Browse our phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) Proteins (PLA2G4A)

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phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) Proteins (PLA2G4A)
On www.antibodies-online.com are 9 phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A) Proteins from 6 different suppliers available. Additionally we are shipping phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) Antibodies (114) and phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) Kits (41) and many more products for this protein. A total of 174 phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) products are currently listed.
Synonyms:
cPLA2, cPLA2-alpha, cPLA2alpha, PLA2, Pla2c, PLA2G1B, Pla2g4, PLA2G4A
list all proteins Gene Name GeneID UniProt
PLA2G4A 18783 P47713
PLA2G4A 5321 P47712
PLA2G4A 24653  

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phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) Proteins (PLA2G4A) by Origin

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More Proteins for phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) Interaction Partners

Pig (Porcine) phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A) interaction partners

  1. Data show that glycation end products (AGE) increase PIP2 production, arachidonic acid release and reactive oxygen species via cytosolic phospholipase A2 activation, and inhibit Na+ K+ ATPase (show ATP1A1 Proteins) surface expression via PIP5Kgamma (show PIP5K1C Proteins).

Mouse (Murine) phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A) interaction partners

  1. Data suggest that the ability of pyrrophenone to block endoplasmic reticulum (ER) calcium release is an off-target effect since it occurs in fibroblasts lacking cytosolic phospholipase A2alpha (cPLA2alpha).

  2. these results show that preadipocyte cPLA2alpha activation is a hitherto unrecognized factor for adipogenesis in vitro and in vivo.

  3. The data emphasize the importance of the PLCeta2 EF-hand domain and articulation of PLCeta2 with LIMK-1 (show LIMK1 Proteins) in regulating neuritogenesis.

  4. show that accumulation of Abeta (show APP Proteins) induced elevation of APP (show APP Proteins) protein expression mediated by cPLA2 alpha, PGE2 release, and CREB (show CREB1 Proteins) activation via protein kinase A pathway

  5. Prostaglandins from cPLA2-alpha/COX1 pathway and mitogen-activated protein kinases regulate gene expression in Candida albicans-infected macrophages.

  6. Thymocyte maturation can occur independently of cPLA2-alpha.

  7. The study reports the formation of a multiprotein complex at the G2-to-M transition in vitro and in vivo. Group IVA cytosolic phospholipase A2 (cPLA2-alpha) acts as a bridge in this complex to promote binding of SIRT2 (show SIRT2 Proteins) to cyclin A (show CCNA2 Proteins)-Cdk2 (show CDK2 Proteins).

  8. osteoblastic cytosolic phospholipase A2 is crucially involved in ET-1 (show EDN1 Proteins)-induced prostaglandin formation.

  9. Data indicate that cytosolic phospholipase A2alpha (cPLA2alpha) mediates interleukin 6 (IL6 (show IL6 Proteins)) induction by Pseudomonas aeruginosa pulmonary infection.

  10. our data indicate that SR-A (show MSR1 Proteins) localizes in LRs (show LARS Proteins) and that LRs (show LARS Proteins) are required to couple SR-A (show MSR1 Proteins) to PLA2 (show PLA2G2A Proteins) activation during SRA (show MSR1 Proteins)-mediated macrophage attachment.

Human phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A) interaction partners

  1. Phospholipase activity is linked to energy metabolism, revealing cPLA2 as a central regulator of both lipidomics and energy flux.

  2. present study indicates that among all cytosolic phospholipases A2, specific phospholipase A2 group IVA are the main enzymes involved in cigarette smoke induced anomalies in type I and type II lung epithelial cells

  3. genetic association study in Quebec City population: Data suggest total plasma n-6 fatty acid phospholipid levels and C-reactive protein (show CRP Proteins) are modulated by SNPs in PLA2G4A and PLA2G6 (show PLA2G6 Proteins) alone or in combination with fish oil dietary supplementation.

  4. cPLA2alpha plays an important role in cell cycle re-entry by quiescent prostate cancer cells

  5. Thymocyte maturation can occur independently of cPLA2-alpha.

  6. These studies constitute a definitive account, demonstrating the fundamental role of cPLA2alpha to eicosanoid formation and cellular responses within the human circulation.

  7. The study reports the formation of a multiprotein complex at the G2-to-M transition in vitro and in vivo. Group IVA cytosolic phospholipase A2 (cPLA2-alpha) acts as a bridge in this complex to promote binding of SIRT2 (show SIRT2 Proteins) to cyclin A (show CCNA2 Proteins)-Cdk2 (show CDK2 Proteins).

  8. EGF (show EGF Proteins) stimulates platelet-activating factor production in ovarian cancer cells in a manner that requires cPLA2.

  9. We conclude that cPLA2alpha is required for sustaining AKT (show AKT1 Proteins) phosphorylation at Ser473 and cell proliferation in colorectal cancer cells with PI3K (show PIK3CA Proteins) mutation

  10. alphaSN triggered synapse damage via hyperactivation of cPLA2

Cow (Bovine) phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A) interaction partners

  1. result suggests that cPLAPgamma may act as a G protein, activating cPLA(2)alpha prior to reaching full intracellular Ca(2 (show CA2 Proteins) ) concentrations

  2. Ovulation is associated with an LH/hCG (show CGA Proteins)-dependent induction of PLA2G4A in GC via the adenylyl cyclase/cAMP pathway.

  3. Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin (show F2 Proteins)-induced smooth muscle cell proliferation.

Horse (Equine) phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A) interaction partners

  1. The results indicate that PLA2 (show YWHAZ Proteins) activity in equine endometrium changes with the stage of the oestrous cycle and thus may be influenced by systemic hormone concentrations.

  2. During pregnancy, PLA2 (show YWHAZ Proteins) expression may be sufficient to initiate the cascade for prostaglandin f2alpha secretion and does not play a direct role in maternal recognition of pregnancy.

phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A) Protein Profile

Protein Summary

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

Alternative names and synonyms associated with phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A)

  • cytosolic phospholipase a2 (cpla2)
  • cytosolic phospholipase A2-like (LOC100520687)
  • phosphatidyl choline 2-acylhydrolase cPLA2 (LOC100008748)
  • phospholipase A2, group IVA (cytosolic, calcium-dependent) (Pla2g4a)
  • phospholipase A2, group IVA (cytosolic, calcium-dependent) (PLA2G4A)
  • phospholipase A2, group IVA (cytosolic, calcium-dependent) (pla2g4a)
  • cPLA2 protein
  • cPLA2-alpha protein
  • cPLA2alpha protein
  • PLA2 protein
  • Pla2c protein
  • PLA2G1B protein
  • Pla2g4 protein
  • PLA2G4A protein

Protein level used designations for PLA2G4A

cytosolic phospholipase A2 , phospholipase A2 group IVA , Phospholipase A2 group IVA , Cytosolic phospholipase A2 (CPLA2) , Type IV PLA2 , cPLA2-alpha , cytosolic PLA2 , phospholipase A2, group 4 , cPLA2 , calcium-dependent phospholipid-binding protein , lysophospholipase , phosphatidylcholine 2-acylhydrolase , phospholipase A2 cytosolic , phospholipase A2, group IB (pancreas)

GENE ID SPECIES
30554 Danio rerio
100520687 Sus scrofa
100008748 Oryctolagus cuniculus
18783 Mus musculus
5321 Homo sapiens
24653 Rattus norvegicus
525072 Bos taurus
396394 Gallus gallus
100033889 Equus caballus
480048 Canis lupus familiaris
101111472 Ovis aries
380561 Xenopus laevis
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