulates RSK (show RPS6KA1 Antibodies) kinase activity
14-3-3beta gene plays a pivotal role in abnormal growth of tumor cells in vitro and in vivo.
These results indicate for the first time that 14-3-3 protein (show YWHAE Antibodies) plays a critical anti-apoptotic role in diabetic myocardium by inhibiting the JNK (show MAPK8 Antibodies) pathway.
aldosterone increases the expression of 14-3-3beta, which interacts with phospho-Nedd4-2 (show NEDD4L Antibodies) to block its interaction with ENaC (show SCNN1A Antibodies), thus enhancing sodium absorption by increasing apical membrane ENaC (show SCNN1A Antibodies) density
Data show that two members of Par (show AFG3L2 Antibodies) proteins, 14-3-3 (Par-5 (show YWHAZ Antibodies)) and atypical PKC (show PKC Antibodies) (aPKC), regulate the serine/threonine kinase Par-1 (show F2R Antibodies) to control Xenopus gastrulation
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.
, 14-3-3 protein beta/alpha
, brain protein 14-3-3, beta isoform
, protein 1054
, protein kinase C inhibitor protein 1
, protein kinase C inhibitor protein-1
, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide
, 14-3-3 protein beta
, tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide
, 14-3-3 protein beta-subtype
, 3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide
, prepronerve growth factor RNH-1
, tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide
, tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma
, tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide
, tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide
, tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide
, tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide
, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
, 14-3-3 beta
, 14-3-3 protein beta/alpha-A
, 14-3-3-like protein