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Browse our OAS2 Proteins (OAS2)

Full name:
2'-5'-Oligoadenylate Synthetase 2, 69/71kDa Proteins (OAS2)
On www.antibodies-online.com are 3 2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) Proteins from 2 different suppliers available. Additionally we are shipping OAS2 Antibodies (77) and OAS2 Kits (6) and many more products for this protein. A total of 93 OAS2 products are currently listed.
Synonyms:
Oasl11
list all proteins Gene Name GeneID UniProt
Rat OAS2 OAS2 363938  
OAS2 246728  
OAS2 4939 P29728

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OAS2 Proteins (OAS2) by Origin

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More Proteins for OAS2 Interaction Partners

Human 2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2) interaction partners

  1. Suggest 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-zeta (show CD247 Proteins) chain down-regulation via caspase-3 (show CASP3 Proteins) activation in oral cancer.

  2. Data obtained suggest that the OAS2 rs1293762 and CD209 (show CD209 Proteins) rs2287886 SNPs are associated with predisposition to chronic hepatitis C in Russian population.

  3. Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL (show OASL Proteins) and OAS2 genes.

  4. The results suggest that OAS1 (show OAS1 Proteins)-OAS3-OAS2 haplotypes are associated with differential susceptibility to clinical outcomes of dengue infection.

  5. The data suggest a possible association between OAS2 and OAS3 single nucleotide polymorphisms and the outcome of tick-borne encephalitis virus infection in a Russian population.

  6. 2'-5'-oligoadenylate synthetase type 2 (OAS2), a dsRNA binding protein involved in the pathway that activates RNase-L, is identified as a new binding partner for NOD2.

OAS2 Protein Profile

Protein Summary

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternative names and synonyms associated with OAS2

  • 2'-5'-oligoadenylate synthetase 2, 69/71kDa (OAS2)
  • 2'-5' oligoadenylate synthetase 2 (Oas2)
  • Oasl11 protein

Protein level used designations for OAS2

2'-5'-oligoadenylate synthetase 2, 69/71kDa , 2'-5'-oligoadenylate synthase 2-like , (2-5')oligo(A) synthase 2 , 2'-5'-oligoadenylate synthase 2 , 2-5A synthase 2 , 2',5'-oligoadenylate synthetase-like 11 , 2'-5' oligoadenylate synthetase-like 11 , 2,5-oligoadenylate synthetase-like 11 , (2'-5')oligo(A) synthetase 2 , p69 OAS / p71 OAS , 2'-5' oligoadenylate synthetase 2

GENE ID SPECIES
100468112 Ailuropoda melanoleuca
100588209 Nomascus leucogenys
363938 Rattus norvegicus
246728 Mus musculus
4939 Homo sapiens
611051 Canis lupus familiaris
595128 Sus scrofa
529660 Bos taurus
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