You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our IDUA Proteins (IDUA)

Full name:
Iduronidase, alpha-L- Proteins (IDUA)
On www.antibodies-online.com are 12 Iduronidase, alpha-L- (IDUA) Proteins from 4 different suppliers available. Additionally we are shipping IDUA Antibodies (61) and IDUA Kits (20) and many more products for this protein. A total of 96 IDUA products are currently listed.
Synonyms:
6030426D08, alpha-L-iduronidase, fgfrl1, IDA, IDUA, MGC80842, MPS1, si:ch211-12e13.9, zgc:64084
list all proteins Gene Name GeneID UniProt
Rat IDUA IDUA 360904  
IDUA 3425 P35475
IDUA 15932  

Show all synonyms

IDUA Proteins (IDUA) by Origin

Select your origin of interest

More Proteins for IDUA Interaction Partners

Zebrafish Iduronidase, alpha-L- (IDUA) interaction partners

  1. In the absence of Fgfrl1a, larvae fail to express the transcription factor glial cells missing 2 (gcm2 (show GCM2 Proteins)), a gene necessary for cartilage and gill filament formation, in the ectodermal lining of the branchial arches.

Human Iduronidase, alpha-L- (IDUA) interaction partners

  1. Molecular studies results unveiled the predominance of(Pro533Arg) IDUA variation in a series of 13 Algerian patients with Mucopolysaccharidosis Type I presented mainly with an attenuated phenotype.

  2. A new IDUA variant that alters the structure of the signal peptide associated with mucopolysaccharidosis type I is reported.

  3. Amino acid substitutions in alpha-L-iduronidase determine the severity of mucopolysaccharidosis type I.

  4. The alpha-L-iduronidase missense mutation causing L238Q substitution, when paired with a nonsense mutation, is associated with significant, late-onset brain disease.

  5. We conclude that this procedure for determining residual IDUA activity in fibroblasts of MPS I patients may be helpful to predict MPS I phenotype.

  6. The IDUA structures and biochemical analysis of the disease-relevant P533R mutation have enabled us to correlate the effects of mutations in IDUA to clinical phenotypes.

  7. Data show that alpha-l-iduronidase (hIDUA) enzyme activity was highly correlated with the N-glycan attached to N372.

  8. X-ray diffraction analysis of human alpha-L-iduronidase

  9. Transfer of a high level of human alpha-L-iduronidase gene into the central nervous system (CNS) of MPS I mutant mice susceptible to mucopolysaccharidosis (MPS) improves the outcome for MPS when a high level of CNS gene expression is achieved.

  10. A previously unreported IDUA splice site mutation (NG_008103.1:g.21632G>C; NM_000203.3:c.1727+3G>C) causing a Hurler phenotype in a patient heterozygous for the common p.Q70X (NG_008103.1:g.5862C>T) mutation.

Mouse (Murine) Iduronidase, alpha-L- (IDUA) interaction partners

  1. This study demonstrated that the distribuation of bis (show BAG3 Proteins)(monoacylglycero)phosphate in brain of mucopolysaccharidosis 1 (Hurler) mouse.

  2. Mucopolysaccharidosis type I, unique structure of accumulated heparan sulfate and increased N-sulfotransferase activity in mice lacking alpha-l-iduronidase.

  3. Studies show that mouse Idua-W392X mutation is analogous to the human IDUA-W402X mutation commonly found in MPS I-H patients.

  4. Data show that late-stage erythroid cells, transduced with a tissue-specific lentiviral vector, can deliver alpha-L-iduronidase continuously and can correct the disease phenotype in both viscera and CNS of MPS I mice.

  5. The results indicate that Idua(-/-) mice present deficits in long-term memory for aversive training and reduced exploratory behavior.

  6. IDUA(-/-) mice from adolescence to maturity, exhibited locomotor and anxiety-like compulsive behaviors, spatial learning and memory, visual recognition and short-term non-associative memory retention.

IDUA Protein Profile

Protein Summary

This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).

Alternative names and synonyms associated with IDUA

  • iduronidase, alpha-L- (idua)
  • iduronidase, alpha-L- (IDUA)
  • fibroblast growth factor receptor-like 1a (fgfrl1a)
  • fibroblast growth factor receptor-like 1 (FGFRL1)
  • alpha-l-iduronidase (AaeL_AAEL004402)
  • alpha-L-iduronidase (LOC100231378)
  • alpha-L-iduronidase (Idua)
  • iduronidase, alpha-L- (Idua)
  • 6030426D08 protein
  • alpha-L-iduronidase protein
  • fgfrl1 protein
  • IDA protein
  • IDUA protein
  • MGC80842 protein
  • MPS1 protein
  • si:ch211-12e13.9 protein
  • zgc:64084 protein

Protein level used designations for Iduronidase, alpha-L- Proteins (IDUA)

iduronidase, alpha-L- , alpha-L-iduronidase , fibroblast growth factor receptor-like 1 , alpha-l-iduronidase

GENE ID SPECIES
446866 Xenopus laevis
511050 Bos taurus
567720 Danio rerio
100146682 Equus caballus
100560915 Anolis carolinensis
393347 Danio rerio
532327 Bos taurus
5564727 Aedes aegypti
100231378 Taeniopygia guttata
360904 Rattus norvegicus
100505382 Canis lupus familiaris
3425 Homo sapiens
15932 Mus musculus
427294 Gallus gallus
Selected quality suppliers for IDUA Proteins (IDUA)
Did you look for something else?