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Browse our anti-TRPV4 (TRPV4) Antibodies

Full name:
anti-Transient Receptor Potential Cation Channel, Subfamily V, Member 4 Antibodies (TRPV4)
On www.antibodies-online.com are 101 Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) Antibodies from 18 different suppliers available. Additionally we are shipping TRPV4 Proteins (6) and TRPV4 Kits (2) and many more products for this protein. A total of 123 TRPV4 products are currently listed.
Synonyms:
0610033B08Rik, CMT2C, HMSN2C, Otrpc4, SMAL, SPSMA, SSQTL1, Trp12, VR-OAC, VRL-2, VRL2, Vroac, wu:fp52e02
list all antibodies Gene Name GeneID UniProt
TRPV4 59341 Q9HBA0
TRPV4 63873 Q9EPK8
TRPV4 66026 Q9ERZ8

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anti-Human TRPV4 Antibodies:

anti-Mouse (Murine) TRPV4 Antibodies:

anti-Rat (Rattus) TRPV4 Antibodies:

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Top referenced anti-TRPV4 Antibodies

  1. Mouse (Murine) Polyclonal TRPV4 Primary Antibody for IHC, WB - ABIN351282 : Arniges, Fernuandez-Fernuandez, Albrecht, Schaefer, Valverde: Human TRPV4 channel splice variants revealed a key role of ankyrin domains in multimerization and trafficking. in The Journal of biological chemistry 2006 (PubMed)
    Show all 6 references for ABIN351282

  2. Human Polyclonal TRPV4 Primary Antibody for ICC, IF - ABIN259364 : Butenko, Dzamba, Benesova, Honsa, Benfenati, Rusnakova, Ferroni, Anderova: The increased activity of TRPV4 channel in the astrocytes of the adult rat hippocampus after cerebral hypoxia/ischemia. in PLoS ONE 2012 (PubMed)
    Show all 4 references for ABIN259364

  3. Cow (Bovine) Polyclonal TRPV4 Primary Antibody for IHC, WB - ABIN2776284 : Sampat, Dermksian, Oungoulian, Winchester, Bulinski, Ateshian, Hung: Applied osmotic loading for promoting development of engineered cartilage. in Journal of biomechanics 2013 (PubMed)

More Antibodies against TRPV4 Interaction Partners

Zebrafish Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) interaction partners

  1. TRPP2 and TRPV4 are mechanosensitive channels in the endocardium.Oscillatory flow modulates mechanosensitive klf2a expression through trpv4 and trpp2 during heart valve development.

  2. TRPP2 utilizes TRPV4 to form a mechano- and thermosensitive molecular sensor in the cilium.

  3. Age-dependence of heat-activated seizure susceptibility mimicks the mRNA expression of TRPV4 and glutamate (show GRIN2A Antibodies) receptors.

  4. TRPV4 present in all sensory organs of adult zebrafish.

  5. Study reports cloning of a zebrafish trpv4 cDNA and assaying its expression during embryogenesis; trpv4 is expressed as maternal mRNA in 4-cell embryos and later zygotic expression is first observed in the forming notochord at the one somite stage.

  6. OS-9 (show OS9 Antibodies) regulates the secretory transport of TRPV4 and appears to protect TRPV4 subunits from the precocious ubiquitination and ER-associated degradation.

Human Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) interaction partners

  1. both TRPV2 (show TRPV2 Antibodies) and TRPV4 are involved in migration of human cardiac c-kit (show KIT Antibodies)(+) progenitor cells.

  2. Data show that arylalkymine N-acetyltransferase (AANAT (show AANAT Antibodies)) levels and melatonin synthesis change after transient receptor potential channel 4 (show TRPC4 Antibodies) (TRPV4 channel) stimulation in ciliary body epithelial cells .

  3. TRPV4-induced calcium mobilization and inflammatory responses were enhanced in cystic fibrosis transmembrane conductance regulator (show CFTR Antibodies)-deficient cellular models.

  4. direct electrophysiological and pharmacological evidence for both TRPV4 and L-type Ca2 (show CA2 Antibodies)+ conductances, as well as a tetraethylammonium (TEA)- and paxilline-sensitive K+ conductance in human pulmonary fibroblasts.

  5. We demonstrate that pharmacological activation or inhibition of TRPV4 regulates Ca(2 (show CA2 Antibodies)+)-wave propagation from head to tail. Such findings may have wide application in male fertility-infertility, contraception and conservation of endangered species as well.

  6. These results confirm the function of TRPV4 in human cultured adipocytes and its regulation by insulin (show INS Antibodies).

  7. Helicobacter pylori infection-dependent DNA methylation (show HELLS Antibodies) suppressed TRPV4 expression in human gastric epithelia, suggesting that TRPV4 methylation may be involved in Helicobacter pylori-associated dyspepsia.

  8. Phorbol myristate acetate increased TRPV4 expression in U937 and THP-1 cells. (show PPARG Antibodies) There was no significant difference in TRPV4 expression in the nLDL group but a significant reduction in TRPV4 expression was detected in the oxLDL group.

