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Browse our anti-XYLT2 (XYLT2) Antibodies

Full name:
anti-Xylosyltransferase II Antibodies (XYLT2)
On www.antibodies-online.com are 30 Xylosyltransferase II (XYLT2) Antibodies from 8 different suppliers available. Additionally we are shipping XYLT2 Kits (5) and XYLT2 Proteins (4) and many more products for this protein. A total of 43 XYLT2 products are currently listed.
Synonyms:
E030002B02Rik, MGC89331, PXYLT2, xt-II, XT2, xylt-II
list all antibodies Gene Name GeneID UniProt
XYLT2 64132 Q9H1B5
XYLT2 217119 Q9EPL0
XYLT2 64134  

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Most Popular Reactivities for anti-XYLT2 (XYLT2) Antibodies

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anti-Human XYLT2 Antibodies:

anti-Mouse (Murine) XYLT2 Antibodies:

anti-Rat (Rattus) XYLT2 Antibodies:

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Top referenced anti-XYLT2 Antibodies

  1. Dog (Canine) Polyclonal XYLT2 Primary Antibody for WB - ABIN2783857 : Casanova, Kuhn, Kleesiek, Götting: Heterologous expression and biochemical characterization of soluble human xylosyltransferase II. in Biochemical and biophysical research communications 2007 (PubMed)

More Antibodies against XYLT2 Interaction Partners

Human Xylosyltransferase II (XYLT2) interaction partners

  1. XYLT2 mutations cause a relatively distinct phenotype, the so-called spondyloocular syndrome.

  2. Homozygosity for frameshift mutations in XYLT2 result in a spondylo-ocular syndrome with bone fragility, cataracts, and hearing defects.

  3. Demonstrate that XT-II is the predominant isoenzyme responsible for XT activity in serum. The proof was performed using UDP-xylose (show XXYLT1 Antibodies) as the xylose donor, as well as the compound UDP-4-azido-4-deoxyxylose, which is a selective xylose donor for XT-I (show XYLT1 Antibodies).

  4. Seven XYLT2 promoter single nucleotide variants (SNVs) were identified and genotyped.

  5. The study identified and characterized for the first time the XYLT2 gene promoter region and transcription factors involved in its regulation.

  6. recombinant expression and cloning of active full-length xylosyltransferase I (XT-I (show XYLT1 Antibodies)) and characterization of subcellular localization of XT-I (show XYLT1 Antibodies) and XT-II

  7. demonstrate that a soluble form of human XT-II expressed in the xylosyltransferase-deficient pgsA-745 (S745) Chinese hamster ovary cell line is indeed capable of catalyzing the transfer of xylose to a variety of peptide substrates

  8. Our data show for the first time that XT-I (show XYLT1 Antibodies) and XT-II are xylosyltransferases with similar but not identical properties, pointing to their potential role in modulating the cellular proteoglycan (show Vcan Antibodies) pool.

  9. Our data show that a XYLT2 haplotype is associated with nephropathy in type 1 diabetic patients

  10. The deviation from Hardy-Weinberg equilibrium of two XYLT2 variants might be due to gene-phenotype associations which remain to be explored, as well as the possibility of gene-gene interactions.

Mouse (Murine) Xylosyltransferase II (XYLT2) interaction partners

  1. alterations in proteoglycans (PGs)concentrations can occur due to loss of XylT2, and that reduced PGs can induce cyst development

  2. the data from Xylt2 knock-out mice and mice with liver neoplasia show that liver is a significant source of serum XylT2 activity.

XYLT2 Antigen Profile

Antigen Summary

The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.

Alternative names and synonyms associated with XYLT2

  • xylosyltransferase II (xylt2) antibody
  • xylosyltransferase II (XYLT2) antibody
  • xylosyltransferase II (LOC100223613) antibody
  • xylosyltransferase II (LOC100342073) antibody
  • xylosyltransferase II (Xylt2) antibody
  • E030002B02Rik antibody
  • MGC89331 antibody
  • PXYLT2 antibody
  • xt-II antibody
  • XT2 antibody
  • xylt-II antibody

Protein level used designations for XYLT2

xylosyltransferase II , xylosyltransferase 2 , peptide O-xylosyltransferase 2 , proteoglycan core protein beta-D-xylosyltransferase , xylosyltransferase 2-like , UDP-D-xylose:core protein beta-D-xylosyltransferase , UDP-D-xylose:proteoglycan core protein beta-D-xylosyltransferase , peptide O-xylosyltransferase 1 , protein xylosyltransferase 2

GENE ID SPECIES
448400 Xenopus (Silurana) tropicalis
455118 Pan troglodytes
705139 Macaca mulatta
100223613 Taeniopygia guttata
100342073 Oryctolagus cuniculus
100385693 Callithrix jacchus
100459725 Pongo abelii
100600245 Nomascus leucogenys
414780 Gallus gallus
64132 Homo sapiens
493990 Canis lupus familiaris
493989 Bos taurus
217119 Mus musculus
64134 Rattus norvegicus
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