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Browse our Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) ELISA Kits

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Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit ELISA Kits (CACNA1C)
On www.antibodies-online.com are 4 Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) ELISA Kits from 3 different suppliers available. Additionally we are shipping Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Antibodies (189) and Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Proteins (10) and many more products for this protein. A total of 206 Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit products are currently listed.
Synonyms:
C-LTCC, ca(v)1.2, CACH2, CACH2C, CACN2, Cacna1c, CACNL1A1, CAV1.2, Cchl1a1, CHCACHA1C, ICA, isl, LQT8, MBC, MELC-CC, RATIVS302, TS
list all ELISA KIts Gene Name GeneID UniProt
Human CACNA1C CACNA1C 775 Q13936
CACNA1C 12288 Q01815
Rat CACNA1C CACNA1C 24239 P22002

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Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) ELISA Kits by Reactivity

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More ELISA Kits for Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit Interaction Partners

Xenopus laevis Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. Competitive and non-competitive regulation of calcium-dependent inactivation in CaV1.2 L-type Ca2 (show CA2 ELISA Kits)+ channels by calmodulin and Ca2 (show CA2 ELISA Kits)+-binding protein 1.

Rabbit Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. a direct physical interaction between the N terminus (NT) and C terminus (CT) of the main subunit of the L-type Ca(2 (show CA2 ELISA Kits)+) channel CaV1.2, alpha1C, is reported.

  2. These results reveal a new dimension of regulation of Ca(V)1.2 channels through phosphorylation of the Hook domains of their beta subunits.

  3. These findings suggest that N-glycosylation contributes to the surface expression and voltage-dependent gating of Cav1.2.

  4. Data show that cardiac L-type calcium (CaV1.2) channels form clusters that undergo dynamic, reciprocal, allosteric interactions.

  5. these findings provide evidence for a new role of Homer1 (show HOMER1 ELISA Kits) supporting the regulation of Cav1.2 channels by STIM1 (show STIM1 ELISA Kits).

  6. structural flexibility of CaV1.2 and CaV2.2 (show CACNA1B ELISA Kits) I-II proximal linker

  7. These results suggest a complex antagonistic interplay between G(q)-activated PKC and Gbetagamma in regulation of L-VDCC, in which multiple cytosolic segments of alpha(1C) are involved.

  8. There were substantial transmural gradients in Cav1.2, KChIP2 (show KCNIP2 ELISA Kits), ERG (show KCNH2 ELISA Kits), KvLQT1 (show KCNQ1 ELISA Kits), Kir2.1 (show KCNJ2 ELISA Kits), NCX1 (show SLC8A1 ELISA Kits), SERCA2a (show ATP2A2 ELISA Kits) and RyR2 (show RYR2 ELISA Kits) at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

  9. Ca v1.2 binding site for PP2A and PP2B (show CAN ELISA Kits)

  10. Swapping the I-II intracellular linker between L-type CaV1.2 and R-type CaV2.3 (show CACNA1E ELISA Kits) high-voltage gated calcium channels exchanges activation attributes.

Human Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. Authors assessed the effect across the human brain of the CACNA1C rs1006737 genotype on FA, in a Caucasian clinical sample as well as in health, and whether this genotype effect was different between diagnostic groups and whether it interacted with the ZNF804A rs1344706 genotype.

  2. The study supports the association of SNP rs1006737 with bipolar disorder-I (BD-I) and suggests that CACNA1C SNP rs1006737 and Bcl-2 SNP rs956572, or specific causal variants in linkage disequilibrium with these proxies, act independently to increase risk and Intracellular Ca(2+) dyshomeostasis (ICDH) in BD-I.

  3. The Ca channel alpha 1C (CACNA1C) mRNA and protein expressions were noticeably elevated in H-Cd group. These findings suggest that CACNA1C might be implicated in Cd transport in human placenta.

  4. Rare CACNA1C genetic variants may contribute to the underlying pathogenic basis for some cases of sudden explaned dealth in the young in either a gain or loss-of-function mechanism.

