Browse our anti-Egl Nine Homolog 2 (C. Elegans) (EGLN2) Antibodies

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anti-Egl Nine Homolog 2 (C. Elegans) Antibodies (EGLN2)
On are 127 Egl Nine Homolog 2 (C. Elegans) (EGLN2) Antibodies from 16 different suppliers available. Additionally we are shipping Egl Nine Homolog 2 (C. Elegans) Proteins (9) and many more products for this protein. A total of 146 Egl Nine Homolog 2 (C. Elegans) products are currently listed.
0610011A13Rik, C85656, egln2, EIT6, Hif-p4h-1, HIF-PH1, HIFPH1, HPH-1, HPH-3, Ier4, PHD-1, Phd1, phd2, SM-20

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Top referenced anti-Egl Nine Homolog 2 (C. Elegans) Antibodies

  1. Human Polyclonal EGLN2 Primary Antibody for EM, ICC - ABIN151776 : Li, Yi, Sundy, Chen, Hilliker, Donley, Muldoon, Li: Expression and actions of HIF prolyl-4-hydroxylase in the rat kidneys. in American journal of physiology. Renal physiology 2007 (PubMed)
    Show all 39 references for 151776

  2. Human Polyclonal EGLN2 Primary Antibody for EIA, WB - ABIN952039 : Winning, Splettstoesser, Fandrey, Frede: Acute hypoxia induces HIF-independent monocyte adhesion to endothelial cells through increased intercellular adhesion molecule-1 expression: the role of hypoxic inhibition of prolyl hydroxylase activity for the induction of NF-kappa B. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 2 references for 952039

  3. Dog (Canine) Polyclonal EGLN2 Primary Antibody for WB - ABIN2778438 : Pan, Mansfield, Bertozzi, Rudenko, Chan, Giaccia, Simon: Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro. in Molecular and cellular biology 2007 (PubMed)
    Show all 2 references for 2778438

  4. Human Polyclonal EGLN2 Primary Antibody for EIA, WB - ABIN453633 : Semenza: HIF-1, O(2), and the 3 PHDs: how animal cells signal hypoxia to the nucleus. in Cell 2001 (PubMed)
    Show all 2 references for 453633

  5. Human Polyclonal EGLN2 Primary Antibody for FACS, IHC (p) - ABIN652648 : Aprelikova, Pandolfi, Tackett, Ferreira, Salnikow, Ward, Risinger, Barrett, Niederhuber: Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response. in Cancer research 2009 (PubMed)

  6. Cow (Bovine) Polyclonal EGLN2 Primary Antibody for WB - ABIN2775821 : Appelhoff, Tian, Raval, Turley, Harris, Pugh, Ratcliffe, Gleadle: Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor. in The Journal of biological chemistry 2004 (PubMed)

  7. Cow (Bovine) Polyclonal EGLN2 Primary Antibody for WB - ABIN2775992 : Gilbert, Banek, Bauer, Gingery, Needham: Exercise training attenuates placental ischemia-induced hypertension and angiogenic imbalance in the rat. in Hypertension 2012 (PubMed)

More Antibodies against Egl Nine Homolog 2 (C. Elegans) Interaction Partners

Xenopus laevis Egl Nine Homolog 2 (C. Elegans) (EGLN2) interaction partners

  1. comparative analysis of phd1, 2, and 3 expression in Xenopus laevis

Mouse (Murine) Egl Nine Homolog 2 (C. Elegans) (EGLN2) interaction partners

  1. Phd1 deficiency in dendritic cells significantly reduced interleukin-1beta production in response to lipopolysaccharide. Taken together, our results further support the development of selective PHD1 inhibitors for ulcerative colitis, and identify haematopoietic cells as their primary target.

  2. PHD1 deficiency promotes hepatic steatosis and liver-specific insulin (show INS Antibodies) resistance but does not worsen the deleterious effects of HFD on metabolic homeostasis.

  3. deleting Phd1-3 genes in osteoblasts increased osteoclast formation in vitro and in bone.

  4. These data identify PHD1 as a regulator of neuronal metabolism and a potential therapeutic target in ischemic stroke.

  5. PHD1 and PHD3 (show EGLN3 Antibodies) deletions promote angiogenesis in ischemia-injured tissue by increasing HIF1-alpha (show HIF1A Antibodies) stability.

  6. Rosiglitazone increases PHD (show PDC Antibodies) expression in a PPARgamma (show PPARG Antibodies)-dependent manner and that this leads to the commitment of anti-adipogenic proteins to the ubiquitination-proteasomal pathway and to the subsequent induction of adipocyte differentiation.

