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Browse our anti-Syndecan 2 (SDC2) Antibodies

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anti-Syndecan 2 Antibodies (SDC2)
On are 47 Syndecan 2 (SDC2) Antibodies from 14 different suppliers available. Additionally we are shipping Syndecan 2 Kits (12) and Syndecan 2 Proteins (11) and many more products for this protein. A total of 74 Syndecan 2 products are currently listed.
4833414L08Rik, AA960457, cb440, CD362, HSPG, Hspg1, Synd2, syndecan-2, zgc:103676

Most Popular Reactivities for anti-Syndecan 2 (SDC2) Antibodies

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Top referenced anti-Syndecan 2 Antibodies

  1. Human Monoclonal SDC2 Primary Antibody for FACS - ABIN4896005 : Connor, Felder, Kapur, Onujiogu: DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1. in BMC cancer 2012 (PubMed)
    Show all 4 references for ABIN4896005

  2. Human Polyclonal SDC2 Primary Antibody for WB - ABIN948451 : Lim, Couchman: Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases. in Biochimica et biophysica acta 2014 (PubMed)
    Show all 2 references for ABIN948451

  3. Human Monoclonal SDC2 Primary Antibody for FACS - ABIN4899374 : Cabezón, Sintes, Llinàs, Benitez-Ribas: Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. in Immunology letters 2010 (PubMed)
    Show all 2 references for ABIN4899374

  4. Mouse (Murine) Polyclonal SDC2 Primary Antibody for FACS, IHC - ABIN4899370 : Sun, Gomes, Chen, Frankenberger, Sankarasharma, Chung, Chada, Rosner: RKIP and HMGA2 regulate breast tumor survival and metastasis through lysyl oxidase and syndecan-2. in Oncogene 2014 (PubMed)

More Antibodies against Syndecan 2 Interaction Partners

Zebrafish Syndecan 2 (SDC2) interaction partners

  1. Results uncover a novel Sdc2-Tbx16-Fgf2 (show FGF2 Antibodies) pathway that regulates epithelial cell morphogenesis.

  2. We show here that sdc2,sdc3 (show SDC3 Antibodies) and sdc4 (show SDC4 Antibodies) are expressed in the zebrafish embryonic brain during the major period of axon growth. These genes show differing expression patterns in the brain which provides putative insights into their functional specificity.

  3. Syndecan-2 is essential for angiogenic sprouting during zebrafish development

  4. Data show that syndecan 2 expressed in the extra-embryonic yolk syncytial layer acts locally at the YSL-embryo interface to direct organ primordia migration, and is required for fibronectin (show FN1 Antibodies) and laminin matrix assembly throughout the embryo.

Human Syndecan 2 (SDC2) interaction partners

  1. SDC2 is overexpressed in Leri's pleonosteosis. The minor allele of a missense SDC2 variant, p.Ser71Thr, could confer protection against systemic sclerosis.

  2. In this review we considered the function of syndecan-2, the structure of syndecan-2 and its role in the formation of amyloid plaques.

  3. HIV matrix protein p17 (show PDE6D Antibodies) is pro-fibrogenic through its interactions both with CXCR2 (show CXCR2 Antibodies) and syndecan-2 on activated HSCs

  4. The results demonstrate the importance of PDZ (show INADL Antibodies)-binding domain of syndecan-2 for controlling LFA-1 (show ITGAL Antibodies) affinity and cell adhesion.

  5. SDC2 expression was higher in skin melnaoma cells. It enhanced tyrosinase activity by increasing the membrane and melanosome localization of protein kinase CbetaII. UVB-induced up-regulation was required for UVB-induced melanin synthesis.

  6. syndecan 2 shows no changes associated to histological grade of Prostate cancer

  7. RhoA (show RHOA Antibodies), but not RhoC (show RHOC Antibodies) was shown to be essential for the anchored phenotype of breast carcinoma cells that accompanied siRNA-mediated loss of syndecan-2.