  5. Authors validated CACNA1C to be the direct target gene of miR (show MLXIP ELISA Kits)-29a-3p, and also established the negative regulatory relationship between miR (show MLXIP ELISA Kits)-29a-3p and CACNA1C via studying the relative luciferase activity.

  6. No significant associations (regardless of correction for multiple testing) between the BDNF (show BDNF ELISA Kits) and CACNA1C risk variants and cognitive functioning were found in either patients or controls.

  7. the association of rs1006737 with gray matter volume in a sample of 278 healthy Han Chinese, was examined.

  8. the function of purified human Cav1.2 in proteoliposomes, was investigated.

  9. The linking variation in the CACNA1C gene is a neurochemical marker of neuroaxonal plasticity in those with bipolar disorder.

  10. Copy number increase of CACNA1C are associated with esophageal squamous cell carcinoma.

Mouse (Murine) Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. The authors show that phosphorylation of S1928 displaces the beta-2 adrenergic receptor (show ADRB2 ELISA Kits) from Cav1.2 upon beta-adrenergic stimulation rendering Cav1.2 refractory for several minutes from further beta-adrenergic stimulation.

  2. findings suggest that Hap1 (show HAP1 ELISA Kits) is important for insulin (show INS ELISA Kits) secretion of pancreatic beta-cells via regulating the intracellular trafficking and plasma membrane localization of Cav1.2, providing new insight into the mechanisms that regulate insulin (show INS ELISA Kits) release from pancreatic beta-cells.

  3. these data indicate for the first time a functional interaction between Orai1 (show TMEM132A ELISA Kits), TRPC1 (show TRPC1 ELISA Kits), and CaV1.2 channels in Vascular Smooth Muscle Cells, confirming that upon agonist stimulation, vessel contraction involves Ca(2 (show CA2 ELISA Kits)+) entry due to co-activation of Orai1 (show TMEM132A ELISA Kits)- and TRPC1 (show TRPC1 ELISA Kits)-dependent store-operated Ca(2 (show CA2 ELISA Kits)+) channels and L-type Ca(2 (show CA2 ELISA Kits)+) channels.

  4. These findings suggest that Trpc3 (show TRPC3 ELISA Kits) is a mediator of pathologic cardiac hypertrophy not only through mediating part of the Ca(2 (show CA2 ELISA Kits)+) influx, but also through control of CaV1.2 expressions.

  5. K(ATP) channel gain-of-function leads to increased myocardial L-type Ca(2 (show CA2 ELISA Kits)+) current and contractility in Cantu (show ABCC9 ELISA Kits) syndrome.

  6. This study demonstrate a role of Cav1.2 in regulating survival of young hippocampal neurons in living mice by studying both forebrain-Cav1.2 cKO mice.

  7. Results provide evidence that decreased Cacna1c expression has a protective role in the modulation of age-related cognitive declines, and support an interaction between Cacna1c, sex and memory impairment

  8. Both the extracellular PFXYD motif and the transmembrane domain of PLM (show FXYD1 ELISA Kits) but not the cytoplasmic tail were necessary for regulation of peak L-type Ca(2 (show CA2 ELISA Kits)+) current amplitude.

  9. Treatment of MSC (show MSC ELISA Kits) with BMP4 (show BMP4 ELISA Kits) caused a significant increase in expression of Cav1.2, a delay in expression of Cav1.1 (show CACNA1S ELISA Kits), and a reduction in the duration of calcium transients when extracellular calcium was removed

  10. data suggest that miR (show MLXIP ELISA Kits)-103 inhibits osteoblast proliferation mainly through suppression of Cav1.2 expression under simulated microgravity condition

Cow (Bovine) Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. These results suggest that structural rearrangements of CaV1.2 generated through the binding of BayK8644 or FPL64176, by altering the channel activity, could affect depolarization-evoked catecholamine secretion prior to cation transport.

