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Browse our Prokineticin Receptor 2 Proteins (PROKR2)

Full name:
Prokineticin Receptor 2 Proteins (PROKR2)
On www.antibodies-online.com are 3 Prokineticin Receptor 2 (PROKR2) Proteins from 2 different suppliers available. Additionally we are shipping Prokineticin Receptor 2 Antibodies (47) and Prokineticin Receptor 2 Kits (22) and many more products for this protein. A total of 77 Prokineticin Receptor 2 products are currently listed.
Synonyms:
B830005M06Rik, dJ680N4.3, EG-VEGRF2, Gpcr73l1, GPR73b, Gpr73l1, GPRg2, HH3, KAL3, PKR2, PRKAR2
list all proteins Gene Name GeneID UniProt
PROKR2 128674 Q8NFJ6
PROKR2 246313 Q8K458
Rat PROKR2 PROKR2 192649 Q8R415

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Prokineticin Receptor 2 Proteins (PROKR2) by Origin

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More Proteins for Prokineticin Receptor 2 Interaction Partners

Human Prokineticin Receptor 2 (PROKR2) interaction partners

  1. Data suggest that prokineticins (PROK1 (show Prok1 Proteins) and PROK2 (show PROK2 Proteins)) and prokineticin receptors (PROKR1 (show PROKR1 Proteins) and PROKR2) act as main regulators of physiological functions of ovary, uterus, placenta, and testis. [REVIEW]

  2. High PK-R2 expression is associated with colorectal cancer.

  3. PROKR2 may play a role in susceptibility of pituitary stalk interruption syndrome

  4. Prkar2a (show PRKAR2A Proteins) deficiency predisposes to hematopoietic malignancies in vivo. RIIalpha's likely association with HS and DLBCL was hitherto unrecognized and may lead to better understanding of these rare neoplasms.

  5. Disruption of Snapin (show SNAPIN Proteins)-PKR2 interaction did not affect PKR2 signaling, but increased the ligand-induced degradation, implying a role of Snapin (show SNAPIN Proteins) in the trafficking of PKR2.

  6. we demonstrate that neurochondrin has strong isoform selectivity towards the RIIa subunit of PKA with nanomolar affinity

  7. PROKR2 expression in human fetal ovary remained unchanged throughout gestation.

  8. EG-VEGF (show Prok1 Proteins), BV8 (show PROK2 Proteins), and PROKR2 gene expression is approximately five, four, and two times higher in cystic fibrosis (show S100A8 Proteins) lungs compared with controls.

  9. PKR2 protomers form type II dimers involving TMs (show TYMS Proteins) 4 and 5, with a role for TM5 in modulation of PKR2 function.

  10. Results show that mouse Prkar1a (show PRKAR1A Proteins) and human PRKAR2A (show PRKAR2A Proteins) exhibited a dynamic spatio-temporal expression in tooth development, whereas neither human PRKAR1A (show PRKAR1A Proteins) nor mouse Prkar2a (show PRKAR2A Proteins) showed their expression in odontogenesis.

Mouse (Murine) Prokineticin Receptor 2 (PROKR2) interaction partners

  1. Data show that the prokineticins and their receptors PROK2 (show PROK2 Proteins), PKR1 (show PROKR1 Proteins) and PKR2 contributes to altered sensitivity in diabetic neuropathy and its inhibition blocked both allodynia and inflammatory events underlying disease.

  2. Studies indicate PK2 (show PROK2 Proteins) signaling is required for the maintenance of normal female estrous cycles.

  3. We sought to clarify the role of PROKR2 in hypothalamopituitary development through analysis of Prokr2(-/-) mice.

  4. Prokr2 is specifically expressed in the XY gonads during sex determination and fetal sexual differentiation, and knockout mice display a variable degree of compromised vasculature in the fetal testes

  5. The functional characteristics of coronary endothelial cells depend on the expression of PKR1 (show PROKR1 Proteins) and PKR2 levels and the divergent signaling pathways used by these receptors.

  6. prokineticin 2 (show PROK2 Proteins) is expressed in neurons of the mouse suprachiasmatic nucleus

  7. Phenotypic analysis indicated that not Pkr1 (show PROKR1 Proteins)(-/-)but Pkr2(-/-)mice exhibited hypoplasia of the olfactory bulb.

  8. PKR2 expression was maintained over 10.5dpc with both trophoblastic and endothelial cell localisations in mice.

  9. Important role for Prokr2 in olfactory bulb neurogenesis.

  10. Prokineticin 2 (show PROK2 Proteins) polypeptide (Prokr2) signaling plays a role in hypothalamic regulation of energy balance, and loss of this pathway results in physiological and behavioral responses normally only detected when mice are in negative energy balance.

Prokineticin Receptor 2 (PROKR2) Protein Profile

Protein Summary

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).

Alternative names and synonyms associated with Prokineticin Receptor 2 (PROKR2)

  • prokineticin receptor 2 (PROKR2)
  • prokineticin receptor 2 (Prokr2)
  • protein kinase, cAMP-dependent, regulatory, type II, alpha (PRKAR2A)
  • B830005M06Rik protein
  • dJ680N4.3 protein
  • EG-VEGRF2 protein
  • Gpcr73l1 protein
  • GPR73b protein
  • Gpr73l1 protein
  • GPRg2 protein
  • HH3 protein
  • KAL3 protein
  • PKR2 protein
  • PRKAR2 protein

Protein level used designations for PROKR2

prokineticin receptor 2 , prokineticin receptor 2-like , G protein-coupled receptor 73-like 1 , PK-R2 , G-protein coupled receptor 73-like 1 , G protein-coupled receptor I5E , G-protein coupled receptor I5E , cAMP-dependent protein kinase regulatory subunit RII alpha , cAMP-dependent protein kinase type II-alpha regulatory subunit , protein kinase A, RII-alpha subunit

GENE ID SPECIES
458082 Pan troglodytes
100052008 Equus caballus
100401606 Callithrix jacchus
100550224 Meleagris gallopavo
100593640 Nomascus leucogenys
128674 Homo sapiens
246313 Mus musculus
192649 Rattus norvegicus
100339634 Oryctolagus cuniculus
100713590 Cavia porcellus
100625714 Sus scrofa
282431 Bos taurus
485779 Canis lupus familiaris
421263 Gallus gallus
101114889 Ovis aries
5576 Homo sapiens
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