Browse our anti-Islet Amyloid Polypeptide (IAPP) Antibodies

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anti-Islet Amyloid Polypeptide Antibodies (IAPP)
On are 118 Islet Amyloid Polypeptide (IAPP) Antibodies from 22 different suppliers available. Additionally we are shipping Islet Amyloid Polypeptide Kits (78) and Islet Amyloid Polypeptide Proteins (7) and many more products for this protein. A total of 240 Islet Amyloid Polypeptide products are currently listed.
Amylin, DAP, IAP, LOC100230121

Most Popular Reactivities for anti-Islet Amyloid Polypeptide (IAPP) Antibodies

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All available anti-Islet Amyloid Polypeptide Antibodies

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Top referenced anti-Islet Amyloid Polypeptide Antibodies

  1. Human Monoclonal IAPP Primary Antibody for IHC (fro), IF - ABIN118954 : Gong, Liu, Zeng, Peng, Chen, Zhou, Li: Amylin deposition in the kidney of patients with diabetic nephropathy. in Kidney international 2007 (PubMed)
    Show all 7 references for 118954

  2. Human Monoclonal IAPP Primary Antibody for ICC, IHC (fro) - ABIN153560 : Nakamura, Okabayashi, Ageyama, Koie, Sankai, Ono, Fujimoto, Terao: Transthyretin amyloidosis and two other aging-related amyloidoses in an aged vervet monkey. in Veterinary pathology 2008 (PubMed)
    Show all 6 references for 153560

  3. Cat (Feline) Polyclonal IAPP Primary Antibody for IHC (fro), IHC (p) - ABIN115737 : Mulder, Ahrén, Stridsberg, Sundler: Non-parallelism of islet amyloid polypeptide (amylin) and insulin gene expression in rats islets following dexamethasone treatment. in Diabetologia 1995 (PubMed)
    Show all 2 references for 115737

  4. Dog (Canine) Polyclonal IAPP Primary Antibody for WB - ABIN610646 : Cifuentes-Diaz, Frugier, Tiziano, Lacène, Roblot, Joshi, Moreau, Melki: Deletion of murine SMN exon 7 directed to skeletal muscle leads to severe muscular dystrophy. in The Journal of cell biology 2001 (PubMed)
    Show all 2 references for 610646

More Antibodies against Islet Amyloid Polypeptide Interaction Partners

Human Islet Amyloid Polypeptide (IAPP) interaction partners

  1. Data suggest that single aromatic/hydrophobic amino acid residues within IAPP (islet amyloid polypeptide) amyloid core region are able to control its interaction with amyloid-beta(1-40) or amyloid-beta(1-42) but not IAPP self-assembly; four aromatic/hydrophobic residues are able to control both IAPP amyloid self-assembly and its cross-interaction with amyloid-beta(1-40) or amyloid-beta(1-42).

  2. Data show that aluminum (Al3+) could inhibit islet amyloid polypeptide hIAPP(11-28) fibrillogenesis.

  3. The absence of BACE2 (show BACE2 Antibodies) ameliorates glucose tolerance defects induced by IAPP overexpression in the beta-cell and promotes beta-cell survival.

  4. This study supports the elucidation of the structural basis of IAPP amyloid formation and highlights the extent of amyloid fibril polymorphism.

  5. Data suggest that a single GlcNAc residue at CTR (show CALCR Antibodies) N130 (asparagine 130) is responsible for enhanced affinity of calcitonin (show CALCA Antibodies) for CTR (show CALCR Antibodies) ECD (show SHFM1 Antibodies); the same appears to apply for enhanced affinity of amylin for RAMP2 (show RAMP2 Antibodies)-CTR (show CALCR Antibodies) ECD (show SHFM1 Antibodies). [GlcNAc = N-acetylglucosamine; CTR (show CALCR Antibodies) = calcitonin receptor (show CALCR Antibodies); ECD (show SHFM1 Antibodies) = extracellular domain; RAMP2 (show RAMP2 Antibodies) = receptor (calcitonin) activity modifying protein 2 (show RAMP2 Antibodies)].

  6. The kinetics of human amylin amyloid formation can be monitored by SYPRO-orange fluorescence and match the time course determined with thioflavin-T assays.

  7. effect of cholesterol on the amyloidogenicity of IAPP

  8. Chondroitin sulfate A has an intensive promotion effect on the fibrillation of human IAPP at the palmitoyloleoylphosphatidylcholine (POPC) membrane, which is larger than the total effect of Chondroitin sulfate A alone and POPC alone.

