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Browse our SMAD7 (SMAD7) ELISA Kits

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SMAD, Mothers Against DPP Homolog 7 ELISA Kits (SMAD7)
On are 40 SMAD, Mothers Against DPP Homolog 7 (SMAD7) ELISA Kits from 8 different suppliers available. Additionally we are shipping SMAD7 Antibodies (89) and SMAD7 Proteins (5) and many more products for this protein. A total of 140 SMAD7 products are currently listed.
CRCS3, madh7, MADH8, Smad7a, Smad10, xsmad7
list all ELISA KIts Gene Name GeneID UniProt
SMAD7 4092 O15105
SMAD7 17131 O35253
SMAD7 81516 O88406

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Top referenced SMAD7 ELISA Kits

  1. Human SMAD7 ELISA Kit for Sandwich ELISA - ABIN414598 : Piotrowski, Kiszałkiewicz, Górski, Antczak, Górski, Pastuszak-Lewandoska, Migdalska-Sęk, Domańska-Senderowska, Nawrot, Czarnecka, Kurmanowska, Brzeziańska-Lasota: Immunoexpression of TGF-β/Smad and VEGF-A proteins in serum and BAL fluid of sarcoidosis patients. in BMC immunology 2015 (PubMed)

More ELISA Kits for SMAD7 Interaction Partners

Human SMAD, Mothers Against DPP Homolog 7 (SMAD7) interaction partners

  1. the findings show that TIEG1 is highly expressed in human keloids and that it directly binds and represses Smad7 promoter-mediated activation of TGF-beta (show TGFB1 ELISA Kits)/Smad2 (show SMAD2 ELISA Kits) signaling

  2. A significant association was found between the low expression of inhibitory protein SMAD-7 and both zeta-chain-associated protein kinase (show CDK7 ELISA Kits) 70-negative cells (p = 0.04) and lower apoptotic index (p = 0.004). No differences were observed in SMAD-2 (show SMAD2 ELISA Kits)/3 expression. In conclusion, our results demonstrate a significant correlation between greater SMAD-1 (show GARS ELISA Kits)/8 and lower SMAD-4 (show SMAD4 ELISA Kits) expression in chronic lymphocytic leukemia cells

  3. miRNA-181a appears to play a potential role in pancreatic beta-cells dysfunction via SMAD7.

  4. Carboplatin may upregulate SMAD7 through suppression of miR (show MLXIP ELISA Kits)-21 to inhibit TGFbeta (show TGFB1 ELISA Kits) receptor signaling mediated non-small cell lung cancer cell invasion.

  5. Downregulation of Smad 7 promotes migration and invasion through enhancing epithelial mesenchymal transition in esophageal squamous cell carcinoma.

  6. miR (show MLXIP ELISA Kits)-424-5p -SMAD7 pathway contributed to esophageal squamous cell carcinoma invasion and metastasis.

  7. Polymorphisms in the SMAD7 rs4939827 is associated with rectal cancer.

  8. microRNA-497 modulates breast cancer cell proliferation, invasion, and survival by targeting SMAD7.

  9. SMAD7 overexpression might represent a mechanism limiting TGF-beta (show TGFB1 ELISA Kits)-mediated fibrogenesis in human hepatic diseases; therefore, SMAD7 induction likely represents a candidate for novel therapeutic approaches.

  10. Data show that protein kinase (show CDK7 ELISA Kits) LKB1 (show STK11 ELISA Kits) physically interacts with BMP type I receptors and requires Smad7 protein to promote downregulation of the receptor.

Mouse (Murine) SMAD, Mothers Against DPP Homolog 7 (SMAD7) interaction partners

  1. results indicate that miR (show MLXIP ELISA Kits)-181a-5p promotes 3T3-L1 preadipocyte differentiation and adipogenesis through regulating TGFbeta (show TGFB1 ELISA Kits)/Smad (show SMAD1 ELISA Kits) and Wnt (show WNT2 ELISA Kits) signaling pathway by directly targeting Smad7 and Tcf7l2 (show TCF7L2 ELISA Kits)

  2. microRNA-497 modulates breast cancer cell proliferation, invasion, and survival by targeting SMAD7.

