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analysis of essential residues of PIG-W and Gwt1p and membrane topology of Gwt1p
Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003
, phosphatidylinositol glycan, class W
, phosphatidylinositol-glycan biosynthesis class W protein