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Browse our anti-G Protein-Coupled Receptor 119 (GPR119) Antibodies

Full name:
anti-G Protein-Coupled Receptor 119 Antibodies (GPR119)
On www.antibodies-online.com are 83 G Protein-Coupled Receptor 119 (GPR119) Antibodies from 15 different suppliers available. Additionally we are shipping G Protein-Coupled Receptor 119 Proteins (4) and many more products for this protein. A total of 93 G Protein-Coupled Receptor 119 products are currently listed.
Synonyms:
GPCR2, GPR119
list all antibodies Gene Name GeneID UniProt
GPR119 139760 Q8TDV5
GPR119 302813 Q7TQN8
GPR119 236781 Q7TQP3

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Most Popular Reactivities for anti-G Protein-Coupled Receptor 119 (GPR119) Antibodies

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anti-Human G Protein-Coupled Receptor 119 Antibodies:

anti-Rat (Rattus) G Protein-Coupled Receptor 119 Antibodies:

anti-Mouse (Murine) G Protein-Coupled Receptor 119 Antibodies:

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Top referenced anti-G Protein-Coupled Receptor 119 Antibodies

  1. Mouse (Murine) Polyclonal G Protein-Coupled Receptor 119 Primary Antibody for EIA, IHC (fro) - ABIN1107422 : Sakamoto, Inoue, Kawakami, Miyawaki, Miyamoto, Mizuta, Itakura: Expression and distribution of Gpr119 in the pancreatic islets of mice and rats: predominant localization in pancreatic polypeptide-secreting PP-cells. in Biochemical and biophysical research communications 2006 (PubMed)

  2. Human Polyclonal G Protein-Coupled Receptor 119 Primary Antibody for IF, ELISA - ABIN1535625 : Ross, Grafham, Coffey, Scherer, McLay, Muzny, Platzer, Howell, Burrows, Bird, Frankish, Lovell, Howe, Ashurst, Fulton, Sudbrak, Wen, Jones, Hurles, Andrews, Scott, Searle, Ramser, Whittaker, Deadman et al.: The DNA sequence of the human X chromosome. ... in Nature 2005 (PubMed)

  3. Human Polyclonal G Protein-Coupled Receptor 119 Primary Antibody for EIA, WB - ABIN374997 : Overton, Fyfe, Reynet: GPR119, a novel G protein-coupled receptor target for the treatment of type 2 diabetes and obesity. in British journal of pharmacology 2008 (PubMed)

More Antibodies against G Protein-Coupled Receptor 119 Interaction Partners

Human G Protein-Coupled Receptor 119 (GPR119) interaction partners

  1. Describe novel small-molecule GPR119 agonists with high receptor selectivity and capacity to induce glucose-stimulated insulin (show INS Antibodies) secretion.

  2. The GPR119 agonist, HD0471042 increased intracellular cAMP levels in stably human GPR119 expressing CHO cells.

  3. Oxidized-LDL significantly induces lincRNA-DYNLRB2 (show DYNLRB2 Antibodies)-2 expression, which promotes ABCA1 (show ABCA1 Antibodies)-mediated cholesterol efflux and inhibits inflammation through GPR119 in THP-1 (show GLI2 Antibodies) cells.

  4. Replacement of the three methyl groups in 1 with metabolically stable moieties led to the identification of compound 34, a potent and efficacious GPR119 agonist with improved pharmacokinetic (PK) properties.

  5. transfection of GLUTag cells with recombinant human GPR119 results in a constitutive and apparently ligand-independent increase of proglucagon (show GCG Antibodies) gene promoter activity and proglucagon (show GCG Antibodies) mRNA content.

  6. Results provide evidence of an islet-gastrointestinal distribution of GPR119, its expression in pancreatic beta and alpha cells, and its possible involvement in islet function.

  7. Data suggest that GPR119 activation/up-regulation in skeletal muscle impairs fatty acid and glucose oxidation; diet-induced obesity appears to up-regulate skeletal muscle GPR119.

  8. Data show that Phe-V:13 can serve as an aromatic lock for the proposed active conformation of the Trp (show TBPL1 Antibodies)-VI:13 rotameric switch, being involved in the global movement of TM-V and TM-VI in 7TM receptor (show CHRM2 Antibodies) activation.

  9. findings show that N-oleoyldopamine (OLDA)& structurally related hydroxybenzyl amides are robust activators of GPR119; studies indicate that multiple, distinct classes of lipid amides, acting via GPR119, may be important modulators of glucose homeostasis

  10. GPR119 therefore represents a novel and attractive potential target for the therapy of obesity and related metabolic disorders.

Mouse (Murine) G Protein-Coupled Receptor 119 (GPR119) interaction partners

  1. fat-derived monoacylglycerols are potent candidates for mediating fat-induced GLP-1 (show GCG Antibodies) release through GPR119 in vivo.

  2. GPR119 in L-cells plays a key role in oral lipid-triggered GLP-1 (show GCG Antibodies) secretion.

  3. Data indicate that G-protein coupled receptor 119 (GPR119) knockout prevents the therapeutic effects of Gordonoside F.

  4. Describe novel small-molecule GPR119 agonists with high receptor selectivity and capacity to induce glucose-stimulated insulin (show INS Antibodies) secretion.

  5. Novel GPR119 agonist, HD0471042, effectively controlled glucose levels and prevented weight gain in type 2 diabetic mice.

  6. AR231453, a GPR119 agonist, can stimulate beta-cell replication and improve islet graft function

  7. Our results demonstrate that combining a GPR119 agonist with a DPP-IV (show DPP4 Antibodies) inhibitor may offer a novel therapeutic strategy for stimulating beta-cell regeneration and reversing diabetes.

  8. Data suggest that GPR119 activation/up-regulation in skeletal muscle impairs fatty acid and glucose oxidation; diet-induced obesity appears to up-regulate skeletal muscle GPR119.

  9. Data suggest that, in lean mice, 2-oleoylglycerol and linoleylethanolamine serve as physiologically relevant endogenous GPR119 agonists that mediate receptor activation upon nutrient uptake.

  10. GPR119 engages multiple complementary pathways for control of glucose homeostasis.

G Protein-Coupled Receptor 119 (GPR119) Antigen Profile

Antigen Summary

This gene encodes a member of the rhodopsin subfamily of G-protein-coupled receptors that is expressed in the pancreas and gastrointestinal tract. The encoded protein is activated by lipid amides including lysophosphatidylcholine and oleoylethanolamide and may be involved in glucose homeostasis. This protein is a potential drug target in the treatment of type 2 diabetes.

Alternative names and synonyms associated with G Protein-Coupled Receptor 119 (GPR119)

  • G protein-coupled receptor 119 (GPR119) antibody
  • G protein-coupled receptor 119 (LOC100348687) antibody
  • G protein-coupled receptor 119 (Gpr119) antibody
  • G-protein coupled receptor 119 (Gpr119) antibody
  • GPCR2 antibody
  • GPR119 antibody

Protein level used designations for GPR119

G protein-coupled receptor 119 , G-protein coupled receptor 2 , glucose-dependent insulinotropic receptor , G-protein coupled receptor 119

GENE ID SPECIES
428690 Gallus gallus
446009 Takifugu rubripes
465858 Pan troglodytes
492134 Canis lupus familiaris
524232 Bos taurus
703368 Macaca mulatta
100348687 Oryctolagus cuniculus
139760 Homo sapiens
302813 Rattus norvegicus
236781 Mus musculus
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