  3. results indicate that miR (show MLXIP ELISA Kits)-195a-5p inhibits MTEC1 proliferation, at least in part, via down-regulation of Smad7

  4. Data indicate that, in irritable bowel disease, high Smad7 contributes to sustain detrimental immune responses and knockdown of this molecule can help attenuate the ongoing mucosal inflammation in patients with such disorders

  5. Hic-5 (show TGFB1I1 ELISA Kits) deficiency attenuates the activation of hepatic stellate cells and liver fibrosis though reducing the TGF-beta (show TGFB1 ELISA Kits)/Smad2 (show SMAD2 ELISA Kits) signaling by upregulation of Smad7

  6. Data show that microRNA miR (show MLXIP ELISA Kits)-21 was significantly upregulated by bone morphogenetic protein 9 (BMP9 (show GDF2 ELISA Kits)) during the osteogenesis the multilineage cells (MMCs) by suppressing Smad7 protein.

  7. Genetic disruption of Smad7 impairs skeletal muscle growth and regeneration

  8. The present study also identified for the first time, to the best of our knowledge, the promotion of osteogenic differentiation and mineralization by miR (show MLXIP ELISA Kits)-21, by repressing the expression of Smad7.

  9. Overexpression of Smad7 in human HaCaT keratinocyte cells and mouse skin tissues elevated EGF receptor (EGFR (show EGFR ELISA Kits)) activity by impairing ligand-induced ubiquitination and degradation of activated receptor, which is induced by the E3 ubiquitin ligase c-Cbl (show CBL ELISA Kits).

  10. Smad7 signaling is repressed by the active form of vitamin D, 1,25-dihydroxyvitamin D3, which also activates ERK (show EPHB2 ELISA Kits) to inhibit the differentiation of an inflammatory T helper cell subset and suppress experimental autoimmune encephalomyelitis

Xenopus laevis SMAD, Mothers Against DPP Homolog 7 (SMAD7) interaction partners

  1. cTid1 can bind to other members of the Smad (show SMAD1 ELISA Kits) family and that highest binding activity occurs with the negative regulatory Smad7, through the conserved MH2 (show SCN4A ELISA Kits) domain

  2. Smad7 has a role in Xenopus mesodermal and neural induction

Pig (Porcine) SMAD, Mothers Against DPP Homolog 7 (SMAD7) interaction partners

  1. SMAD7 plays a potentially important role in mammalian prenatal skeletal muscle development and is a candidate gene for promoting greater weaning weight in pig breeding.

  2. MiR (show MYLIP ELISA Kits)-92a inhibits porcine ovarian granulosa cell apoptosis by targeting Smad7 gene

Cow (Bovine) SMAD, Mothers Against DPP Homolog 7 (SMAD7) interaction partners

  1. a detailed computational model for TGF-beta (show TGFB1 ELISA Kits) signalling that incorporates elements of previous models together with crosstalking between Smad1 (show SMAD1 ELISA Kits)/5/8 and Smad2 (show SMAD2 ELISA Kits)/3 channels through a negative feedback loop dependent on Smad7.

  2. Results suggest that myostatin (show MSTN ELISA Kits) auto-regulates its gene expression through a Smad7 dependent mechanism in myogenic cells.

SMAD7 Antigen Profile

Antigen Summary

The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SMAD7

  • SMAD family member 7 (SMAD7) Elisa Kit
  • SMAD family member 7 (Smad7) Elisa Kit
  • SMAD family member 7 (smad7) Elisa Kit
  • CRCS3 Elisa Kit
  • madh7 Elisa Kit
  • MADH8 Elisa Kit
  • Smad7a Elisa Kit
  • Smad10 Elisa Kit
  • xsmad7 Elisa Kit

Protein level used designations for SMAD7

MAD (mothers against decapentaplegic, Drosophila) homolog 7 , MAD homolog 8 , Mothers against decapentaplegic, drosophila, homolog of, 7 , SMAD, mothers against DPP homolog 7 , hSMAD7 , mothers against DPP homolog 8 , mothers against decapentaplegic homolog 7 , MAD homolog 7 , SMAD 7 , madh8 , mothers against DPP homolog 7 , mothers against decapentaplegic homolog 8 , MAD, mothers against decapentaplegic homolog 7 , mothers against DPP 7 , mothers against decapentaplegic-like protein 7 , SMAD family member 7

4092 Homo sapiens
17131 Mus musculus
81516 Rattus norvegicus
490570 Canis lupus familiaris
394331 Xenopus laevis
455411 Pan troglodytes
100717293 Cavia porcellus
100521305 Sus scrofa
535916 Bos taurus
429683 Gallus gallus
443160 Ovis aries
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