Browse our anti-SUFUH (SUFUH) Antibodies

Full name:
anti-Suppressor of Fused Homolog (Drosophila) Antibodies (SUFUH)
On are 52 Suppressor of Fused Homolog (Drosophila) (SUFUH) Antibodies from 16 different suppliers available. Additionally we are shipping SUFUH Proteins (7) and many more products for this protein. A total of 66 SUFUH products are currently listed.
2810026F04Rik, b2b273Clo, CG6054, Dmel\\CG6054, dre, fi39e05, PRO1280, Su(fu), sufu, SUFUH, SUFUXL, wu:fi39e05, Xsufu
list all antibodies Gene Name GeneID UniProt
SUFUH 51684 Q9UMX1
SUFUH 24069 Q9Z0P7
SUFUH 361769  

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Top referenced anti-SUFUH Antibodies

  1. Human Polyclonal SUFUH Primary Antibody for WB - ABIN616041 : Zimmern, Kobashi, Lemack: Outcome measure for stress urinary incontinence treatment (OMIT): results of two society of urodynamics and female urology (SUFU) surveys. in Neurourology and urodynamics 2010 (PubMed)
    Show all 2 references for 616041

  2. Cow (Bovine) Polyclonal SUFUH Primary Antibody for WB - ABIN2777710 : Lee, Deng, Wang, Yang: MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

More Antibodies against SUFUH Interaction Partners

Fruit Fly (Drosophila melanogaster) Suppressor of Fused Homolog (Drosophila) (SUFUH) interaction partners

  1. A Comparison of Ci/Gli (show GLI1 Antibodies) Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog (show SHH Antibodies) Response

  2. Sufu can sequester Ci/Gli (show GLI1 Antibodies) in the cytoplasm through binding to an N-terminal site while inhibiting Ci/Gli (show GLI1 Antibodies) activity in the nucleus depending on a C-terminal Sufu-interacting site.

  3. Drosophila Hedgehog (show SHH Antibodies) signaling promotes downregulation of Su(fu) through its target protein HIB (Hh-induced BTB protein).

  4. Suppressor of fused (Sufu) opposes Trn-mediated Ci nuclear import by masking its PY-nuclear localization sequence.

  5. The 'closed' form of Sufu is stabilized by Gli (show GLI1 Antibodies) binding and inhibited by Hh treatment, whereas the 'open' state of Sufu is promoted by Gli (show GLI1 Antibodies)-dissociation and Hh signaling.

  6. Su(fu) causes the Rdx (show RDX Antibodies) switch between two mchanisms of Cubitus interruptus regulation.

  7. Suppressor of Fused represses Gli (show GLI1 Antibodies)-mediated transcription by recruiting the SAP18 (show SAP18 Antibodies)-mSin3 corepressor complex.

  8. Differential Hh target gene regulation can be accomplished by differential sensitivity of Cos2 (show KIF7 Antibodies) and Su(Fu) to Hh.

  9. Su(fu) protein levels and isoforms are crucial for the modulation of the different Ci states that control Hh target gene expression.

Xenopus laevis Suppressor of Fused Homolog (Drosophila) (SUFUH) interaction partners

  1. Sufu may act as a common regulator of Hh and Wnt (show WNT2 Antibodies) signaling and contribute to intertwining the two pathways.

Human Suppressor of Fused Homolog (Drosophila) (SUFUH) interaction partners

  1. miRNA-194 is oncogenic and promotes gastric cancer cell proliferation and migration by activating Wnt (show WNT2 Antibodies) signaling, at least in part, via suppression of SUFU.

  2. SUFU's role in Hedgehog (show SHH Antibodies) signaling, tumor progression, and highlight a way in which BCCs can arise

  3. In summary, these findings reveal Fbxl17 (show FBXL17 Antibodies) as a novel regulator of the Hedgehog (show SHH Antibodies) signaling pathway and highlight the perturbation of the Fbxl17 (show FBXL17 Antibodies)-Sufu axis in the pathogenesis of medulloblastoma.

  4. there was a positive correlation between VDR (show CYP27B1 Antibodies) status and the expression of Suppressor of fused gene (SuFu), a hedgehog (show SHH Antibodies) pathway inhibitor. miR (show MLXIP Antibodies)-214 on the other hand suppressed SuFu protein expression.

  5. The data indicate that there exists a novel transcript variant of SUFU which can be transcribed and translated into corresponding protein and its transcription is related with metastasis of lymph nodes in pancreatic ductal adenocarcinoma.

  6. We showed that the supplementation of the osteogenic differentiation medium with PTHrP (show PTHLH Antibodies) inhibited the alkaline phosphatase activity and the expression of the transcription factor DLX3 (show DLX3 Antibodies), but the depletion of PTHrP (show PTHLH Antibodies) did not support the differentiation of DFCs.We showed that SUFU (Suppressor Of Fused Homolog) was not regulated during the osteogenic differentiation in DFCs

  7. This study uncovers a previously unappreciated miR (show MLXIP Antibodies)-214-Sufu pathway in controlling EMT (show ITK Antibodies) and metastasis of lung adenocarcinoma.

