Browse our WISP1 Proteins (WISP1)

Full name:
WNT1 Inducible Signaling Pathway Protein 1 Proteins (WISP1)
On www.antibodies-online.com are 17 WNT1 Inducible Signaling Pathway Protein 1 (WISP1) Proteins from 9 different suppliers available. Additionally we are shipping WISP1 Antibodies (96) and WISP1 Kits (49) and many more products for this protein. A total of 171 WISP1 products are currently listed.
Synonyms:
AW146261, CCN4, Elm1, si:ch211-38f10.2, WISP-1, WISP1, WISP1c, WISP1i, WISP1tc
list all proteins Gene Name GeneID UniProt
WISP1 8840 O95388
WISP1 22402 O54775
WISP1 65154 Q99PP0

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WISP1 Proteins (WISP1) by Origin

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Top referenced WISP1 Proteins

  1. Human WISP1 Protein expressed in Escherichia coli (E. coli) - ABIN2667611 : Davies, Davies, Sanders, Parr, Torkington, Jiang: Differential expression of the CCN family member WISP-1, WISP-2 and WISP-3 in human colorectal cancer and the prognostic implications. in International journal of oncology 2010 (PubMed)
    Show all 8 references for 2667611

  2. Human WISP1 Protein expressed in Human Cells - ABIN2002857 : Pennica, Swanson, Welsh, Roy, Lawrence, Lee, Brush, Taneyhill, Deuel, Lew, Watanabe, Cohen, Melhem, Finley, Quirke, Goddard, Hillan, Gurney, Botstein, Levine: WISP genes are members of the connective tissue growth factor family that are up-regulated in wnt-1-transformed cells and aberrantly expressed in human colon tumors. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 5 references for 2002857

More Proteins for WISP1 Interaction Partners

Zebrafish WNT1 Inducible Signaling Pathway Protein 1 (WISP1) interaction partners

  1. Two paralogs of mammalian wisp1 genes were found in zebrafish.

Human WNT1 Inducible Signaling Pathway Protein 1 (WISP1) interaction partners

  1. results demonstrate that a joint effect of WISP1 rs2929970 with smoking as well as WISP1 rs16893344 with betel nut chewing causally contributes to the occurrence of OSCC. WISP1 polymorphism may serve as a marker or a therapeutic target in OSCC

  2. Taken together, our findings presented the first evidence that Wnt1-inducible signaling pathway protein-1 was upregulated in gastric cancer and acted as an oncogene (show RAB1A Proteins) by promoting proliferation, migration, and invasion in gastric cancer cells.

  3. findings reveal that WISP-1 enhances VEGF-A (show VEGFA Proteins) expression and angiogenesis through the FAK (show PTK2 Proteins)/JNK (show MAPK8 Proteins)/HIF-1alpha (show HIF1A Proteins) signaling pathways, as well as via down-regulation of miR (show MLXIP Proteins)-381 expression.

  4. Akt (show AKT1 Proteins) signaling pathway mediates WISP1-induced migration and proliferation of human VSMCs

  5. WISP1 is increased in IBD and contributes to the proinflammatory cascades in the gut (show GUSB Proteins).

  6. Data show that WNT1-inducible signaling pathway protein-1 (WISP)-1/CCN4 expression was correlated with vascular endothelial growth factor-C (VEGF-C (show VEGFC Proteins)) expression in Oral squamous cell carcinoma (OSCC) specimens.

  7. WISP1-induced IL-6 (show IL6 Proteins) expression contributes to the pro-proliferative effect on fibroblasts.

  8. WISP1 plays an important role in regulating proliferation and apoptosis of Jurkat cells.

  9. Study showed that DNA methylation (show HELLS Proteins) of the WISP1 promoter in the majority of the oral squamous cell carcinoma explains its expression regulation.

  10. CCN4 has a positive influence on chondrogenic differentiation by modulating the effects of TGF-beta3 (show TGFB3 Proteins).

Mouse (Murine) WNT1 Inducible Signaling Pathway Protein 1 (WISP1) interaction partners

  1. Upregulation of Wnt2 (show WNT2 Proteins) expression enhanced WISP-1 and promoted vascular smooth muscle cell migration and intimal thickening.

  2. One of the most striking new findings was up-regulation of mRNA for the matricellular protein WNT1-inducible signaling pathway protein 1 (CCN4) in metastatic cells; increased protein expression was verified by immunoblotting and immunocytochemistr

  3. WISP1 might contribute to hepatic ischemia reperfusion injury in mice and possibly depends on TLR4 (show TLR4 Proteins)/TRIF (show RNF138 Proteins) signaling.

  4. CCN4 has a positive influence on chondrogenic differentiation by modulating the effects of TGF-beta3 (show TGFB3 Proteins).

  5. the Bmp3 (show BMP3 Proteins)/Wisp1 signaling pathway play a key role in mesenchymal stem cell proliferation, and consequently adipogenesis.

  6. the Wisp1-integrin beta6 pathway is inhibited by RGD peptides in septic mice, which protects against acute lung injury

  7. WISP1 is a novel regulator of bone turnover and Wnt (show WNT2 Proteins) signaling

  8. The data suggest that WISP1 may play a role in linking obesity to inflammation and insulin (show INS Proteins) resistance and could be a novel therapeutic target for obesity.

  9. Wnt5a (show WNT5A Proteins)-induced Wnt1 (show WNT1 Proteins)-inducible secreted protein-1 suppresses vascular smooth muscle cell apoptosis induced by oxidative stress.

  10. Notch1 (show NOTCH1 Proteins)-induced WISP-1 expression appeared to be Wnt11 (show WNT11 Proteins)-dependent, but Wnt1 (show WNT1 Proteins)-independent

WISP1 Protein Profile

Protein Summary

This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83% identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified.

Alternative names and synonyms associated with WISP1

  • WNT1 inducible signaling pathway protein 1 (WISP1)
  • WNT1 inducible signaling pathway protein 1 (LOC100220694)
  • WNT1 inducible signaling pathway protein 1a (wisp1a)
  • WNT1 induced secreted protein 1 (LOC100009043)
  • WNT1 inducible signaling pathway protein 1 (Wisp1)
  • WNT1-inducible-signaling pathway protein 1-like (LOC100627044)
  • AW146261 protein
  • CCN4 protein
  • Elm1 protein
  • si:ch211-38f10.2 protein
  • WISP-1 protein
  • WISP1 protein
  • WISP1c protein
  • WISP1i protein
  • WISP1tc protein

Protein level used designations for WISP1

WNT1 inducible signaling pathway protein 1 , wisp1 , zWISP1-c19 , CCN family member 4 , WNT1 induced secreted protein 1 , WNT1-inducible-signaling pathway protein 1 , Wnt-1 inducible signaling pathway protein 1 , ELM-1 , WISP-1 , Wnt-1-induced secreted protein

GENE ID SPECIES
472862 Pan troglodytes
697624 Macaca mulatta
100081234 Ornithorhynchus anatinus
100220694 Taeniopygia guttata
560713 Danio rerio
100009043 Oryctolagus cuniculus
8840 Homo sapiens
22402 Mus musculus
65154 Rattus norvegicus
100729064 Cavia porcellus
482048 Canis lupus familiaris
539163 Bos taurus
420322 Gallus gallus
100627044 Sus scrofa
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