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Myotubularin Related Protein 14 ELISA Kits (MTMR14)
On www.antibodies-online.com are 2 Myotubularin Related Protein 14 (MTMR14) ELISA Kits from 1 different suppliers available. Additionally we are shipping Myotubularin Related Protein 14 Antibodies (67) and Myotubularin Related Protein 14 Proteins (6) and many more products for this protein. A total of 80 Myotubularin Related Protein 14 products are currently listed.
Synonyms:
1110061O04Rik, AW553738, C3orf29, C76151, fc14d11, jumpy, MGC131146, RGD1304842, wu:fc14d11
list all ELISA KIts Gene Name GeneID UniProt
MTMR14 64419 Q8NCE2
MTMR14 97287 Q8VEL2
Rat MTMR14 MTMR14 312634  

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Zebrafish Myotubularin Related Protein 14 (MTMR14) interaction partners

  1. Morpholino-mediated knockdown of MTMR14 results in morphologic abnormalities, a developmental motor phenotype characterized by diminished spontaneous contractions and abnormal escape response, and impaired excitation-contraction coupling.

Human Myotubularin Related Protein 14 (MTMR14) interaction partners

  1. This study provides the first in vivo evidence for a role of myotubularins, and in particular MTMR14, in the regulation of autophagy.

  2. The authors uncovered a key negative regulatory role in autophagy of a phosphatidylinositol 3-phosphate (PI3P) phosphatase Jumpy (MTMR14).

  3. C3orf29 encodes hJUMPY, a phosphoinositide 3-phosphate phosphatase that acts on PtdIns3P and PtdIns(3,5)P2. A missense mutation disrupts the catalytic activity in a patient with centronuclear myopathy.

Mouse (Murine) Myotubularin Related Protein 14 (MTMR14) interaction partners

  1. Data (including data from studies in knockout mice) suggest that Mtmr14 plays role in lipid metabolism and inflammation in liver, skeletal muscle, and adipose tissue in obesity induced by high-fat diet (HFD); here, Mtmr14 deficiency in knockout mice accelerates HFD-induced inflammation and metabolic dysfunction (obesity, hyperglycemia, and hyperlipidemia).

  2. propose that defect of MTMR14 promotes autophagy and cell proliferation in MEFs

  3. In young Mtmr14 KO mice (12 weeks). The T-tubule dysmorphology (swollen and elongated) could explain, in part, the defects in Ca2thorn excitationcontraction machinery observed in previous studies.

  4. MTMR14 may play an important role in muscle calcium homeostasis.

  5. Data report that mice deficient in the newly identified phosphatidylinositol phosphate phosphatase MIP (show MIP ELISA Kits)/MTMR14 (muscle-specific (show EIF3K ELISA Kits) inositol phosphatase) show muscle weakness and fatigue.

Myotubularin Related Protein 14 (MTMR14) Antigen Profile

Antigen Summary

This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.

Alternative names and synonyms associated with Myotubularin Related Protein 14 (MTMR14)

  • myotubularin related protein 14 (mtmr14) Elisa Kit
  • myotubularin related protein 14 (MTMR14) Elisa Kit
  • myotubularin related protein 14 (Mtmr14) Elisa Kit
  • 1110061O04Rik Elisa Kit
  • AW553738 Elisa Kit
  • C3orf29 Elisa Kit
  • C76151 Elisa Kit
  • fc14d11 Elisa Kit
  • jumpy Elisa Kit
  • MGC131146 Elisa Kit
  • RGD1304842 Elisa Kit
  • wu:fc14d11 Elisa Kit

Protein level used designations for MTMR14

myotubularin related protein 14 , myotubularin-related protein 14-like , HCV NS5A-transactivated protein 4 splice variant A-binding protein 1 , NS5ATP4ABP1 , egg-derived tyrosine phosphatase homolog , jumpy , myotubularin-related protein 14 , mJumpy

GENE ID SPECIES
323929 Danio rerio
703936 Macaca mulatta
734951 Xenopus laevis
100014047 Monodelphis domestica
100036693 Xenopus (Silurana) tropicalis
100224025 Taeniopygia guttata
100397575 Callithrix jacchus
100542441 Meleagris gallopavo
100554543 Anolis carolinensis
64419 Homo sapiens
97287 Mus musculus
312634 Rattus norvegicus
484668 Canis lupus familiaris
416048 Gallus gallus
100157480 Sus scrofa
514596 Bos taurus
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