  9. C4BP (show C4BPA Antibodies) protects beta-cells from IAPP cytotoxicity by modulating IAPP fibril formation extracellularly and also, after uptake by the cells, by enhancing cholesterol synthesis.

  10. beta-hairpin peptide inhibitor of IAPP aggregation that are stabilized in that conformation, or even forced to remain in the hairpin conformation by a backbone cyclization constraint, display superior activity as inhibitors.

Pig (Porcine) Islet Amyloid Polypeptide (IAPP) interaction partners

Mouse (Murine) Islet Amyloid Polypeptide (IAPP) interaction partners

  1. These data suggest participation by both soluble and fibrillar aggregates in IAPP-induced islet inflammation. IAPP-induced activation of TLR2 (show TLR2 Antibodies) and secretion of IL-1 (show IL1A Antibodies) may be important therapeutic targets to prevent amyloid-associated beta cell dysfunction.

  2. Hypothalamic amylin is transcriptionally regulated by leptin (show LEP Antibodies), that it can act directly on ObRb (show LEPR Antibodies) neurons in concert with leptin (show LEP Antibodies), and that it regulates feeding.

  3. Matrix Metalloproteinase-9 (show MMP9 Antibodies) Protects Islets from Amyloid-induced Toxicity.

  4. Data indicate that T-cell receptors that react to chromogranin A (ChgA (show CHGA Antibodies)) and islet amyloid polypeptide precursor (IAPP) autoantigens were impaired when the thymic stromal cells lacked thymus-specific serine protease (TSSP (show PRSS16 Antibodies)).

  5. Study the physiologic actions of IAPP on pancreatic beta cells, which secrete this peptide together with insulin (show INS Antibodies) upon glucose stimulation. Explore the signaling pathways and mitogenic actions of IAPP on beta cells.

  6. deletion of the DeltaN isoforms of p63 (show CKAP4 Antibodies) or p73 (show ARHGAP24 Antibodies) leads to metabolic reprogramming and regression of p53 (show TP53 Antibodies)-deficient tumours through upregulation of IAPP, the gene that encodes amylin, a 37-amino-acid peptide co-secreted with insulin (show INS Antibodies) by the beta cells of the pancreas

  7. The stability, conformational dynamics and association force of different single-layer models of the full-length wild-type and glycine mutants of amylin, were investigated.

  8. studies have identified a novel TXNIP (show TXNIP Antibodies)/miR (show MLXIP Antibodies)-124a/FoxA2 (show FOXA2 Antibodies)/IAPP signaling cascade linking the critical beta-cell signaling pathways of TXNIP (show TXNIP Antibodies) and IAPP

  9. MMP-9 (show MMP9 Antibodies) constitutes an endogenous islet protease that limits islet amyloid deposition and its toxic effects via degradation of hIAPP.

  10. Data suggest that amylin and leptin (show LEP Antibodies) play additive roles in regulating energy homeostasis via activation of overlapping signalling pathways; mechanisms may be different in hypothalamus, muscle, and liver and in cases of endoplasmic reticulum stress.

Islet Amyloid Polypeptide (IAPP) Antigen Profile

Antigen Summary

Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.

Alternative names and synonyms associated with Islet Amyloid Polypeptide (IAPP)

  • islet amyloid polypeptide (LOC100230121) antibody
  • islet amyloid polypeptide (IAPP) antibody
  • islet amyloid polypeptide (Iapp) antibody
  • islet amyloid polypeptide-like (LOC100520838) antibody
  • Amylin antibody
  • DAP antibody
  • IAP antibody
  • LOC100230121 antibody

Protein level used designations for IAPP

islet amyloid polypeptide , Islet amyloid polypeptide (diabetes-associated peptide; amylin) , amylin , diabetes-associated peptide , insulinoma amyloid peptide , DAP , amyloid protein

100230121 Taeniopygia guttata
3375 Homo sapiens
751513 Felis catus
100381251 Sus scrofa
24476 Rattus norvegicus
100135550 Cavia porcellus
15874 Mus musculus
100009489 Oryctolagus cuniculus
403909 Canis lupus familiaris
100138011 Bos taurus
101120402 Ovis aries
396362 Gallus gallus
101832022 Mesocricetus auratus
100520838 Sus scrofa
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