You are viewing an incomplete version of our website. Please click to reload the website as full version.

Browse our Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) ELISA Kits

Full name:
Methyl CpG Binding Protein 2 (Rett Syndrome) ELISA Kits (MECP2)
On www.antibodies-online.com are 0 Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) ELISA Kits from different suppliers available. A total of 0 Methyl CpG Binding Protein 2 (Rett Syndrome) products are currently listed.
Synonyms:
1500041B07Rik, AUTSX3, BB130002, D630021H01Rik, Mbd5, MRX16, MRX79, MRXS13, MRXSL, PPMX, RS, RTS, RTT, WBP10, wu:fk96a04, zgc:111857
list all ELISA KIts Gene Name GeneID UniProt
Mouse MECP2 MECP2 17257 Q9Z2D6
Rat MECP2 MECP2 29386 Q00566
Human MECP2 MECP2 4204 P51608

Show all synonyms

More ELISA Kits for Methyl CpG Binding Protein 2 (Rett Syndrome) Interaction Partners

Zebrafish Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) interaction partners

  1. A mecp2-null allele mutation zebrafish model is developed and the animals are viable and fertile.

Mouse (Murine) Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) interaction partners

  1. Results confirm and extend earlier published findings that specific aspects of cholesterol metabolism in the CNS, particularly the biosynthetic pathway, are disrupted in mouse models with loss-of-function mutations in Mecp2

  2. Repression of TSC1 (show TSC1 ELISA Kits)/TSC2 (show TSC2 ELISA Kits) mediated by MeCP2 regulates human embryo lung fibroblast cell differentiation and proliferation.

  3. Data suggest that newborn Mecp2 null cortical neurons display critical transcriptional defects that lead to reduced neuronal responsiveness, which, in turn, delays and disrupts proper neuronal maturation

  4. absence leads to decreased cortical levels of the GAT-1 GABA transporter, facilitating cortical network hyper-excitability by increasing the activity of cortical GABAB receptors

  5. Knockdown of methyl-CpG-binding protein leads to upregulation of microRNA-137, which in turn represses expression of PTEN protein.

  6. Study demonstrates that the time course of N-methyl-D-aspartate receptor (show GRIN1 ELISA Kits) maturation is cell-type specific, and a new cell-type specific role for Mecp2 in the development of -methyl-D-aspartate receptor subunit composition.

  7. Data highlight functional hypoconnectivity in the medial prefrontal cortex as a potential substrate for behavioral disruption in Rett syndrome and other disorders associated with reduced expression of Mecp2 in frontal cortical regions.

  8. These findings indicate that tongue heat sensitivity and hypersensitivity are dependent on the expression of transient receptor potential vanilloid 1 which is regulated via MeCP2 signaling in trigeminal ganglion neurons innervating the tongue.

  9. We treated MeCP2-null mice from postnatal-day 28 for two weeks with desipramine, already tested in Rett syndrome , or mirtazapine, an antidepressant with limited side-effects, known to promote GABA release

  10. these results suggested that MeCP2 facilitated Tet3 (show TET3 ELISA Kits) activity, enhanced expression of pluripotency-related genes, and eventually improved the development of NT embryos.

Human Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) interaction partners

  1. we could not find any significant correlation between specific MECP2 mutations and individual clinical features or global clinical score in Rett syndrome patients

  2. findings demonstrate clear phenotype differences between FOXG1 (show FOXG1 ELISA Kits) and MECP2 disorders.

  3. Binding cooperativity makes MeCP2 an effective competitor with histone H1 (show H1F0 ELISA Kits) for accessible DNA sites. The relationship between MeCP2 binding specificity and cooperativity is discussed in the context of chromatin binding, neuronal function, and neuronal development.

  4. Our data indicate that these motifs are secondary contributors to DNA binding by MeCP2, and this view is supported by the absence of disease-causing missense mutations at these sites

  5. Six patients (5 females and 1 male) with intellectual disability and present with some Rett syndrome features showed missense methyl-CpG binding protein 2 (MECP2) variants.

  6. Repression of TSC1 (show TSC1 ELISA Kits)/TSC2 (show TSC2 ELISA Kits) mediated by MeCP2 regulates human embryo lung fibroblast cell differentiation and proliferation.

  7. This study demonstrated that the MECP2 duplication of Autism showed that spine pathology in brain.

  8. Our findings confirm a high mutation frequency in classic RTT (92%) and a correlation between the MECP2 mutation type and clinical severity. We also demonstrate limitations of XCI in explaining all of the phenotypic differences in RTT.

  9. Data show that MeCP2 promotes gastric cancer (GC) cell proliferation via FOXF1 (show FOXF1 ELISA Kits)-mediated Wnt5a (show WNT5A ELISA Kits)/beta-Catenin (show CTNNB1 ELISA Kits) signaling pathway, and suppresses GC cell apoptosis through MYOD1 (show MYOD1 ELISA Kits)-mediated Caspase-3 (show CASP3 ELISA Kits) signaling pathway.

  10. To our knowledge, we describe the first association between MECP2 mutation, chromosomal abnormalities and high sister-chromatid exchange frequency

Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2) Antigen Profile

Antigen Summary

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.

Alternative names and synonyms associated with Methyl CpG Binding Protein 2 (Rett Syndrome) (MECP2)

  • methyl CpG binding protein 2 (mecp2) Elisa Kit
  • methyl CpG binding protein 2 (Mecp2) Elisa Kit
  • methyl CpG binding protein 2 (Rett syndrome) (MECP2) Elisa Kit
  • methyl CpG binding protein 2 (Rett syndrome) (mecp2) Elisa Kit
  • 1500041B07Rik Elisa Kit
  • AUTSX3 Elisa Kit
  • BB130002 Elisa Kit
  • D630021H01Rik Elisa Kit
  • Mbd5 Elisa Kit
  • MRX16 Elisa Kit
  • MRX79 Elisa Kit
  • MRXS13 Elisa Kit
  • MRXSL Elisa Kit
  • PPMX Elisa Kit
  • RS Elisa Kit
  • RTS Elisa Kit
  • RTT Elisa Kit
  • WBP10 Elisa Kit
  • wu:fk96a04 Elisa Kit
  • zgc:111857 Elisa Kit

Protein level used designations for MECP2

methyl-CpG-binding protein 2 , meCp-2 protein , meCP-2 protein , methyl-CpG-binding protein MeCP2

GENE ID SPECIES
335250 Danio rerio
17257 Mus musculus
29386 Rattus norvegicus
4204 Homo sapiens
612973 Canis lupus familiaris
100328751 Oryctolagus cuniculus
398087 Xenopus laevis
539629 Bos taurus
Did you look for something else?