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anti-Mouse (Murine) ITGA5 Antibodies:
anti-Human ITGA5 Antibodies:
anti-Rat (Rattus) ITGA5 Antibodies:
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Mouse (Murine) Monoclonal ITGA5 Primary Antibody for BR, IHC (fro) - ABIN2689316
Cukierman, Pankov, Stevens, Yamada: Taking cell-matrix adhesions to the third dimension. in Science (New York, N.Y.) 2001
Show all 9 Pubmed References
Mouse (Murine) Monoclonal ITGA5 Primary Antibody for BR, IHC (f) - ABIN1176992
Gomez, Cano: Expression of beta 1 integrin receptors in transformed mouse epidermal keratinocytes: upregulation of alpha 5 beta 1 in spindle carcinoma cells. in Molecular carcinogenesis 1995
Show all 8 Pubmed References
Mouse (Murine) Monoclonal ITGA5 Primary Antibody for FACS - ABIN2689318
Halvorson, Coligan: Enhancement of VLA integrin receptor function on thymocytes by cAMP is dependent on the maturation stage of the thymocytes. in Journal of immunology (Baltimore, Md. : 1950) 1995
Show all 6 Pubmed References
Human Monoclonal ITGA5 Primary Antibody for IHC (fro), FACS - ABIN920557
Klingemann, Dedhar: Distribution of integrins on human peripheral blood mononuclear cells. in Blood 1989
Show all 5 Pubmed References
Human Monoclonal ITGA5 Primary Antibody for IF, IP - ABIN968077
Alahari, Lee, Juliano: Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration. in The Journal of cell biology 2001
Show all 5 Pubmed References
Human Monoclonal ITGA5 Primary Antibody for IF, IP - ABIN968078
Sottile, Hocking: Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions. in Molecular biology of the cell 2002
Show all 5 Pubmed References
Mouse (Murine) Monoclonal ITGA5 Primary Antibody for FACS, IP - ABIN2689315
Narumiya, Abe, Kita, Miyake, Nakajima, Watanabe, Oka, Sugiyama, Yagita, Okumura: Pre-B cells adhere to fibronectin via interactions of integrin alpha 5/alpha V with RGDS as well as of integrin alpha 4 with two distinct V region sequences at its different binding sites. in International immunology 1994
Show all 4 Pubmed References
Human Monoclonal ITGA5 Primary Antibody for FACS, IHC - ABIN969221
Jones, Gockerman, Busby, Wright, Clemmons: Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence. in Proceedings of the National Academy of Sciences of the United States of America 1993
Show all 5 Pubmed References
Human Polyclonal ITGA5 Primary Antibody for IF (p), IHC (p) - ABIN670221
Cui, Xu, Ma, Gao, Liu, Yue, Wu: The role of integrin-?5 in the proliferation and odontogenic differentiation of human dental pulp stem cells. in Journal of endodontics 2014
Show all 3 Pubmed References
Human Monoclonal ITGA5 Primary Antibody for Func, FACS - ABIN1177342
Tran Van Nhieu, Isberg: Bacterial internalization mediated by beta 1 chain integrins is determined by ligand affinity and receptor density. in The EMBO journal 1993
Show all 2 Pubmed References
results suggest that Edil3 may stimulate osteoblast differentiation and matrix mineralization by increasing expression of Runx2 (show RUNX2 Antibodies) through alpha5beta1 integrin /ERK (show EPHB2 Antibodies) pathway
KCNB1 (show KCNB1 Antibodies) and integrin alpha chain (show FCGRT Antibodies) V (integrin-alpha5) coimmunoprecipitated in the mouse brain and these interactions were retained upon channel's oxidation.
We demonstrate that AnkB binds to Rab GTPase Activating Protein 1-Like (RabGAP1L) and recruits it to PI3P-positive organelles, where RabGAP1L inactivates Rab22A, and promotes polarized trafficking to the leading edge of migrating fibroblasts. We further determine that a5b1-integrin depends on an AnkB/RabGAP1L complex for polarized recycling
Osteoprotegerin (show TNFRSF11B Antibodies) facilitates pulmonary arterial hypertension pathogenesis by regulating pulmonary arterial smooth muscle cell proliferation via integrin alphavbeta3 (show ITGAV Antibodies)/FAK (show PTK2 Antibodies)/AKT (show AKT1 Antibodies) signaling pathway.