  8. RKIP (show PEBP1 Antibodies), LOX (show LOX Antibodies) and SDC2 are coordinately regulated and collectively encompass a prognostic signature for metastasis-free survival in ER-negative breast cancer patients

  9. Taken together, these data suggest that IL-1alpha regulates extracellular domain shedding of syndecan-2 through regulation of the MAP kinase (show MAPK1 Antibodies)-mediated MMP-7 (show MMP7 Antibodies) expression in colon cancer cells.

  10. Clinical validation of SDC2 methylation in serum DNA by quantitative methylation-specific PCR demonstrated a high sensitivity of 87.0% (95% CI, 80.0% to 92.3%) in detecting cancers.

Mouse (Murine) Syndecan 2 (SDC2) interaction partners

  1. In mouse melanoma cells, siRNA-mediated knockdown of syndecan-2 was associated with reduced melanin synthesis, whereas overexpression of syndecan-2 increased melanin synthesis.

  2. The N-terminal growth-factor-like domain of amyloid-beta precursor protein is necessary for protein-receptor binding, whereas the E2-domain mediates interaction with membrane-anchored syndecan 2 and glypican 1 (show GPC1 Antibodies).

  3. The repression of syndecan-2 by Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies)/TCF (show HNF4A Antibodies) signaling contributes to the resistance of osteosarcoma cells to doxorubicin.

  4. MC1R (show MSHR Antibodies) regulates melanoma cell migration via inhibition of syndecan-2 expression.

  5. Sarm1 (show SARM1 Antibodies), a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphogenesis.

  6. RGD-independent cell adhesion via a tissue transglutaminase (show TGM2 Antibodies) 2 (show TGM2 Antibodies)-fibronectin (show FN1 Antibodies) matrix promotes fibronectin (show FN1 Antibodies) fibril deposition and requires syndecan-4 (show SDC4 Antibodies)/2 and {alpha}5{beta}1 integrin co-signaling.

  7. The role of syndecan-2 in regulation of actin-cytoskeletal organization of Lewis lung carcinoma-derived metastatic clones.

  8. Syndecan-2 mRNA transcripts are expressed by reactive astrocytes in the region surrounding the necrotic brain tissue, exhibiting peak levels at day 7 after cryo-injury.

  9. HSPG and LRP (show LRP1 Antibodies) together participate in VLDL clearance by means of a synergistic relationship.

  10. syndecan-2 has a role in the integration of signals from soluble and insoluble factors

Syndecan 2 (SDC2) Antigen Profile

Antigen Summary

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.

Alternative names and synonyms associated with Syndecan 2 (SDC2)

  • syndecan 2 (sdc2) antibody
  • syndecan 2 (SDC2) antibody
  • syndecan 2 (LOC100224966) antibody
  • syndecan 2 (Sdc2) antibody
  • 4833414L08Rik antibody
  • AA960457 antibody
  • cb440 antibody
  • CD362 antibody
  • HSPG antibody
  • Hspg1 antibody
  • Synd2 antibody
  • syndecan-2 antibody
  • zgc:103676 antibody

Protein level used designations for anti-Syndecan 2 (SDC2) Antibodies

syndecan-2 , syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) , syndecan 2 , cell surface-associated heparan sulfate proteoglycan 1 , fibroglycan , heparan sulfate proteoglycan 1, cell surface-associated , heparan sulfate proteoglycan core protein , syndecan proteoglycan 2 , HSPG , heparan sulfate proteoglycan 1, cell surface-associated (fibroglycan) , Ryudocan/syndecan 2 , SYND2

282667 Danio rerio
374102 Gallus gallus
477945 Canis lupus familiaris
549917 Xenopus (Silurana) tropicalis
100224966 Taeniopygia guttata
6383 Homo sapiens
15529 Mus musculus
25615 Rattus norvegicus
615785 Bos taurus
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