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Browse our anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2) Antibodies

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anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 Antibodies (MLL2)
On www.antibodies-online.com are 37 Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2) Antibodies from 11 different suppliers available. Additionally we are shipping Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 Kits (10) and and many more products for this protein. A total of 49 Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 products are currently listed.
Synonyms:
AAD10, ALR, BC032281, BC058659, C430014K11Rik, CAGL114, GSTO1, HRX2, im:7157663, KABUK1, KMS, KMT2B, MLL1B, Mll2, Mll4, TNRC21, TRX2, WBP7
list all antibodies Gene Name GeneID UniProt
Anti-Rat MLL2 MLL2 27100 Q63042
MLL2 9757 Q9UMN6
MLL2 381022  

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Most Popular Reactivities for anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2) Antibodies

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Top referenced anti-Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 Antibodies

  1. Human Polyclonal MLL2 Primary Antibody for IHC, ELISA - ABIN184880 : Prasad, Zhadanov, Sedkov, Bullrich, Druck, Rallapalli, Yano, Alder, Croce, Huebner, Mazo, Canaani: Structure and expression pattern of human ALR, a novel gene with strong homology to ALL-1 involved in acute leukemia and to Drosophila trithorax. in Oncogene 1997 (PubMed)

  2. Human Monoclonal MLL2 Primary Antibody for ELISA, WB - ABIN948660 : Micale, Augello, Maffeo, Selicorni, Zucchetti, Fusco, De Nittis, Pellico, Mandriani, Fischetto, Boccone, Silengo, Biamino, Perria, Sotgiu, Serra, Lapi, Neri, Ferlini, Cavaliere, Chiurazzi, Monica et al.: Molecular analysis, pathogenic mechanisms, and readthrough therapy on a large cohort of Kabuki syndrome patients. ... in Human mutation 2014 (PubMed)

More Antibodies against Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 Interaction Partners

Human Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2) interaction partners

  1. The enzymatic activity of H3K4 methyltransferase MLL4 is required for its protein stability.

  2. We have reported a female Kabuki syndrome patient with typical dysmorphic features and developmental delay and a novel KMT2D mutation.

  3. Pygo2 (show PYGO2 Antibodies) functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.

  4. Mutation in the MLL2 gene is associated with Kabuki Syndrome.

  5. Mutations of the epigenetic genes KMT2D and KDM6A (show KDM6A Antibodies) cause dysregulation of certain developmental genes and account for the multiple congenital anomalies of the syndrome

  6. Data suggest that lysine methyltransferase 2D (KMT2D) mutations are rare in abdominal paraganglioma (PGLs (show PGLS Antibodies)).

  7. high proportion of recurrent somatic DICER1 (show DICER1 Antibodies) and KMT2D mutations in this series of sporadic IO-MEPL points to their likely important roles in the molecular pathogenesis of these rare embryonal tumors

  8. Whereas Set1 (show SETD1A Antibodies) targets are largely associated with the maintenance of the stem cell population, MLL1/2 targets are specifically enriched for genes involved in ciliogenesis.

  9. Although enhancer priming by MLL4/KMT2D is dispensable for cell-identity maintenance in mouse, it controls cell fate transition by orchestrating p300-mediated enhancer (show EP300 Antibodies)activation

  10. Our data suggest that MLL2 protein is overexpressed in primary gastrointestinal diffuse large B cell lymphoma and appears as a prognostic factor

Mouse (Murine) Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2) interaction partners

  1. Data from MLL4/KMT2D enzyme-dead knockin ES cells and mice indicate that the enzymatic activity of H3K4 methyltransferase MLL4 (show MLL4 Antibodies) is required for its protein stability.

  2. Although enhancer priming by H3K4me1/2 methyltransferase MLL4/KMT2D is dispensable for cell-identity maintenance, it controls cell fate transition by orchestrating p300 (show NOTCH1 Antibodies)-mediated enhancer activation

  3. KMT2D is essential for regulating cardiac gene expression during heart development primarily via H3K4 di-methylation

  4. MLL2 interacts with RNA polymerase II (RNAPII) and RECQL5, and, although MLL2 mutated cells have normal overall H3K4me levels in genes, nucleosomes in the immediate vicinity of RNAPII are hypomethylated.

