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Tryptophan Hydroxylase 1 ELISA Kits (TPH1)
On www.antibodies-online.com are 37 Tryptophan Hydroxylase 1 (TPH1) ELISA Kits from 12 different suppliers available. Additionally we are shipping Tryptophan Hydroxylase 1 Antibodies (150) and Tryptophan Hydroxylase 1 Proteins (8) and many more products for this protein. A total of 200 Tryptophan Hydroxylase 1 products are currently listed.
Synonyms:
LOC100229598, SERGEF, Tph, tph1, tphD1, TPRH, TRPH

Tryptophan Hydroxylase 1 (TPH1) ELISA Kits by Reactivity

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Caenorhabditis elegans (C. elegans) Tryptophan Hydroxylase 1 (TPH1) interaction partners

  1. A gene-expression-based neural code for food abundance that modulates lifespan includes daf-7 that primarily regulates gene-expression variability, while tph-1 primarily regulates the dynamic range of gene-expression responses.

  2. tph-1 mutants failed to exhibit ethanol interference with gustatory plasticity in Caenorhabditis elegans

Human Tryptophan Hydroxylase 1 (TPH1) interaction partners

  1. This study demonstrates that both TPH1 and TPH2 (show TDO2 ELISA Kits) are expressed in human and mouse placenta throughout pregnancy and helps to better understand the placental serotonin system, which is crucial for healthy pregnancy and fetal development.

  2. Genetic association studies have revealed contradictory results about the effect of the TPH1 A218C (rs1800532) polymorphism on suicidal behavior in different populations. Investigated A218C polymorphism in 109 suicide attempters and 98 healthy controls. Our results provide evidence that A allele of TPH1 A218C polymorphism may be associated with suicidal behavior in Turkish population

  3. The regulatory domain of isoform 1 of tryptophan hydroxylase was expressed and purified; mutagenesis of Cys64 was required to prevent formation of disulfide-linked dimers.

  4. Associations between serotonin transporter (show SLC6A4 ELISA Kits) gene and tryptophan hydroxylase 1 polymorphisms and several Temperament and Character Inventory dimensions and subdimensions were revealed in subjects with bipolar disorder.

  5. there was a significant interaction between the TPH1 A218C A/C and 5-HTTLPR (show SLC6A4 ELISA Kits) S+ gene polymorphisms in opiate-dependent, but not in alcohol-dependent patients.

  6. Polymorphisms in the TPH1 gene may be represented by diminished activity in lateral areas of the PFC (show CFP ELISA Kits) underlying response inhibition.

  7. Decoy receptor 3 (show TNFRSF6B ELISA Kits) regulates the expression of tryptophan hydroxylase 1 in rheumatoid synovial fibroblasts

  8. TPH1 is functionally expressed in human coronary artery smooth muscle cells.

  9. This review showed no evidence for the association of antidepressant response with an A218C SNP in the TPH1 gene.

  10. The study provides evidence that A218C/A779C TPH-1 variants may be a risk factor to manifest suicidal behavior at the clinical level, which is in agreement with previously reported meta-analyses.[review and meta-analysis]

Mouse (Murine) Tryptophan Hydroxylase 1 (TPH1) interaction partners

  1. Prolactin (show PRL ELISA Kits)-induced Tph1 expression.

  2. Tph1-deficient mice fed a high-fat diet (HFD) are protected from obesity, insulin (show INS ELISA Kits) resistance and nonalcoholic fatty liver disease (NAFLD (show TSC2 ELISA Kits)) while exhibiting greater energy expenditure by brown adipose tissue.

  3. Lack of tryptophan hydroxylase-1 in mice results in gait abnormalities.

  4. ZBP-89 (show ZNF148 ELISA Kits) directly binds to the Tph1 promoter, which is required for its basal and butyrate-inducible expression.

  5. TPH1 deficiency or inhibition reduces allergic airway inflammation. Platelet-derived 5-HT (show DDC ELISA Kits) is pivotal in AAI and lack of 5-HT (show DDC ELISA Kits) leads to impaired Th2 priming capacity of bone marrow dendritic cells.

  6. Data indicate that tryptophan hydroxylase (Tph)1-deficient mice, lacking non-neuronal serotonin, showed mild leukocytosis.

  7. Data show that Tph-1 (tryptophan hydroxylase-1) is a potent regulator of immunity.

  8. Parallel to Tph1 mRNA and protein induction, islet serotonin content increased to a peak level that was 200-fold higher than basal. Interestingly, only a subpopulation of the beta cells was serotonin-positive in vitro and in vivo.

  9. nonneuronal tph1 gene has a role in cardiac function with peripheral serotonin

  10. Review. TPH1 is expressed in the pineal gland and the enterochromaffin cells. Loss of TPH1 gene expression, and thus of peripheral 5-HT (show DDC ELISA Kits), leads to a cardiac dysfunction phenotype.

Tryptophan Hydroxylase 1 (TPH1) Antigen Profile

Antigen Summary

This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.

Alternative names and synonyms associated with Tryptophan Hydroxylase 1 (TPH1)

  • tryptophan hydroxylase 1 (tph1) Elisa Kit
  • tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a (tph1a) Elisa Kit
  • TryPtophan Hydroxylase (tph-1) Elisa Kit
  • tryptophan hydroxylase 1 (TPH1) Elisa Kit
  • tryptophan hydroxylase 1 (LOAG_02149) Elisa Kit
  • tryptophan hydroxylase 1 (LOC100229598) Elisa Kit
  • tryptophan hydroxylase (Tph) Elisa Kit
  • tryptophan 5-hydroxylase 1 (Tsp_05203) Elisa Kit
  • tryptophan hydroxylase 1 (Tph1) Elisa Kit
  • LOC100229598 Elisa Kit
  • SERGEF Elisa Kit
  • Tph Elisa Kit
  • tph1 Elisa Kit
  • tphD1 Elisa Kit
  • TPRH Elisa Kit
  • TRPH Elisa Kit

Protein level used designations for TPH1

tryptophan 5-hydroxylase , tryptophan 5-monooxygenase , tph1-1 , tryptophan hydroxylase (tryptophan 5-monooxygenase , TryPtophan Hydroxylase family member (tph-1) , tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) , tryptophan hydroxylase 1 , tryptophan 5-hydroxylase 1-like , tryptophan hydroxylase , tryptophan 5-hydroxylase 1 , L-tryptophan hydroxylase , indoleacetic acid-5-hydroxylase , tryptophan 5-monooxygenase 1 , tryptophan hydroxylase (tryptophan 5-monooxygenase) , secretion regulating guanine nucleotide exchange factor

GENE ID SPECIES
387560 Xenopus laevis
352943 Danio rerio
174227 Caenorhabditis elegans
695363 Macaca mulatta
9939535 Loa loa
100056614 Equus caballus
100229598 Taeniopygia guttata
100415029 Callithrix jacchus
100467699 Ailuropoda melanoleuca
100511002 Sus scrofa
100534573 Oreochromis niloticus
100601780 Nomascus leucogenys
10908943 Trichinella spiralis
7166 Homo sapiens
100101558 Oryctolagus cuniculus
24848 Rattus norvegicus
21990 Mus musculus
611956 Canis lupus familiaris
781941 Bos taurus
395799 Gallus gallus
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