  8. A germline SUFU mutation was present in a patient with MHIBCC, and additional acquired SUFU mutations underlie the development of infundibulocystic basal cell carcinomas

  9. SUFU germline polymorphism is associated with acute GVHD

  10. Sufu has a role in repressing Gli1 (show GLI1 Antibodies) transcription and nuclear accumulation, inhibiting glioma cell proliferation, invasion and vasculogenic mimicry, improving glioma chemo-sensitivity and prognosis

Zebrafish Suppressor of Fused Homolog (Drosophila) (SUFUH) interaction partners

  1. Through regulation of su(fu), miR (show MYLIP Antibodies)-214 enables precise specification of muscle cell types by sharpening cellular responses to Hedgehog (show SHH Antibodies).

Mouse (Murine) Suppressor of Fused Homolog (Drosophila) (SUFUH) interaction partners

  1. Sufu is upregulated in active Shh (show SHH Antibodies) responding tissues and accompanies Gli (show GLI1 Antibodies) activators translocating into and Gli (show GLI1 Antibodies) repressors out of the nucleus.

  2. Sufu deletion early in embryogenesis resulted in unstable Gli2 (show GLI2 Antibodies) and Gli3 (show GLI3 Antibodies) activity, leading to the ectopic activation of Shh (show SHH Antibodies) signaling.

  3. Thus, we provide evidence that Sufu is involved in the genetic network that restricts the posterior expression of Gli2 (show GLI2 Antibodies)/3/Hand2 (show HAND2 Antibodies) and Gremlin (show GREM1 Antibodies)/Fgf in limb bud patterning.

  4. Results showed that the Thr396 residue of Sufu is specifically required for regulation of Gli3 (show GLI3 Antibodies) but not Gli2 (show GLI2 Antibodies) implying a novel Sufu-mediated mechanism in which Gli2 (show GLI2 Antibodies) activator and Gli3 (show GLI3 Antibodies) repressor are differentially regulated.

  5. findings demonstrate that perturbations of Sufu and Kif7 (show KIF7 Antibodies) affect Gli (show GLI1 Antibodies) activity and recapitulate the full spectrum of vertebrate limb defects, ranging from severe truncation to polydactyly.

  6. Hh signaling results in reduced Sufu protein levels and Sufu dissociation from Gli (show GLI1 Antibodies) proteins in the nucleus, highlighting critical functions of Sufu in the nucleus.

  7. Data suggest nuclear entry of GLI1 (glioma-associated oncogene homolog (show GLI1 Antibodies), a zinc finger protein) is regulated by unique mechanism via mutually exclusive binding by its nuclear import factor IMB1 (show KPNB1 Antibodies) (importin (show KPNA4 Antibodies) B1) and SuFu (suppressor of fused protein).

  8. Differential regulation of Gli (show GLI1 Antibodies) proteins by Sufu in the lung affects PDGF (show PDGFA Antibodies) signaling and myofibroblast development.

  9. Evc (show EVC Antibodies) silencing in Sufu(-/-) cells attenuated the output of the Hh pathway, suggesting that Evc (show EVC Antibodies)/Evc2 (show EVC2 Antibodies) also promote Hh signaling in the absence of Sufu

  10. Sufu acts universally as a negative regulator of Hedgehog (show SHH Antibodies) signaling.

SUFUH Antigen Profile

Antigen Summary

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with SUFUH

  • Suppressor of fused (Su(fu)) antibody
  • suppressor of fused homolog (sufu) antibody
  • suppressor of fused homolog (Drosophila) (SUFU) antibody
  • suppressor of fused homolog (Drosophila) (sufu) antibody
  • suppressor of fused homolog (Drosophila) (Sufu) antibody
  • 2810026F04Rik antibody
  • b2b273Clo antibody
  • CG6054 antibody
  • Dmel\\CG6054 antibody
  • dre antibody
  • fi39e05 antibody
  • PRO1280 antibody
  • Su(fu) antibody
  • sufu antibody
  • SUFUH antibody
  • SUFUXL antibody
  • wu:fi39e05 antibody
  • Xsufu antibody

Protein level used designations for SUFUH

CG6054-PA , Su(fu)-PA , suppressor of fused , suppressor of fused homolog , dreumes

41565 Drosophila melanogaster
444442 Xenopus laevis
51684 Homo sapiens
100001615 Danio rerio
374118 Gallus gallus
608531 Canis lupus familiaris
535067 Bos taurus
24069 Mus musculus
361769 Rattus norvegicus
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