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anti-Human OAS3 Antibodies:
anti-Mouse (Murine) OAS3 Antibodies:
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Human Polyclonal OAS3 Primary Antibody for WB - ABIN390166
Ito, Shichijo, Tsuda, Ochi, Harashima, Saito, Itoh: Molecular basis of T cell-mediated recognition of pancreatic cancer cells. in Cancer research 2001
Show all 4 Pubmed References
The study findings suggest that the OAS3 rs1859330 G/A genetic polymorphism is associated with the severity of enterovirus 71 (EV71) infection, and that the A allele is a risk factor for the development of severe EV71 infection.
we characterized the functional consequences of the Neandertal haplotype in the transcriptional regulation of OAS (show SMOC1 Antibodies) genes at baseline and infected conditions. We found that cells from people with the Neandertal-like haplotype express lower levels of OAS3 upon infection, as well as distinct isoforms of OAS1 (show OAS1 Antibodies) and OAS2 (show OAS2 Antibodies)
Here we report, to our knowledge, the first analysis of nuclear signal import in the pseudo enzymatic domain DI of human OAS3
OAS3 displayed a higher affinity for dsRNA in intact cells than either OAS1 (show OAS1 Antibodies) or OAS2 (show OAS2 Antibodies), consistent with its dominant role in RNase L (show RNASEL Antibodies) activation.
Preliminary study suggests that OAS (show SMOC1 Antibodies) gene cluster and CD209 (show CD209 Antibodies) gene polymorphisms influence the risk of developing clinical symptoms in Chikungunya virus-infected patients.
Common variation at 12q24.13 (OAS3 intron) influences chronic lymphocytic leukemia risk.
The combined high affinity for double-stranded RNA and the capability to produce 2'-5'-linked oligoadenylates of sufficient length to activate RNase L (show RNASEL Antibodies) suggests that OAS3 is a potent activator of RNase L (show RNASEL Antibodies).
The results suggest that OAS1 (show OAS1 Antibodies)-OAS3-OAS2 (show OAS2 Antibodies) haplotypes are associated with differential susceptibility to clinical outcomes of dengue infection.
among the members of the OAS (show SMOC1 Antibodies) family, OAS1 (show OAS1 Antibodies) p46 (show POLDIP3 Antibodies) and OAS3 p100 mediate the RNase L (show RNASEL Antibodies)-dependent antiviral activity against HCV
The data suggest a possible association between OAS2 (show OAS2 Antibodies) and OAS3 single nucleotide polymorphisms and the outcome of tick-borne encephalitis virus infection in a Russian population.
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.
2'-5' oligoadenylate synthetase 3
, 2'-5'-oligoadenylate synthase 3
, 2'-5'oligoadenylate synthetase 3
, (2-5')oligo(A) synthase 3
, (2-5')oligo(A) synthetase 3
, 2'-5'oligoadenylate synthetase p100
, 2-5A synthase 3
, 2-5A synthetase 3
, p100 OAS
, 2',5'-oligoadenylate synthetase-like 10
, 2'-5' oligoadenylate synthetase-like 10
, 2'-5'-oligoadenylate synthetase 3, 100kDa
, 2'-5'-oligoadenylate synthetase 3-like
, 2'-5'-oligoadenylate synthase 3-like
, 2'-5'-oligoadenylate synthetase 3