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two of these isoforms, sPLA2 IIA (show PLA2G2A Proteins) and sPLA2 IIF, localize to the upper stratum granulosum and increase in response to experimental barrier perturbation.
Ethanolamine lysoplasmalogen, a PLA2G2F-derived marker product, rescued defective activation of Pla2g2f(-/-) keratinocytes both in vitro and in vivo
PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Hydrolyzes phosphatidylglycerol versus phosphatidylcholine with a 15-fold preference.
, group IIF secretory phospholipase A2
, phosphatidylcholine 2-acylhydrolase 2F