FAK sustained the active integrin conformation by maintaining talin association with Rab11 endosomes in a type I phosphatidylinositol phosphate kinase (PIPKIgamma)-dependent manner.
cells on fibronectin (show FN1 Antibodies) suppressed cAMP via enhanced phosphodiesterase (PDE (show TWIST1 Antibodies)) activity, through direct binding of integrin alpha5 to phosphodiesterase-4D5
this study shows that protective effect of osteopontin (show SPP1 Antibodies) results from integrin-alpha5-dependent enhancement of neutrophil migration and accumulation at sites of infection
Gdf-5 (show GDF5 Antibodies) induced the expression of the alpha5 sub-unit, while Bmp-7 (show BMP7 Antibodies) induced the expression of the alphaV sub-unit.
EGFR (show EGFR Antibodies) activation can be regulated by the N-glycosylation of integrin alpha5, which is a novel molecular paradigm for the cross-talk between integrins and growth factor receptors
An (as yet unknown) integrin alpha5-dependent signal extrinsic to the pharyngeal endothelium mediates the formation of the 4th pharyngeal arch arteries through fibronectin (show FN1 Antibodies).
Inhibiting Fgf-R (show FGFR2 Antibodies) partly reversed alphavbeta3 integrin activity in Mll (show MLL Antibodies)-Ell (show ELL Antibodies)+ progenitor cells.
alpha5beta1 integrin can stimulate drug resistance in cancer cells via a mechanism based on inhibition of protein kinase (show CDK7 Antibodies) Erk (show EPHB2 Antibodies).
We measured the effect of recombinant Gal-3 (show LGALS3 Antibodies) added exogenously on the lateral mobility of the alpha5b1 integrin on HeLa cells. Using single-particle tracking (SPT (show AGXT Antibodies)) we detected increased lateral mobility of the integrin in the presence of Gal-3 (show LGALS3 Antibodies), while its truncated C-terminal domain (Gal (show GAL Antibodies)-3C) showed only minor reductions in lateral mobility.
Eps8 (show EPS8 Antibodies)/Abi1 (show ABI1 Antibodies)/Sos1 (show SOS1 Antibodies) tricomplex acts as a key molecular switch altering the balance between Rac1 and Rho activation; its presence or absence in pancreatic ductal adenocarcinoma cells modulates alphavbeta6-dependent functions, resulting in a pro-migratory (Rac1-dependent) or a pro-TGF-beta1 (show TGFB1 Antibodies) activation (Rho-dependent) functional phenotype.
Findings indicate integrin inhibition as a promising strategy to block both aryl hydrocarbon receptor (AhR (show AHR Antibodies)) and transforming growth factor beta (TGF-beta)-controlled features of malignancy in glioblastoma.
Suggest an adhesion-dependent mechanism of RUNX2 (show RUNX2 Antibodies) for the osteotropism and bone colonization of breast cancer cells and implicate RUNX2 (show RUNX2 Antibodies) and integrin alpha5 as potential molecular markers for the prediction of bone metastasis.
cells on fibronectin (show FN1 Antibodies) suppressed cAMP via enhanced phosphodiesterase (PDE (show ALDH7A1 Antibodies)) activity, through direct binding of integrin alpha5 to phosphodiesterase-4D5
Data show that high mobility group nucleosomal binding domain 2 (HMGN2 (show HMGN2 Antibodies)) knockdown induced the increased expression of alpha5beta1 integrin on cell membranes, which resulted in a significant increase in Klebsiella pneumoniae internalization.
ITGA5 expression is significantly upregulated in human masticatory mucosa during wound healing
Putative function of fibronectin (show FN1 Antibodies) and its receptor (integrin alpha(5)beta(1)) in male and female gametes during bovine fertilization in vitro.
Results indicate that XIAP (show XIAP Antibodies) stabilizes the alpha(5)-integrin-associated focal adhesion complex, thereby further regulating endothelial cell adhesion and migration.
alphavbeta3 integrin engagement in vascular endothelium regulates Ca2 (show CA2 Antibodies)+-dependent K+ current
Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
, CD49 antigen-like family member E
, fibronectin receptor alpha polypeptide
, fibronectin receptor subunit alpha
, integrin alpha-5
, integrin alpha-F
, fibronectin receptor, alpha subunit
, very late activation protein 5, alpha subunit
, integrin alpha 5 (fibronectin receptor alpha)