  7. PHD-1 deficient mouse appears to be the first animal model showing neuroepithelial bodies cell hyperplasia

  8. Alterations in the function of all 3 isoforms of prolyl-4-hydroxylase enzymes (PHD1-3) in the first 24 h following transient focal cerebral ischaemia are reported.

  9. Data show it is feasible to reactivate hepatic erythropoietin (show EPO Antibodies) production using systemically delivered siRNAs targeting the EglN1 (show EGLN1 Antibodies), EglN2 and EglN3 (show EGLN3 Antibodies) prolyl hydroxylase mRNA specifically in the liver.

  10. silencing of PHD-1 attenuates myocardial ischemia/reperfusion injury probably by enhancing HIF-1alpha (show HIF1A Antibodies)/beta-catenin (show CTNNB1 Antibodies)/endothelial nitric oxide synthase (show NOS3 Antibodies)/nuclear factor-kappaB and Bcl-2 (show BCL2 Antibodies) signaling pathway

Human Egl Nine Homolog 2 (C. Elegans) (EGLN2) interaction partners

  1. PHD1 is phosphorylated by CDK2 (show CDK2 Antibodies), CDK4 (show CDK4 Antibodies) and CDK6 (show CDK6 Antibodies) at Serine 130.

  2. siRNA-mediated knockdown of PHD1 inhibited glucose-stimulated insulin (show INS Antibodies) secretion in pancreatic Beta cells.

  3. EglN2 associates with the NRF1 (show NFE2L1 Antibodies)-PGC1alpha complex and controls mitochondrial function in breast cancer

  4. rs3733829 in the EGLN2 gene is significantly associated with the risk of COPD (show ARCN1 Antibodies) in Chinese populations of Hainan province.

  5. Germ-line PHD1 and PHD2 (show EGLN1 Antibodies) mutations detected in patients with pheochromocytoma/paraganglioma-polycythemia

  6. study conducted to investigate the association between gastric cancer (GC) susceptibility with a 4-bp insertion/deletion polymorphism (rs10680577) in the proximal promoter of EGLN2; findings showed that the heterozygote and the homozygote 4-bp del/del confer a significantly increased risk of GC

  7. Data indicate that the prolyl hydrolase 1 (PHD1) rs10680577 polymorphism is associated with the risk of non-small cell lung cancer in a Chinese population.

  8. PHD-1 played an important role in hypoxic response pathway of trophoblast through modulating the level of HIF-2alpha (show EPAS1 Antibodies).

  9. PHD1 could induce cell cycle arrest in lung cancer cells, resulting in the suppression of cell proliferation.

  10. Results show that variants in two adjacent genes, EGLN2 and CYP2A6 (show CYP2A6 Antibodies), influence smoking behavior related to disease risk.

Egl Nine Homolog 2 (C. Elegans) (EGLN2) Antigen Profile

Antigen Summary

The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.

Alternative names and synonyms associated with Egl Nine Homolog 2 (C. Elegans) (EGLN2)

  • egl nine homolog 1 (egln1) antibody
  • egl nine homolog 2 (C. elegans) (EGLN2) antibody
  • Egl nine homolog 2 (egln2) antibody
  • egl nine homolog 2 (egln2) antibody
  • EGL nine homolog 2 (C. elegans) (Egln2) antibody
  • egl-9 family hypoxia-inducible factor 2 (EGLN2) antibody
  • 0610011A13Rik antibody
  • C85656 antibody
  • egln2 antibody
  • EIT6 antibody
  • Hif-p4h-1 antibody
  • HIF-PH1 antibody
  • HIFPH1 antibody
  • HPH-1 antibody
  • HPH-3 antibody
  • Ier4 antibody
  • PHD-1 antibody
  • Phd1 antibody
  • phd2 antibody
  • SM-20 antibody

Protein level used designations for EGLN2

EGL nine homolog 2 , egl nine homolog 2 , Egl nine homolog 2 , EGL nine (C.elegans) homolog 2 , egl nine homolog 2 (C. elegans) , egl nine homolog 2-like , HIF-PH1 , HIF-prolyl hydroxylase 1 , HPH-1 , falkor , hypoxia-inducible factor prolyl hydroxylase 1 , immediate early response 4 , prolyl hydroxylase domain-containing protein 1 , HIF-1alpha prolyl-4-hydroxylase-1 , estrogen-induced tag 6

548714 Xenopus (Silurana) tropicalis
100172704 Pongo abelii
100306807 Salmo salar
456049 Pan troglodytes
703083 Macaca mulatta
100523673 Sus scrofa
100584172 Nomascus leucogenys
100158265 Xenopus laevis
112406 Mus musculus
484495 Canis lupus familiaris
308457 Rattus norvegicus
536763 Bos taurus
112398 Homo sapiens
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