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murine cytosolic phospholipases A2 delta, epsilon, and zeta form a gene cluster with cPLA(2 (show PLA2G4A ELISA Kits))beta
The findings suggest that PLA2 (show YWHAZ ELISA Kits) inhibition or CD1a (show CD1A ELISA Kits) blockade may have therapeutic potential for psoriasis.
study defined eight additional recurrently mutated genes in SMZL; these genes are CREBBP (show CREBBP ELISA Kits), CBFA2T3 (show CBFA2T3 ELISA Kits), AMOTL1 (show AMOTL1 ELISA Kits), FAT4, FBXO11 (show FBXO11 ELISA Kits), PLA2G4D, TRRAP (show TRRAP ELISA Kits) and USH2A (show USH2A ELISA Kits).
cPLA(2 (show PLA2G4A ELISA Kits))delta exhibits a unique distribution pattern compared with that of known cPLA(2 (show PLA2G4A ELISA Kits)) subtypes and may play a critical role in inflammation in psoriatic lesions
The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004
, cytosolic phospholipase A2 delta
, phospholipase A2 delta, cytosolic
, phospholipase A2 group IVD