Browse our UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 Proteins (B4GALT5)

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UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 Proteins (B4GALT5)
On www.antibodies-online.com are 6 UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 (B4GALT5) Proteins from 2 different suppliers available. Additionally we are shipping UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 Antibodies (38) and UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 Kits (6) and many more products for this protein. A total of 55 UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 products are currently listed.
Synonyms:
9430078I07Rik, AW049941, AW539721, B4Gal-T5, BETA4-GALT-IV, beta4Gal-T5, beta4GalT-V, gt-V
list all proteins Gene Name GeneID UniProt
B4GALT5 9334 O43286
B4GALT5 56336 Q9JMK0

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UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 Proteins (B4GALT5) by Origin

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More Proteins for UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 Interaction Partners

Human UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 (B4GALT5) interaction partners

  1. B4GALT1 (show B4GALT1 Proteins) and B4GALT5, two members of B4GALT (show B4GALNT2 Proteins) gene family, are involved in the development of multidrug resistance of human leukemia cells.

  2. The expression of the beta-1,4-GalT V gene has been shown to be regulated by transcription factors Sp1 (show PSG1 Proteins) and Ets-1 (show ETS1 Proteins) in cancer cells.(review)

  3. Over-expression of beta-1,4-galactosyltransferase V increases the growth of astrocytoma cell line

  4. results suggest that GalT (show GALT Proteins) V functioned as a novel glioma growth activator and might represent a novel target in glioma therapy

  5. Ets-1 (show ETS1 Proteins) enhances expression of the beta-1,4-GalT V gene through activation of the Sp1 (show PSG1 Proteins) gene in cancer cells

  6. sulfated (show SULF1 Proteins) keratan sulfate is produced by beta3GNT7 (show B3GNT7 Proteins), beta4GalT4, CGn6ST, and KSG6ST

Mouse (Murine) UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 (B4GALT5) interaction partners

  1. These results strongly indicate that the amounts of Lac (show LCT Proteins)-Cer (show CBLN1 Proteins) synthesized by beta4GalT5 correlate with the tumorigenic potentials of malignantly transformed cells.

  2. Data indicate that mice fed D- threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol (D-PDMP), an inhibitor of glucosylceramide synthase (show UGCG Proteins) and lactosylceramide synthase showed marked reduction in tumor volume.

  3. The expression of the beta-1,4-GalT V gene has been shown to be regulated by transcription factors Sp1 (show SP1 Proteins) and Ets-1 (show ETS1 Proteins) in cancer cells.(review)

  4. beta-1,4-galactosyltransferase V is involved in lactosylceramide biosynthesis

  5. Loss of beta4Gal-T5 is associated with hematoma and defect in extra-embryonic development.

  6. The results indicate that the growth is delayed by one to one and half day in B4galt5-/- embryos when compared to B4galt5+/- embryos, which results in early death of the embryos by E10.5, probably due to hematopoietic and/or placental defects.

UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 (B4GALT5) Protein Profile

Protein Summary

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose\; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The function of the enzyme encoded by this gene is not clear. This gene was previously designated as B4GALT4 but was renamed to B4GALT5. In the literature it is also referred to as beta4GalT2.

Alternative names and synonyms associated with UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 5 (B4GALT5)

  • UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (B4GALT5)
  • UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 (B4galt5)
  • 9430078I07Rik protein
  • AW049941 protein
  • AW539721 protein
  • B4Gal-T5 protein
  • BETA4-GALT-IV protein
  • beta4Gal-T5 protein
  • beta4GalT-V protein
  • gt-V protein

Protein level used designations for B4GALT5

UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5 , UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 , UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5 , beta-1,4-GalT II , beta-1,4-GalT IV , beta-1,4-GalTase 5 , beta-1,4-galactosyltransferase 5 , beta-1.4-galactosyltransferase V , beta4-GalT IV , b4Gal-T5 , beta-1,4-galactosyltransferase V , beta4Gal-T5

GENE ID SPECIES
9334 Homo sapiens
56336 Mus musculus
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