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Nuclear Receptor Coactivator 3 ELISA Kits (NCOA3)
On are 11 Nuclear Receptor Coactivator 3 (NCOA3) ELISA Kits from 5 different suppliers available. Additionally we are shipping Nuclear Receptor Coactivator 3 Antibodies (158) and Nuclear Receptor Coactivator 3 Proteins (5) and many more products for this protein. A total of 177 Nuclear Receptor Coactivator 3 products are currently listed.
2010305B15Rik, actr, aib-1, aib1, AW321064, bHLHe42, cagh16, ctg26, kat13b, NCOA3, p/Cip, pcip, rac3, src-3, src3, tnrc14, tnrc16, tram-1, Tram1, xSRC-3
list all ELISA KIts Gene Name GeneID UniProt
NCOA3 8202 Q9Y6Q9
Mouse NCOA3 NCOA3 17979  
NCOA3 84584  

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Human Nuclear Receptor Coactivator 3 (NCOA3) interaction partners

  1. Data indicate that phosphorylated cortactin recruits Vav2 to activate Rac3 and promote invadopodial maturation in invasive breast cancer cells.

  2. Estrogen receptor (show ESR1 ELISA Kits) recruits steroid receptor coactivator (show SRA1 ELISA Kits)-3 primary coactivator and secondary coactivators, p300/CBP (show CREBBP ELISA Kits) and CARM1 (show CARM1 ELISA Kits) to regulate genetic transcription.

  3. we identify a positive feedback regulatory loop consisting of XBP1 (show XBP1 ELISA Kits) and NCOA3 that maintains high levels of NCOA3 and XBP1 (show XBP1 ELISA Kits) expression in breast cancer tissues.

  4. loss of miR-17 and miR (show MLXIP ELISA Kits)-20b enhanced breast cancer resistance to taxol by upregulating NCOA3 levels.

  5. Data (including data from studies of hydrogen-deuterium exchange coupled to mass spectrometry in presence of denaturants) suggest that, for peptide fragments of human ACTR and mouse Crebbp (show CREBBP ELISA Kits) representing disordered interaction domains, exchange rates are changed dramatically by high concentrations of denaturants guanidinium chloride or urea. (ACTR = activator of thyroid and retinoid receptor; Crebbp (show CREBBP ELISA Kits) = CREB binding protein (show CREBBP ELISA Kits))

  6. Data suggest that steroid receptor (show ESR2 ELISA Kits) coactivators (NCOA1 (show NCOA1 ELISA Kits), NCOA2 (show NCOA2 ELISA Kits), NCOA3) are over-expressed in a number of hormone-dependent cancers where they promote tumor growth, invasion, metastasis, and chemo-resistance; with their multiple roles in cancer, steroid receptor (show ESR2 ELISA Kits) coactivators are promising targets for development of antineoplastic agents that can interfere with their function. [REVIEW]

  7. Here, we reported the novel finding that depletion of SRC-3 enhanced sensitivity of breast and lung cancer cells to HDAC (show HDAC3 ELISA Kits) inhibitors (SAHA and romidepsin). In contrast, overexpression of SRC-3 decreased SAHA-induced cancer cell apoptosis. Furthermore, we found that SRC-3 inhibitor bufalin increased cancer cell apoptosis induced by HDAC (show HDAC3 ELISA Kits) inhibitors. The combination of bufalin and SAHA was particular efficient in attenuating

  8. Altered expression of AIB1 may play a role in adenomyosis development and treatment outcome with levonorgestrel-releasing intrauterine system.