  2. CaV3.1 (show CACNA1G ELISA Kits) structural analysis and comparison to CaV1.2 channel

Guinea Pig Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) interaction partners

  1. findings suggested that the expressions of the cardiac CACNA1C were under the CLOCK-BMAL1 (show ARNTL ELISA Kits) regulation, probably through the PI3K-Akt (show AKT1 ELISA Kits) signal pathway

  2. These results suggest that PKA and phosphatase(s) attached on or near the Ca(V)1.2 channel regulate the basal channel activity, presumably through modulation of the dynamic CaM (show CALM ELISA Kits) interaction with the channel.

  3. CaM (show CALM ELISA Kits) may tether to the channel with its single lobe, leading to multiple CaM (show CALM ELISA Kits) molecule binding to increase the grade of Ca(2 (show CA2 ELISA Kits)+)-dependent regulation of Cav1.2

Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C) Antigen Profile

Antigen Summary

This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits.

Alternative names and synonyms associated with Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C)

  • calcium channel, voltage-dependent, L type, alpha 1C subunit (cacna1c) Elisa Kit
  • calcium channel, voltage-dependent, L type, alpha 1C subunit (CACNA1C) Elisa Kit
  • calcium channel (CACB) Elisa Kit
  • calcium channel, voltage-dependent, L type, alpha 1C subunit (Cacna1c) Elisa Kit
  • cardiac L-type calcium channel (CACH2C) Elisa Kit
  • Red blood cell count (RBC) Elisa Kit
  • C-LTCC Elisa Kit
  • ca(v)1.2 Elisa Kit
  • CACH2 Elisa Kit
  • CACH2C Elisa Kit
  • CACN2 Elisa Kit
  • Cacna1c Elisa Kit
  • CACNL1A1 Elisa Kit
  • CAV1.2 Elisa Kit
  • Cchl1a1 Elisa Kit
  • CHCACHA1C Elisa Kit
  • ICA Elisa Kit
  • isl Elisa Kit
  • LQT8 Elisa Kit
  • MBC Elisa Kit
  • MELC-CC Elisa Kit
  • RATIVS302 Elisa Kit
  • TS Elisa Kit

Protein level used designations for CACNA1C

ZfCav1.2 , island beat , voltage-dependent L-type calcium channel subunit alpha-1C , L-type Ca channel alpha 1 subunit , L-type calcium channel CaV1.2 , atrium L-type calcium channel , calcium channel, voltage-dependent, L type, alpha 1C subunit , voltage-dependent L-type calcium channel subunit alpha-1C-like , calcium channel voltage-dependent L type Cav1.2, alpha 1c subunit , CaCB receptor , smooth muscle calcium channel blocker , DHPR, alpha-1 subunit , calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle , calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit , voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10* , L-type Cav1.2 , brain class C , calcium channel voltage-dependent alpha1c subunit , neuronal voltage-gated calcium channel alpha 1C subunit , skeletal muscle-specific calcium channel , voltage-gated calcium channel subunit alpha Cav1.2 , L-type calcium channel alpha-1 subunit , RBC , calcium channel, voltage-dependent, alpha 1C subunit , voltage-gated calcium channel alpha 1C subunit , L-type voltage-gated calcium channel alpha1C subunit ChCaChA1C , L-type voltage-dependent calcium channel alpha-1 subunit , cardiac L-type calcium channel , Voltage-dependent L-type calcium channel subunit alpha-1C

GENE ID SPECIES
170581 Danio rerio
403516 Canis lupus familiaris
100442085 Pongo abelii
100462911 Xenopus laevis
100101555 Oryctolagus cuniculus
775 Homo sapiens
12288 Mus musculus
24239 Rattus norvegicus
408015 Bos taurus
395891 Gallus gallus
100135490 Cavia porcellus
100144322 Oryctolagus cuniculus
101180626 Sus scrofa
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