  9. TRPV4 rs6606743 SNP was found to significantly contribute to the development of osmotic airway hyperresponsiveness in response to the decrease in osmolarity under inspiration of distilled water aerosol was studies in 189 patients with uncontrolled bronchial asthma, prevalence of AG + GG genotype frequency in the group of patients with asthma with osmotic hyperresponsiveness

  10. Report of an Italian family with scapuloperoneal spinal muscular atrophy harboring the heterozygous missense mutation c.806G>A in the TRPV4 gene (p. R269H) and a literature review about scapuloperoneal spinal muscular atrophy

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) interaction partners

  1. TRPV4 channels are important for bladder afferent signaling. TRPV4 -/- mice bladders generate more noxious sensory output, which is predominantly mediated through TRPV1 (show TRPV1 Antibodies) expressing high threshold nerve fibers.

  2. TRPV4 does not play a major role in the kidney or is efficiently compensated when deleted. TRPV4 is critical for the release of vasopressin (show AVP Antibodies), the sensation of thirst, and the central osmoregulation.

  3. These results suggest that the Na(+) signal generated in Nax (show SCN7A Antibodies)-positive glial cells leads to the activation of TRPV4-positive neurons in sCVOs to stimulate water intake by using EETs as gliotransmitters.

  4. TRPV4 plays a critical role in the transduction of mechanical forces and gets activated by cell swelling and surface expansion.

  5. The absence of TRPV4-ATP-mediated effects on C-fibers indicates a distinct neurobiology for this ion channel and implicates TRPV4 as a novel therapeutic target for neuronal hyperresponsiveness in the airways and symptoms, such as cough.

  6. Here we analyzed sperm motility function of Trpv4 knockout (KO) mouse in temperature-gradient conditions to elucidate the thermotaxis of mouse sperm and the involvement of TRPV4 in thermotaxis. Large numbers of wild-type (WT) mouse sperm migrated into the high level of the temperature gradient, and thermotaxis was confirmed. The ratio of migrated sperm at the high temperature level was decreased in the KO sperm.

  7. TRPV4 is expressed in mouse and rat gastric epithelium and contributes to ATP release and gastric emptying.

  8. TRPV4 protein was expressed after RAW 264.7 cells were treated with PPARgamma (show PPARG Antibodies) inhibitor T0070907 or preincubated with T0070709 before incubation with oxLDL for 24 h.T0070907 enhanced the basal expression of TRPV4 and protected RAW264.7 cells from oxLDL-induced TRPV4 down-regulation.

  9. TRPV4 channel activity modulates uterine contractility and might represent a therapeutic target to address preterm labor.

  10. TRPV4-AQP4 (show AQP4 Antibodies) interactions 'turbocharge' astroglial sensitivity to small osmotic gradients

Pig (Porcine) Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) interaction partners

  1. Data indicate a physiologic function of transient receptor potential vanilloid 4 (TRPV4) in the regulation of blood-cerebrospinal fluid barrier (BCSFB) permeability.

  2. Hyposmotic shock-induced TRPV4 channel activation regulates hemichannel-mediated ATP release and Na-K-ATPase (show ATP1A1 Antibodies) activity in lens epithelium.

  3. The large amounts of transported calcium and the short signaling ways suggest a potentially important role of TRPV4 in many physiological processes.

  4. TRPV4 is present in articular chondrocytes in swine, and chondrocyte response to hypo-osmotic stress is mediated by this channel, which involves both an extracellular Ca(2 (show CA2 Antibodies)+) and intracellular Ca(2 (show CA2 Antibodies)+) release.

Cow (Bovine) Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4) interaction partners

  1. TRPV4 channels activity in bovine articular chondrocytes are regulated by obesity-associated mediators.

  2. TRPV4 channels mediate cyclic strain-induced endothelial cell reorientation through integrin-to-integrin signaling.

TRPV4 Antigen Profile

Antigen Summary

This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with TRPV4

  • transient receptor potential cation channel, subfamily V, member 4 (trpv4) antibody
  • transient receptor potential cation channel, subfamily V, member 4 (TRPV4) antibody
  • transient receptor potential cation channel, subfamily V, member 4 (LOC100220808) antibody
  • transient receptor potential cation channel, subfamily V, member 4 (Trpv4) antibody
  • 0610033B08Rik antibody
  • CMT2C antibody
  • HMSN2C antibody
  • Otrpc4 antibody
  • SMAL antibody
  • SPSMA antibody
  • SSQTL1 antibody
  • Trp12 antibody
  • VR-OAC antibody
  • VRL-2 antibody
  • VRL2 antibody
  • Vroac antibody
  • wu:fp52e02 antibody

Protein level used designations for TRPV4

transient receptor potential cation channel subfamily V member 4 , transient receptor potential cation channel, subfamily V, member 4 , transient receptor potential cation channel subfamily V member 4-like , OSM9-like transient receptor potential channel 4 , osm-9-like TRP channel 4 , osmosensitive transient receptor potential channel 4 , transient receptor potential protein 12 , vanilloid receptor-like channel 2 , vanilloid receptor-related osmotically activated channel , vanilloid receptor-like protein 2 , vanilloid receptor-related osmotically-activated channel , VR-OAC , transient receptor potential cation channel, subfamily 5, member 4 , vanilloid receptor-related osmotically activated channel (Vroac) , vanilloid receptor-related osmotically activated channel protein

GENE ID SPECIES
557850 Danio rerio
709605 Macaca mulatta
100458589 Pongo abelii
100472561 Ailuropoda melanoleuca
100539676 Meleagris gallopavo
100590720 Nomascus leucogenys
100220808 Taeniopygia guttata
59341 Homo sapiens
63873 Mus musculus
66026 Rattus norvegicus
395427 Gallus gallus
486308 Canis lupus familiaris
100126845 Sus scrofa
540259 Bos taurus
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