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Browse our TRAF3IP1 Proteins (TRAF3IP1)

Full name:
TNF Receptor-Associated Factor 3 Interacting Protein 1 Proteins (TRAF3IP1)
On www.antibodies-online.com are 5 TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1) Proteins from 3 different suppliers available. Additionally we are shipping TRAF3IP1 Antibodies (60) and many more products for this protein. A total of 74 TRAF3IP1 products are currently listed.
Synonyms:
3930402D05Rik, AU041749, Elipsa, MGC184660, MIP-T3, MIPT3, zgc:63522
list all proteins Gene Name GeneID UniProt
TRAF3IP1 26146 Q8TDR0
Rat TRAF3IP1 TRAF3IP1 363286 Q5XIN3
TRAF3IP1 74019 Q149C2

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TRAF3IP1 Proteins (TRAF3IP1) by Origin

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More Proteins for TRAF3IP1 Interaction Partners

Zebrafish TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1) interaction partners

  1. Traf3ip1 is a negative regulator of microtubule stability. Microtubule defects caused by traf3ip1 KO are associated with altered epithelialization/polarity in renal cells and with pronephric cysts and microphthalmia in zebrafish embryos.

  2. Data show that elipsa encodes a coiled-coil polypeptide that localizes to cilia, and that it interacts genetically with Rabaptin5, a well-studied regulator of endocytosis, which in turn interacts with Rab8 (show RAB8A Proteins), a small GTPase (show RACGAP1 Proteins), known to localize to cilia.

Human TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1) interaction partners

  1. Mutations in TRAF3IP1 are identified in patients with nephronophthisis and retinal degeneration. The identified mutations result in mild ciliary defects in patients and reveal a role of IFT54 as a negative regulator of microtubule stability via MAP4 (show MAP4 Proteins).

  2. MIP-T3 functions as a negative regulator of the innate type I interferon (show IFNA Proteins) response by preventing TRAF3 (show TRAF3 Proteins) from forming protein complexes with critical downstream transducers and effectors of antiviral response.

  3. Data show that MIP-T3 protein level is highly regulated; mainly mediated by the ubiquitin-proteasome system.

  4. The interaction of MIP-T3 with both actin filaments and microtubule suggested that MIP-T3 may play an important role in regulation of cytoskeleton dynamics in cells.

  5. These results suggest that MIP-T3 is a novel inhibitor of IL-13 (show IL13 Proteins) signaling and may be a useful molecule in ameliorating various conditions in which IL-13 (show IL13 Proteins) plays a central role.

Mouse (Murine) TNF Receptor-Associated Factor 3 Interacting Protein 1 (TRAF3IP1) interaction partners

  1. Homozygous Traf3ip1 mutants are not viable and have both neural developmental defects and polydactyly, phenotypes typical of mutants with ciliary assembly defects.

  2. Data show that overexpression of IFT54/Traf3ip1 displaces IFT20 (show IFT20 Proteins) from the Golgi apparatus. IFT54s effect on IFT20 (show IFT20 Proteins) is a dominant negative phenotype caused by its overexpression.

TRAF3IP1 Protein Profile

Protein Summary

Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules (By similarity).

Alternative names and synonyms associated with TRAF3IP1

  • TNF receptor-associated factor 3 interacting protein 1 (traf3ip1)
  • TNF receptor-associated factor 3 interacting protein 1 (TRAF3IP1)
  • TNF receptor-associated factor 3 interacting protein 1 (Traf3ip1)
  • TRAF3 interacting protein 1 (Traf3ip1)
  • 3930402D05Rik protein
  • AU041749 protein
  • Elipsa protein
  • MGC184660 protein
  • MIP-T3 protein
  • MIPT3 protein
  • zgc:63522 protein

Protein level used designations for TRAF3IP1

TRAF3-interacting protein 1 , eli , mipt3 , TNF receptor-associated factor 3 interacting protein 1 , TRAF3-interacting protein 1-like , interleukin 13 receptor alpha 1-binding protein-1 , interleukin-13 receptor alpha 1-binding protein 1 , microtubule interacting protein that associates with TRAF3 , microtubule-interacting protein associated with TRAF3 , microtubule-interacting protein that associates with TRAF3

GENE ID SPECIES
393572 Danio rerio
504984 Bos taurus
607339 Canis lupus familiaris
696594 Macaca mulatta
771149 Gallus gallus
779507 Xenopus (Silurana) tropicalis
100009843 Monodelphis domestica
100066684 Equus caballus
100411296 Callithrix jacchus
100434239 Pongo abelii
742394 Pan troglodytes
100079320 Ornithorhynchus anatinus
100597393 Nomascus leucogenys
26146 Homo sapiens
363286 Rattus norvegicus
74019 Mus musculus
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