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Browse our OAS1B (OAS1B) ELISA Kits

Full name:
2'-5' Oligoadenylate Synthetase 1B ELISA Kits (OAS1B)
On are 0 2'-5' Oligoadenylate Synthetase 1B (OAS1B) ELISA Kits from different suppliers available. Additionally we are shipping and and many more products for this protein. A total of 3 OAS1B products are currently listed.
Flv, L1, Mmu-L1, Oas1, Oias-2, Oias2, Wnv
list all ELISA KIts Gene Name GeneID UniProt
Mouse OAS1B OAS1B 23961 Q60856

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More ELISA Kits for OAS1B Interaction Partners

Mouse (Murine) 2'-5' Oligoadenylate Synthetase 1B (OAS1B) interaction partners

  1. Oas1b is part of a complex located in the ER and that ABCF3 is a component of the Flv(r)-mediated resistance mechanism.

  2. Activation of Oas1b gene expression by type I IFN requires only STAT2 (show STAT2 ELISA Kits), not STAT1 (show STAT1 ELISA Kits).

  3. Oas1b inhibits flavivirus replication by an alternative mechanism that overrides the proviral effect of reducing 2-5A accumulation and RNase L (show RNASEL ELISA Kits) activation.

  4. A positional cloning strategy was used to identify 22 genes from the Flv gene interval including 10 members of the 2'-5'-oligoadenylate synthetase gene family.

OAS1B Antigen Profile

Antigen Summary

This gene is a member of the 2'-5' oligoA synthetase family, which are clustered on chromosome 5. The encoded protein functions in the interferon-regulated OAS/RNase L system, which mediates RNA decay as part of the innate antiviral immunity pathway. The protein binds double-stranded RNA and oligomerizes ATP, which activate the single-stranded RNA cleavage enzyme RNase L. This protein mediates resistance to flaviviruses such as West Nile virus. The majority of wild mouse strains produce a functional protein and are resistant to flavivirus infection, whereas some inbred mouse strains including the strain of the reference genome, C57BL/6J, contain a premature stop codon that inactivates this gene product.

Alternative names and synonyms associated with OAS1B

  • 2'-5' oligoadenylate synthetase 1B (Oas1b) Elisa Kit
  • Flv Elisa Kit
  • L1 Elisa Kit
  • Mmu-L1 Elisa Kit
  • Oas1 Elisa Kit
  • Oias-2 Elisa Kit
  • Oias2 Elisa Kit
  • Wnv Elisa Kit

Protein level used designations for OAS1B

(2-5')oligo(A) synthase 1B , (2-5')oligo(A) synthetase 1b , 2',5'-oligoadenylate synthetase-like 1 , 2'-5'-oligoadenylate synthase 1B , 2'-5'-oligoadenylate synthase-like protein 1 , 2'-5'-oligoadenylate synthetase-like protein 1 , 2-5A synthase 1B , 2-5A synthetase 1B , Flavivirus resistance , inactive 2'-5'-oligoadenylate synthase 1B

23961 Mus musculus
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