  9. The oncogenic transcription factor AIB1 has a novel role in the regulation of polyribosome recruitment and formation of the translational complex. Combinatorial therapies targeting IGF signaling and mRNA translation in AIB1 expressing breast cancers may have clinical benefit and warrants further investigation

  10. Total SRC3 is selectively found at enhancer regions.

Mouse (Murine) Nuclear Receptor Coactivator 3 (NCOA3) interaction partners

  1. findings show that SRC-3 contributes to host defense against enteric bacteria, at least in part via upregulating CXCL2 (show CXCL2 ELISA Kits) expression to recruit neutrophils

  2. Findings indicate that the Gata6 (show GATA6 ELISA Kits) promoter is activated by Esrrb (show ESRRB ELISA Kits) in association with Ncoa3, and Dax1 (show NR0B1 ELISA Kits) inhibited activities of Esrrb (show ESRRB ELISA Kits) and Ncoa3, resulting maintenance of the undifferentiated status of embryonic stem (ES) cells.

  3. SRC-1 (show NCOA1 ELISA Kits)/3 are required for cardiomyocyte proliferation and differentiation at earlier developmental stages, and their dysfunction causes NCC (show SLC12A3 ELISA Kits)-like abnormalities in the hearts of newborn and adult mice.

  4. AIB1 promotes gastric cancer cell proliferation, survival and invasiveness through modulating major signaling pathways such as ErbB (show EGFR ELISA Kits) and Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathways. Findings suggest that AIB1 plays an important role in the pathogenesis of gastric cancer.

  5. SRC-3 is a target for inhibiting aggressive prostate cancer containing neuroendocrine tumor cells.

  6. Impaired hematopoiesis and delayed thrombopoietic recovery following sublethal irradiation in SRC3 knockout mice.

  7. The p/CIP gene regulatory network identifies various feed-forward modules including one in which p/CIP activates members of the extended pluripotency network, demonstrating that p/CIP is a component of this extended network.

  8. Loss of SRC3 also shows sex differences in anxiety and exploratory behaviors.

  9. IRS1 (show IRS1 ELISA Kits) levels are significantly increased in mouse cell lines representing fat and muscle lineages with p/CIP and SRC-1 (show NCOA1 ELISA Kits) deletions and in white adipose tissue and skeletal muscle of knockout mice.

  10. Data show that knockdown of nuclear receptor coactivator 3 (Ncoa3) not only compromises the expression of pluripotency markers but also impairs in vitro and in vivo differentiation potential of embryonic stem cells.

Nuclear Receptor Coactivator 3 (NCOA3) Antigen Profile

Antigen Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

Alternative names and synonyms associated with Nuclear Receptor Coactivator 3 (NCOA3)

  • nuclear receptor coactivator 3 (NCOA3) Elisa Kit
  • nuclear receptor coactivator 3 (Ncoa3) Elisa Kit
  • nuclear receptor coactivator 3 (ncoa3) Elisa Kit
  • 2010305B15Rik Elisa Kit
  • actr Elisa Kit
  • aib-1 Elisa Kit
  • aib1 Elisa Kit
  • AW321064 Elisa Kit
  • bHLHe42 Elisa Kit
  • cagh16 Elisa Kit
  • ctg26 Elisa Kit
  • kat13b Elisa Kit
  • NCOA3 Elisa Kit
  • p/Cip Elisa Kit
  • pcip Elisa Kit
  • rac3 Elisa Kit
  • src-3 Elisa Kit
  • src3 Elisa Kit
  • tnrc14 Elisa Kit
  • tnrc16 Elisa Kit
  • tram-1 Elisa Kit
  • Tram1 Elisa Kit
  • xSRC-3 Elisa Kit

Protein level used designations for NCOA3

nuclear receptor coactivator 3 , CBP-interacting protein , amplified in breast cancer 1 protein , class E basic helix-loop-helix protein 42 , receptor-associated coactivator 3 , steroid receptor coactivator protein 3 , thyroid hormone receptor activator molecule 1 , steroid receptor coactivator 3 , AIB-1 , NCoA-3 , RAC-3 , SRC-3 , amplified in breast cancer-1 protein homolog , retinoid X receptor-interacting coactivator xSRC-3

705431 Macaca mulatta
8202 Homo sapiens
100135659 Sus scrofa
17979 Mus musculus
485915 Canis lupus familiaris
523707 Bos taurus
84584 Rattus norvegicus
398021 Xenopus laevis
419208 Gallus gallus
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