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Browse our Inositol Monophosphatase Domain Containing 1 (IMPAD1) ELISA Kits

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Inositol Monophosphatase Domain Containing 1 ELISA Kits (IMPAD1)
On www.antibodies-online.com are 5 Inositol Monophosphatase Domain Containing 1 (IMPAD1) ELISA Kits from 1 different suppliers available. Additionally we are shipping Inositol Monophosphatase Domain Containing 1 Antibodies (34) and Inositol Monophosphatase Domain Containing 1 Proteins (8) and many more products for this protein. A total of 53 Inositol Monophosphatase Domain Containing 1 products are currently listed.
Synonyms:
1110001C20Rik, AA408880, AI451589, AL022796, B230207P20, gPAPP, IMP-3, IMP 3, IMP3, impa3, Jaws, PSL2, RGD1306455
list all ELISA KIts Gene Name GeneID UniProt
IMPAD1 54928 Q9NX62
IMPAD1 312952 D4AD37
IMPAD1 242291 Q80V26

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Inositol Monophosphatase Domain Containing 1 (IMPAD1) ELISA Kits by Reactivity

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More ELISA Kits for Inositol Monophosphatase Domain Containing 1 Interaction Partners

Human Inositol Monophosphatase Domain Containing 1 (IMPAD1) interaction partners

  1. In human B cells, SPPL2a is indispensable for turnover of CD74 N-terminal fragment. A human 15q21.2 microdeletion leads to loss of SPPL2a transcript and protein.

  2. Regulated intramembrane proteolysis of the frontotemporal lobar degeneration risk factor, TMEM106B, by signal peptide peptidase-like 2a (SPPL2a).

  3. concluded that IMPAD1 should be screened for patients with Catel-Manzke and additional features

  4. Data show that endogenous SPPL2a - in agreement with overexpression studies - is localised in membranes of lysosomes/late endosomes.

  5. Affected individuals carried homozygous missense mutations in IMPAD1, the gene coding for gPAPP, a Golgi-resident nucleotide phosphatase that hydrolyzes phosphoadenosine phosphate (PAP (show REG3A ELISA Kits)), the byproduct of sulfotransferase reactions, to AMP (show APRT ELISA Kits).

  6. SPP, SPPL2a, -2b, -2c, and -3 probably cleave type II-oriented substrate peptides as shown by consensus analysis

  7. ADAM10 (show ADAM10 ELISA Kits) and SPPL2a were identified as two proteases implicated in FasL (show FASL ELISA Kits) processing and release of the FasL (show FASL ELISA Kits) intracellular domain, which has been shown to be important for retrograde FasL (show FASL ELISA Kits) signaling

  8. SPPL2a and SPPL2b (show SPPL2B ELISA Kits) mediate the intramembrane cleavage, whereas neither SPP nor SPPL3 is capable of processing the Bri2 (show ITM2B ELISA Kits) N-terminal fragment.

Mouse (Murine) Inositol Monophosphatase Domain Containing 1 (IMPAD1) interaction partners

  1. Golgi plays an important role in glycosaminoglycan sulfation and define a function for gPAPP in the formation of skeletal elements derived through endochondral ossification[3'-phosphoadenosine 5'-phosphate phosphatase]

  2. identify JAWS as a key regulator of chondrogenesis and synovial joint positioning required for the restriction of joint formation to discrete stereotyped locations in the embryonic skeleton

Inositol Monophosphatase Domain Containing 1 (IMPAD1) Antigen Profile

Antigen Summary

This gene encodes a member of the GXGD family of aspartic proteases, which are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions, as well as a member of the signal peptide peptidase-like protease (SPPL) family. This protein is expressed in all major adult human tissues and localizes to late endosomal compartments and lysosomal membranes. A pseudogene of this gene also lies on chromosome 15.

Alternative names and synonyms associated with Inositol Monophosphatase Domain Containing 1 (IMPAD1)

  • inositol monophosphatase domain containing 1 (IMPAD1) Elisa Kit
  • inositol monophosphatase domain containing 1 (Impad1) Elisa Kit
  • inositol monophosphatase domain containing 1 (impad1) Elisa Kit
  • signal peptide peptidase like 2A (SPPL2A) Elisa Kit
  • 1110001C20Rik Elisa Kit
  • AA408880 Elisa Kit
  • AI451589 Elisa Kit
  • AL022796 Elisa Kit
  • B230207P20 Elisa Kit
  • gPAPP Elisa Kit
  • IMP-3 Elisa Kit
  • IMP 3 Elisa Kit
  • IMP3 Elisa Kit
  • impa3 Elisa Kit
  • Jaws Elisa Kit
  • PSL2 Elisa Kit
  • RGD1306455 Elisa Kit

Protein level used designations for IMPAD1

inositol monophosphatase domain containing 1 , myo-inositol monophosphatase A3 , inositol monophosphatase 3 , inositol monophosphatase 3-like , Golgi 3-prime phosphoadenosine 5-prime phosphate 3-prime phosphatase , IMPase 3 , golgi-resident PAP phosphatase , inositol monophosphatase domain-containing protein 1 , inositol-1(or 4)-monophosphatase 3 , Ac2-190 , Golgi-resident PAP phosphatase , IMP 3 , Inositol monophosphatase domain-containing protein 1 , Inositol-1(or 4)-monophosphatase 3 , Myo-inositol monophosphatase A3 , IMP-3 , SPP-like 2A , intramembrane cleaving protease , intramembrane protease 3 , presenilin-like protein 2 , signal peptide peptidase-like 2A

GENE ID SPECIES
421132 Gallus gallus
464188 Pan troglodytes
696893 Macaca mulatta
100343037 Oryctolagus cuniculus
100453710 Pongo abelii
100602566 Nomascus leucogenys
54928 Homo sapiens
312952 Rattus norvegicus
477890 Canis lupus familiaris
100156925 Sus scrofa
532797 Bos taurus
242291 Mus musculus
100395037 Callithrix jacchus
414458 Xenopus laevis
84888 Homo sapiens
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