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Human Monoclonal HHIP Primary Antibody for WB - ABIN396574
Pillai, Kong, Edwards, Cho, Anderson, Coxson, Lomas, Silverman,: Loci identified by genome-wide association studies influence different disease-related phenotypes in chronic obstructive pulmonary disease. in American journal of respiratory and critical care medicine 2010
Show all 5 references for ABIN396574
Human Monoclonal HHIP Primary Antibody for IHC (p), IP - ABIN566261
Shi, Moura, Opitz, Soltermann, Rehrauer, Thies, Weder, Stahel, Felley-Bosco: Role of hedgehog signaling in malignant pleural mesothelioma. in Clinical cancer research : an official journal of the American Association for Cancer Research 2012
Hhip regulates muscle development both by sequestering Hedgehog (show SHH Antibodies) and by modulating localization of Smoothened (show SMO Antibodies)
Localized expression of Xhip may counteract certain overlapping signaling activities, which inhibit the induction of olfactory and lens placodes.
HHIP expression and Gli1 (show GLI1 Antibodies) expression were independent prognostic factors in glioblastoma.
HHIP - candidate gene for Chronic Obstructive Pulmonary Disease identified by Genome-wide association studies.
Shh (show SHH Antibodies)-mediated degradation of Hhip allows cell autonomous and non-cell autonomous Shh (show SHH Antibodies) signaling.
HHIP might be a diagnostic or prognostic marker in glioma and help to the detection of these tumors in early stages of disease.
HHIP is located within genes previously associated with chronic obstructive pulmonary disease susceptibility.
Genetic variants in HHIP are associated with FEV1 in subjects with chronic obstructive pulmonary disease.
The data demonstrated that loss of expression of HHIP and PTCH (show PTCH1 Antibodies) is associated with the methylation of gene promoters
We show that GPC3 (show GPC3 Antibodies), an hepatocellular carcinoma biomarker and Hh mediator, regulates human stellate cell viability by regulating Hh signaling.
Data indicate that the Shh (show SHH Antibodies) signaling transduction is facilitated by binding of Shh (show SHH Antibodies) to its receptor protein, Ptch (show PTCH1 Antibodies), and show the complex structure of Shh (show SHH Antibodies)-Hhip.
our study suggests that the HHIP gene may be involved in COPD susceptibility in Chinese Han population.
The HHIP gene that is known to be associated with stature in humans was strongly associated with direct calving difficulty in the present study.
PTCH1 (show PTCH1 Antibodies), PTCH2 (show PTCH2 Antibodies) and HHIP1 all contribute to ligand-dependent antagonism of sonic hedgehog (show SHH Antibodies) signaling.
Estradiol improves the recovery of injured nerves by downregulating the Shh (show SHH Antibodies) inhibitor hedgehog-interacting protein and increasing Shh (show SHH Antibodies)-induced angiogenesis.
hedgehog (show SHH Antibodies) antagonists patched 1 (show PTCH1 Antibodies) and Hhip1 have roels in growth and pattern of the mammalian neural tube
hypothesis for a functional link between nitric oxide and Shh (show SHH Antibodies) signaling and for a nonredundant role of Hip and Ptc1 (show PTCH1 Antibodies) in the adult brain
These data indicate that Hh signaling plays a role in adult gut (show GUSB Antibodies) epithelial homeostasis by regulating epithelial cell migration from crypt to villus tip and by enhancing apoptosis.
These results strongly suggest that GSK3beta (show GSK3b Antibodies) phosphorylates Sufu (show SUFUH Antibodies) to positively regulate Hedgehog (show SHH Antibodies) signaling in mammalian cells.
This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.
, hedgehog-interacting protein
, hedgehog interacting protein
, hedgehog-interacting protein-like
, Hedgehog-interacting protein-like