  5. MLL4 (KMT2D) is a major H3K4 mono- and di-methyltransferase with partial functional redundancy with MLL3 (KMT2C) in mouse and human cells. MLL4 is enriched on enhancers and is required for enhancer activation, cell-type-specific gene expression and cell differentiation.

  6. Both MLL3 and MLL4 (show MLL4 Antibodies) complexes act as major epigenetic regulators of diverse metabolic processes (including circadian control of bile acid homeostasis).

  7. Mll2 (show MLL4 Antibodies), one of the six Set1 (show SETD1A Antibodies)/Trithorax (show MLLT1 Antibodies)-type H3K4 methyltransferases in mammals, is required for trimethylation of bivalent promoters in mouse embryonic stem cells, whereas Mll1 is redundant.

  8. results demonstrate that histone H3K4 methyltransferase Mll2 (show MLL4 Antibodies) is a component of the genetic regulation necessary for glucose homeostasis, resulting in a specific disease pattern linking chromatin modification with causes and progression of type 2 diabetes

  9. Reexpression of KMT2B (show MLL4 Antibodies) was sufficient to reinstate an active MagohB (show MAGOHB Antibodies) promoter.

  10. Arginine methylation of Pax7 (show PAX7 Antibodies) by Carm1 (show CARM1 Antibodies) functions as a molecular switch controlling the epigenetic induction of Myf5 (show MYF5 Antibodies) during satellite stem cell asymmetric division and entry into the myogenic program.

Pig (Porcine) Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2) interaction partners

  1. MLL2 is essential for porcine embryo development by the regulation of methylation of H3K4 in vitro.

Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2) Antigen Profile

Antigen Summary

The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.

Alternative names and synonyms associated with Myeloid/lymphoid Or Mixed-Lineage Leukemia 2 (MLL2)

  • lysine (K)-specific methyltransferase 2D (kmt2d) antibody
  • glutathione S-transferase omega-1-like (LOC785216) antibody
  • growth factor, augmenter of liver regeneration (Gfer) antibody
  • lysine (K)-specific methyltransferase 2B (KMT2B) antibody
  • lysine (K)-specific methyltransferase 2D (Kmt2d) antibody
  • lysine (K)-specific methyltransferase 2D (KMT2D) antibody
  • myeloid/lymphoid or mixed-lineage leukemia 2 (MLL2) antibody
  • myeloid/lymphoid or mixed-lineage leukemia 2-like (Mll2l) antibody
  • AAD10 antibody
  • ALR antibody
  • BC032281 antibody
  • BC058659 antibody
  • C430014K11Rik antibody
  • CAGL114 antibody
  • GSTO1 antibody
  • HRX2 antibody
  • im:7157663 antibody
  • KABUK1 antibody
  • KMS antibody
  • KMT2B antibody
  • MLL1B antibody
  • Mll2 antibody
  • Mll4 antibody
  • TNRC21 antibody
  • TRX2 antibody
  • WBP7 antibody

Protein level used designations for MLL2

myeloid/lymphoid or mixed-lineage leukemia 2 , glutathione S-transferase omega 1 , FAD-linked sulfhydryl oxidase ALR , augmenter of liver regeneration , growth factor, erv1 homolog , growth factor, erv1-like (augmenter of liver regeneration) , KMT2D , WBP-7 , WW domain binding protein 7 , WW domain-binding protein 7 , histone-lysine N-methyltransferase 2B , histone-lysine N-methyltransferase MLL4 , lysine N-methyltransferase 2B , lysine N-methyltransferase 2D , mixed lineage leukemia gene homolog 2 , myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 4 , myeloid/lymphoid or mixed-lineage leukemia 4 , myeloid/lymphoid or mixed-lineage leukemia protein 4 , trithorax homolog 2 , trithorax homologue 2 , ALL1-related protein , histone-lysine N-methyltransferase 2D , histone-lysine N-methyltransferase MLL2 , myeloid/lymphoid or mixed-lineage leukemia protein 2 , Kabuki make-up syndrome , Kabuki mental retardation syndrome , trinucleotide repeat containing 21

GENE ID SPECIES
100158249 Danio rerio
785216 Bos taurus
27100 Rattus norvegicus
9757 Homo sapiens
381022 Mus musculus
8085 Homo sapiens
506805 Bos taurus
100512962 Sus scrofa
486558 Canis lupus familiaris
425846 Gallus gallus
362996 Rattus norvegicus
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