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These data suggest that GLI (show GLI1 Proteins) interactions with KIF3A (show KIF3A Proteins)-KIF3B-KAP3 (show KIFAP3 Proteins) complexes are essential for proper GLI (show GLI1 Proteins) transcriptional activity.
both motor domains of KIF3A (show KIF3A Proteins)/B coordinate for processive motility and move at different speeds
Results suggest that KIF3B expression was upregulated in HCC (show FAM126A Proteins) tumor tissues and proliferating HCC (show FAM126A Proteins) cells, and an increasd KIF3B expression was associated with poor overall survival.
KIF3B is involved in the trafficking of kAE1 (show OSGEP Proteins) to the plasma membrane of human kidney alpha-intercalated cells.
Interaction with KIF3B alters CLC-5 (show CLCN5 Proteins) cell surface expression, chloride current, and alters albumin (show ALB Proteins) endocytosis. Interaction with KIF3B facilitates microtubular transport and endocytosis of CLC-5 (show CLCN5 Proteins)-containing vesicles away from cell surface.
Interaction of KIF3A (show KIF3A Proteins)/3B with KAP3 (show KIFAP3 Proteins) may be important for the proper progression of mitosis.
kinesin-2 is a linker between polycystin-2(PC2) and fibrocystin and mediates the regulation of PC2 channel function by fibrocystin
Rip11 (show RAB11FIP5 Proteins)/FIP5-kinesin-II (show KLC1 Proteins) complex plays a key role in the routing of internalized receptors through the perinuclear recycling endosomes.
Data indicate that p0071 and Ect2 are transported via distinct motors and identify a novel pathway implicating KIF3 in the regulation of actin organization during cytokinesis
KIF3AB exhibits novel ATPase activity.
our data suggest that RNF33 (show TRIM60 Proteins) most likely interacts with KIF3A (show KIF3A Proteins)-KIF3B independent of the adaptor kinesin-associated protein KAP3 (show KIFAP3 Proteins)
The protein encoded by this gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily.
kinesin-like protein KIF3B
, microtubule plus end-directed kinesin motor 3B