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Data indicate that formation of a primarily alpha-helical C-terminal region of prolactin releasing peptide (PrRP) is critical for receptor activation.
PrRP has a likely role in pheochromocytomas, based on its high expression in tumor tissue
Review discusses the ancestral relationship between prolactin-releasing hormone and the C-terminal RF-motif amide precursor peptide (C-RF).
The medial amygdala-medullary PrRP-synthesizing neuron pathway plays an important role in neuroendocrine responses to contextual conditioned fear
These results suggest that p53 (show TP53 ELISA Kits) may regulate the differentiation of trophoblast giant cells, and may control the physiological PrRP stimuli in mouse placentas.
Data report that PrRP and its receptor, GPR10 (show PRLHR ELISA Kits), were found in the mouse substantia nigra pars (show EPRS ELISA Kits) compacta (SNpc), the main location of dopaminergic (DA) neurons of the nigrostriatal system.
Stimulates prolactin (PRL) release and regulates the expression of prolactin through its receptor GPR10. May stimulate lactotrophs directly to secrete PRL.
prolactin releasing hormone
, prolactin releasing peptide
, prolactin-releasing peptide
, preproprolactin-releasing peptide
, prolactin-releasing hormone