Browse our Versican Proteins (Vcan)

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Versican Proteins (Vcan)
On are 5 Versican (Vcan) Proteins from 3 different suppliers available. Additionally we are shipping Versican Antibodies (119) and Versican Kits (39) and many more products for this protein. A total of 164 Versican products are currently listed.
5430420N07Rik, 9430051N09, br146, Cspg2, cspg2a, cspg2b, dcan, DPEAAE, ERVR, fb99b07, GHAP, hdf, NG2, PG-M, PG-M(V0), PG-M(V1), sb:cb63, VCAN, versican, WGN, WGN1, wu:fb99b07, Xversican
list all proteins Gene Name GeneID UniProt
Vcan 1462 P13611
Vcan 13003  
Rat Vcan Vcan 114122 Q9ERB4

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Versican Proteins (Vcan) by Origin

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More Proteins for Versican Interaction Partners

Zebrafish Versican (Vcan) interaction partners

  1. The isolation and characterization of a cDNA encoding zebrafish dermacan, a novel member of hyaluronan (HA)-binding proteoglycans, which was termed after its characteristic expression in the zebrafish dermal bones.

Human Versican (Vcan) interaction partners

  1. Versican V0 and V1 isoforms were upregulated in the uterine leiomyomas of symptomatic versus asymptomatic women. Abundant cleaved versican was detected in leiomyoma and myometrium, as well as in myometrial and leiomyoma cell lines. VCAN siRNA did not effect cell proliferation, apoptosis, or smooth muscle markers, but reduced ESR1 (show ESR1 Proteins) and PR-A (show PGR Proteins) expression.

  2. Lumican (show LUM Proteins) and versican protein expression are associated with colorectal adenoma-to-carcinoma progression

  3. Removal or knockdown of versican may be a possible therapeutic strategy for increasing deposition of insoluble elastin (show ELN Proteins) and stimulating repair of elastic fibers in COPD (show ARCN1 Proteins) lung.

  4. human myeloma tumors displaying CD8 (show CD8A Proteins)(+) infiltration/aggregates underwent VCAN proteolysis at a site predicted to generate a glycosaminoglycan-bereft N-terminal fragment.

  5. versican decreases in follicular dermal papilla as an aging-associated change of human hair follicles

  6. Data indicate that serum versican levels were significantly decreased in polycystic ovary syndrome (PCOS) patients, and that serum ADAMTS-1 (show ADAMTS1 Proteins) (a disintegrin and metalloproteinase with thrombospondin motif-1) and versican levels were significantly and positively correlated with each other.

  7. the G1 domain of versican can regulate the organization of pericellular hyaluronan and affect phenotype of cultured human dermal fibroblasts

  8. Gene expression levels of three randomly selected DEGs (show DEGS1 Proteins), VCAN, COL5A1 and KCNJ16 (show KCNJ16 Proteins), were examined using RT-PCR in 10 ATC (show SRPK1 Proteins) samples.. angiogenesis was activated by the high expression of CTHRC1 (show CTHRC1 Proteins), VCAN and POSTN (show POSTN Proteins), providing necessary nutrition for tumor cells

  9. Results highlight an important role for versican in regulating the expression and assembly of elastin (show ELN Proteins) and the phenotype of leiomyosarcoma cells.

  10. Versican localizes to the nucleus in proliferating mesenchymal cells and suggest role in mitotic spindle organization during cell division.

Mouse (Murine) Versican (Vcan) interaction partners

  1. Loss of Versican is associated with reduced Lung Inflammatory Response.

  2. Results highlight an important role for versican in regulating the expression and assembly of elastin (show ELN Proteins) and the phenotype of leiomyosarcoma cells.

  3. Versican localizes to the nucleus in proliferating mesenchymal cells and suggest role in mitotic spindle organization during cell division.

  4. Pelvic irradiation increases versican expression in bladder and rectum.

  5. Versican V1 overexpression induces a myofibroblast-like phenotype in cultured fibroblasts.

  6. The data suggest that versican plays an important role in fundamental, overlapping cellular processes in lung development and infection.

  7. Our results show that versican released from glioma promotes tumor expansion through glioma-associated microglial/macrophage TLR2 signaling and subsequent expression of MT1-MMP (show MMP14 Proteins).

  8. Arylsulfatase B (show ARSB Proteins) regulates versican expression by galectin-3 (show LGALS3 Proteins) and AP-1 (show JUN Proteins) mediated transcriptional effects.

  9. Versican regulates the growth of leiomyosarcoma tumors.

  10. expression of Vcan mRNA splice form proteins alters heart morphology and cellular protein profiles

Cow (Bovine) Versican (Vcan) interaction partners

  1. Data show that expression of mRNAs for aggrecan (show ACAN Proteins), collagen type II, and versican were significantly effected by the intervention.

  2. Data show that biglycan (show BGN Proteins), collagen type I, collagen type II, decorin (show DCN Proteins), and versican were significantly affected by vibration duration, frequency, and amplitude.

Pig (Porcine) Versican (Vcan) interaction partners

  1. The relationship between hyaluronan synthesis and levels of versican, fibronectin (show FN1 Proteins) and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.

Versican (Vcan) Protein Profile

Protein Summary

This gene is a member of the aggrecan/versican proteoglycan family. The protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Mutations in this gene are the cause of Wagner syndrome type 1. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Versican (Vcan)

  • versican a (vcana)
  • versican b (vcanb)
  • versican (VCAN)
  • versican (vcan)
  • versican (Vcan)
  • versican (LOC100008666)
  • 5430420N07Rik protein
  • 9430051N09 protein
  • br146 protein
  • Cspg2 protein
  • cspg2a protein
  • cspg2b protein
  • dcan protein
  • DPEAAE protein
  • ERVR protein
  • fb99b07 protein
  • GHAP protein
  • hdf protein
  • NG2 protein
  • PG-M protein
  • PG-M(V0) protein
  • PG-M(V1) protein
  • sb:cb63 protein
  • VCAN protein
  • versican protein
  • WGN protein
  • WGN1 protein
  • wu:fb99b07 protein
  • Xversican protein

Protein level used designations for Versican Proteins (Vcan)

chondroitin sulfate proteoglycan 2a , chondroitin sulfate proteoglycan 2b , dermacan , chondroitin sulfate proteoglycan 2 (versican) , chondroitin sulfate proteoglycan 2 , versican , versican core protein-like , chondroitin sulfate proteoglycan core protein 2 , glial hyaluronate-binding protein , large fibroblast proteoglycan , versican core protein , versican proteoglycan , PG-M core protein , Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) , heart defect , GHAP , PG-M , proteoglycan

116993 Danio rerio
323465 Danio rerio
461766 Pan troglodytes
100101672 Xenopus (Silurana) tropicalis
445009 Canis lupus familiaris
100442387 Pongo abelii
100604867 Nomascus leucogenys
1462 Homo sapiens
13003 Mus musculus
114122 Rattus norvegicus
282662 Bos taurus
395565 Gallus gallus
488922 Canis lupus familiaris
397328 Sus scrofa
100727549 Cavia porcellus
100008666 Oryctolagus cuniculus
100294605 Ovis aries
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