Browse our Glutaminase (GLS) ELISA Kits

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Glutaminase ELISA Kits (GLS)
On www.antibodies-online.com are 22 Glutaminase (GLS) ELISA Kits from 9 different suppliers available. Additionally we are shipping Glutaminase Antibodies (83) and Glutaminase Proteins (6) and many more products for this protein. A total of 113 Glutaminase products are currently listed.
Synonyms:
6330442B14, A330074B06Rik, AAD20, AI195532, AI314027, B230365M23Rik, BA3155, CG8772, CG8872, Dmel\\CG42708, Dmel_CG8772, GA, GAC, GAM, GLS, GLS1, Glut, KGA, Lga, PAG, RATGLUT, si:dz87i4.2, wu:fa97e05

Glutaminase (GLS) ELISA Kits by Reactivity

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More ELISA Kits for Glutaminase Interaction Partners

Mouse (Murine) Glutaminase (GLS) interaction partners

  1. Gls2 (show GLS2 ELISA Kits) expression is regulated by the dietary protein/carbohydrate ratio. This effect was not observed in Ppara (show PPARA ELISA Kits)-null mice.

  2. studies show that the formation of large GAC oligomers is not a pre-requisite for full enzymatic activity. They also offer a mechanism by which the binding of activators like inorganic phosphate enables the activation loop to communicate with the active site to ensure maximal rates of catalysis, and promotes the opening of the lid to achieve optimal product release.

  3. Conformational changes in the activation loop of mitochondrial glutaminase C: A direct fluorescence readout that distinguishes the binding of allosteric inhibitors from activators.

  4. findings suggest that glutaminase Heterozygote mice have a pro-cognitive profile in the trace fear conditioning paradigm, and this phenotype involves activation of both hippocampus and Anterior Cingulate Cortex.

  5. studies demonstrate that GLS is required for tumorigenesis and support small molecule and genetic inhibition of GLS as potential approaches for targeting the tumor cell-autonomous dependence on GLS for cancer therapy.

  6. The Phosphate-Activated Glutaminase (show GLS2 ELISA Kits)(PAG (show PRDX1 ELISA Kits)) is mainly active in mouse kidney, brain and liver, and shows different kinetics depending on which type of PAG (show PRDX1 ELISA Kits) is expressed.

  7. The network identified in glutaminase deficient fetal mouse brain involves (a) cellular assembly and organization and (b) cell signaling and cell cycle, suggesting that Gls is crucial for neuronal maturation.

  8. kidney-type glutaminase (KGA) as a novel partner of Bmcc1s

  9. The up-regulation of neuronal glutaminase was demonstrated in situ in a murine model of HIV-1 encephalitis.

  10. identified a novel distant regulatory element located approximately 120kb downstream of the gls promoter, and examined its regulatory relevance to gls gene expression in C2C12 cells

Fruit Fly (Drosophila melanogaster) Glutaminase (GLS) interaction partners

  1. The memory deficits observed in nemy are because of reduced function of CytB561 (show CYB561 ELISA Kits) in specific brain regions that are involved in learning and memory.

Human Glutaminase (GLS) interaction partners

  1. the crystal structure of full-length KGA and present a small-angle X-ray scattering model for full-length GLS2 (show GLS2 ELISA Kits). These structures explain these proteins' compromised ability to assemble into catalytically active supra-tetrameric filaments, as previously shown for GAC.

  2. GLS1 inhibition using BPTES reduced metabolic intermediates including thymidine and carbamoyl phosphate. Reduction of thymidine and carbamoyl-phosphate synthesis by BPTES treatment exacerbated pyrimidine supply by combination with 5-FU, which induced cell death synergistically in NSCLC

  3. studies show that the formation of large GAC oligomers is not a pre-requisite for full enzymatic activity. They also offer a mechanism by which the binding of activators like inorganic phosphate enables the activation loop to communicate with the active site to ensure maximal rates of catalysis, and promotes the opening of the lid to achieve optimal product release.

  4. Glutaminase expression in tumor cells was significantly associated with a low level of tumor-infiltrating lymphocytesand poor disease-free survival in triple-negative breast cancers presenting with lymph node metastasis and high levels of tumor-infiltrating lymphocytes.

  5. Study reports that GLS1 is a direct target of miR-23a in retinal pigment epithelium cells (RPE) providing evidence for a role in maintaining RPE cell function.

