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Browse our LYVE1 Proteins (LYVE1)

Full name:
Lymphatic Vessel Endothelial Hyaluronan Receptor 1 Proteins (LYVE1)
On www.antibodies-online.com are 34 Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) Proteins from 11 different suppliers available. Additionally we are shipping LYVE1 Antibodies (260) and LYVE1 Kits (17) and many more products for this protein. A total of 320 LYVE1 products are currently listed.
Synonyms:
1200012G08Rik, Crsbp-1, HAR, Lyve-1, LYVE1, Xlkd1
list all proteins Gene Name GeneID UniProt
LYVE1 10894 Q9Y5Y7
LYVE1 114332 Q8BHC0
Rat LYVE1 LYVE1 293186  

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LYVE1 Proteins (LYVE1) by Origin

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Top referenced LYVE1 Proteins

  1. Human LYVE1 Protein expressed in Hi-5 - ABIN668039 : Banerji, Ni, Wang, Clasper, Su, Tammi, Jones, Jackson: LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. in The Journal of cell biology 1999 (PubMed)
    Show all 2 references for ABIN668039

More Proteins for LYVE1 Interaction Partners

Human Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) interaction partners

  1. These findings reveal binding is dependent not just on clustering but also on the biochemical properties of LYVE-1 homodimers. They also mark LYVE-1 as the first Link protein (show HAPLN1 Proteins) superfamily member requiring covalent homodimerization for function and suggest the interchain disulfide acts as a redox switch in vivo.

  2. LYVE1 expression is significantly upregulated in human masticatory mucosa during wound healing

  3. Immunostaining analyses in psoria (show VEGFA Proteins)sis skin lesions suggested that the ectodomain shedding of LYVE-1 occurred in lymphatic vessels undergoing chronic inflammation. These results indicate that the ectodomain shedding of LYVE-1 might be involved in promoting pathological lymphangiogenesis.

  4. These results demonstrate the prerequisite of a critical LYVE-1 threshold density and show that hyaluronan binding may be elicited in lymphatic endothelium by surface clustering with divalent LYVE-1 mAbs.

  5. We have established a novel, three-protein biomarker panel that is able to detect patients with early-stage pancreatic cancer in urine specimens:LYVE-1, REG1A (show REG1A Proteins), and TFF1 (show TFF1 Proteins) were selected as candidate biomarkers

  6. Data (including data from studies in knockout mice) suggest LYVE1 mediates adhesion of group A Streptococci (GAS) to lymphatic vesicular endothelium via capsular hyaluronan; this appears to be critical factor for lymphatic trafficking of GAS in vivo.

  7. High expression of LYVE-1 is associated with atherosclerotic arteries.

  8. Data indicate that detection of lymphatic vascular invasion (LVI) can be optimized by specific D2-40 or LYVE-1 staining.

  9. High-low cell surface HA content of tumor cells through the interaction with LYVE-1 leads to adhesion differences.

  10. FGF2 (show FGF2 Proteins) binds to LYVE-1 with a higher affinity than any other known LYVE-1-binding molecules, such as hyaluronan or PDGF (show PDGFA Proteins)-BB. Glycosylation of LYVE-1 is important for FGF2 (show FGF2 Proteins) binding.

Mouse (Murine) Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) interaction partners

  1. the LYVE-1-expressing cells might be involved in the uptake of hyaluronan and other waste products as well as foreign particles circulating in the blood and lymph while participating in the subsequent degradation in relay with adjacent macrophage populations.

  2. Immunostaining analyses in VEGF-A (show VEGFA Proteins) transgenic skin suggested that the ectodomain shedding of LYVE-1 occurred in lymphatic vessels undergoing chronic inflammation. These results indicate that the ectodomain shedding of LYVE-1 might be involved in promoting pathological lymphangiogenesis.

  3. Endogenous hyaluronan on the surface of macrophages can engage LYVE-1, facilitating their adhesion and transit across lymphatic endothelium.

  4. MT1-MMP (show MMP14 Proteins) directly cleaves LYVE-1 on lymphatic endothelial cells to inhibit LYVE-1-mediated lymphangiogenic responses and restrains the production of VEGF-C (show VEGFC Proteins).

  5. Data (including data from studies in knockout mice) suggest Lyve1 mediates adhesion of group A Streptococci (GAS) to lymphatic vesicular endothelium via capsular hyaluronan; this appears to be critical factor for lymphatic trafficking of GAS in vivo.

  6. Data show that the expression of lymphatic vessel endothelial hyaluronan receptor 1 (LYVE 1) was similar with vascular endothelial growth factor C (VEGF-C (show VEGFC Proteins)), but its peak appeared 1-2 d later than that of VEGF-C (show VEGFC Proteins).

  7. LMW-HA may play a critical role in the processes required for lymphangiogenesis through interactions with its receptor LYVE-1 and triggering intracellular signal cascades.

  8. Studied the specific targeting property of lymphatic vessel endothelial hyaluronan receptor-1 binding polyethylene glycol-coated ultrasmall superparamagnetic iron oxide (LYVE-1-PEG (show PAEP Proteins)-USPIO) nanoparticles to mouse lymphatic endothelial cells.

  9. Reelin (show RELN Proteins)-deficient mice showed abnormal collecting lymphatic vessels, characterized by a reduced number of SMCs, abnormal expression of lymphatic capillary marker lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1), and impaired function

  10. report intact CD31 (show PECAM1 Proteins)(+) corneal lymphatic capillary endothelial cells that do not express LYVE-1. The number of LYVE-1(-) gaps initially increased until 8 wk of age but was significantly reduced in aged mice.

Cow (Bovine) Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) interaction partners

  1. CRSBP-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence.

LYVE1 Protein Profile

Protein Summary

This gene encodes a type I integral membrane glycoprotein. The encoded protein acts as a receptor and binds to both soluble and immobilized hyaluronan. This protein may function in lymphatic hyaluronan transport and have a role in tumor metastasis.

Alternative names and synonyms associated with LYVE1

  • lymphatic vessel endothelial hyaluronic acid receptor 1-like (LOC560618)
  • lymphatic vessel endothelial hyaluronan receptor 1 (LOC100347960)
  • lymphatic vessel endothelial hyaluronan receptor 1 (LYVE1)
  • lymphatic vessel endothelial hyaluronan receptor 1 (Lyve1)
  • 1200012G08Rik protein
  • Crsbp-1 protein
  • HAR protein
  • Lyve-1 protein
  • LYVE1 protein
  • Xlkd1 protein

Protein level used designations for LYVE1

lymphatic vessel endothelial hyaluronan receptor 1 , extracellular link domain containing 1 , lymphatic endothelial hyaluronan receptor LYVE-1 , lymphatic vessel endothelial hyaluronic acid receptor 1 , cell surface retention sequence binding protein-1 , cell surface retention sequence-binding protein 1 , extracellular link domain-containing 1 , extracellular link domain-containing protein 1 , hyaluronic acid receptor , extra cellular link domain-containing 1 , lymphatic vessel endothelial HA receptor-1 , lymphatic vessel endothelial HA recptor-1

GENE ID SPECIES
560618 Danio rerio
100347960 Oryctolagus cuniculus
397626 Sus scrofa
423038 Gallus gallus
451024 Pan troglodytes
611529 Canis lupus familiaris
702941 Macaca mulatta
10894 Homo sapiens
114332 Mus musculus
293186 Rattus norvegicus
404179 Bos taurus
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