  6. The relative expression of microRNA-153 and glutaminase in glioblastoma versus matched non-tumor tissues showed a reverse correlation, further indicating that microRNA-153 may negatively regulate glutaminase in vivo.

  7. High GLS1 expression is associated with epithelial-mesenchymal transition in cancer.

  8. Data suggest that glutaminase C (GAC) inhibition maybe a potential treatment strategy for acquired erlotinib-resistant non-small cell lung cancer (NSCLC).

  9. Findings indicate a role for transcription factor c-Jun (show JUN ELISA Kits) as a driver of cancer cell metabolic reprogramming, and suggest that cancers overexpressing JUN (show JUN ELISA Kits) may be especially sensitive to glutaminase (GLS)-targeted therapies.

  10. GLS1 was identified as a potential downstream target of the miR (show MLXIP ELISA Kits)-192/-204-HOTTIP axis in hepatocellular carcinoma.

Glutaminase (GLS) Antigen Profile

Antigen Summary

This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with Glutaminase (GLS)

  • glutaminase (GLS) Elisa Kit
  • glutaminase (Gls) Elisa Kit
  • glutaminase (gls) Elisa Kit
  • glutaminase b (glsb) Elisa Kit
  • CG42708 gene product from transcript CG42708-RA (CG42708) Elisa Kit
  • hypothetical protein (glutaminase) Elisa Kit
  • glutaminase (glsA-2) Elisa Kit
  • glutaminase (Arnit_3113) Elisa Kit
  • glutaminase (Celal_2913) Elisa Kit
  • Glutaminase (Odosp_0379) Elisa Kit
  • Glutaminase (Odosp_1505) Elisa Kit
  • Glutaminase (Celly_0289) Elisa Kit
  • glutaminase (Weevi_2101) Elisa Kit
  • glutaminase (Mesop_4683) Elisa Kit
  • glutaminase 2 (liver, mitochondrial) (Gls2) Elisa Kit
  • 6330442B14 Elisa Kit
  • A330074B06Rik Elisa Kit
  • AAD20 Elisa Kit
  • AI195532 Elisa Kit
  • AI314027 Elisa Kit
  • B230365M23Rik Elisa Kit
  • BA3155 Elisa Kit
  • CG8772 Elisa Kit
  • CG8872 Elisa Kit
  • Dmel\\CG42708 Elisa Kit
  • Dmel_CG8772 Elisa Kit
  • GA Elisa Kit
  • GAC Elisa Kit
  • GAM Elisa Kit
  • GLS Elisa Kit
  • GLS1 Elisa Kit
  • Glut Elisa Kit
  • KGA Elisa Kit
  • Lga Elisa Kit
  • PAG Elisa Kit
  • RATGLUT Elisa Kit
  • si:dz87i4.2 Elisa Kit
  • wu:fa97e05 Elisa Kit

Protein level used designations for Glutaminase (GLS) ELISA Kits

glutaminase kidney isoform, mitochondrial , phosphate-activated glutaminase , glutaminase C , glutaminase , CG42708-PA , CG42708-PB , CG42708-PC , CG42708-PD , CG42708-PE , CG42708-PF , CG42708-PH , CG42708-PI , hypothetical protein , Glutaminase , K-glutaminase , L-glutamine amidohydrolase , glutaminase, phosphate-activated , L-glutaminase , glutaminase liver isoform, mitochondrial , liver mitochondrial glutaminase

GENE ID SPECIES
525335 Bos taurus
488448 Canis lupus familiaris
399525 Sus scrofa
14660 Mus musculus
100069617 Equus caballus
470606 Pan troglodytes
5620641 Bacillus pumilus SAFR-032
564746 Danio rerio
424043 Gallus gallus
36396 Drosophila melanogaster
172547 Caenorhabditis elegans
174282 Caenorhabditis elegans
1086611 Bacillus anthracis str. Ames
2815154 Bacillus anthracis str. 'Ames Ancestor'
9173316 Arcobacter nitrofigilis DSM 7299
10145336 Cellulophaga algicola DSM 14237
10252085 Odoribacter splanchnicus DSM 220712
10253226 Odoribacter splanchnicus DSM 220712
10262273 Cellulophaga lytica DSM 7489
10283366 Weeksella virosa DSM 16922
10828538 Mesorhizobium opportunistum WSM2075
2744 Homo sapiens
24398 Rattus norvegicus
216456 Mus musculus
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