Browse our anti-PPARGC1A (PPARGC1A) Antibodies

Full name:
anti-Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha Antibodies (PPARGC1A)
On www.antibodies-online.com are 0 Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) Antibodies from different suppliers available. Additionally we are shipping PPARGC1A Kits (2) and many more products for this protein. A total of 2 PPARGC1A products are currently listed.
Synonyms:
A830037N07Rik, AVPGC-1ALPHA, ENSMUSG00000079510, Gm11133, LEM6, PGC-1, PGC-1(alpha), Pgc-1alpha, PGC-1v, PGC1, PGC1A, Pgco1, Ppargc1, PPARGC1A
list all antibodies Gene Name GeneID UniProt
Anti-Mouse PPARGC1A PPARGC1A 19017 O70343
Anti-Human PPARGC1A PPARGC1A 10891 Q9UBK2
Anti-Rat PPARGC1A PPARGC1A 83516 Q9QYK2

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More Antibodies against PPARGC1A Interaction Partners

Mouse (Murine) Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) interaction partners

  1. Study demonstrates a novel role for peroxisome proliferator-activated receptor gamma (show PPARG Antibodies) coactivator-1alpha (PGC-1alpha) in nucleus accumbens (NAc (show NLRP1 Antibodies)) in cocaine action. PGC-1alpha is enhanced in NAc (show NLRP1 Antibodies) dopamine D1-medium spiny neurons, specifically after cocaine exposure. These data are consistent with increased active methylation and early growth response 3 (show EGR3 Antibodies) binding at the PGC-1alpha promoter.

  2. These data reveal a new role for muscle PGC-1alpha in regulating the physiological adaptation to long-term LCHF diet administration.

  3. These results demonstrate a central role of skeletal muscle PGC-1alpha in the transcriptional regulation of systemic ketolytic capacity.

  4. Our results indicate that prolonged Htr2b (show HTR2B Antibodies) activation in murine beta-cells decreases glucose-stimulated insulin (show INS Antibodies) secretion and mitochondrial activity by mechanisms likely dependent on enhanced PGC1a/PPARygexpression.

  5. PGC-1alpha expression in cardiomyocytes is regulated by interleukin-6 (show IL6 Antibodies) and is down-regulated in animals fed a high-fat diet.

  6. the data strengthen our previous findings that NT-PGC-1alpha regulates mitochondrial genes involved in thermogenesis and oxidative metabolism in brown and white adipocytes and further suggest that NT-PGC-1alpha regulates a broad spectrum of genes to meet cellular needs for adaptive thermogenesis.

  7. role of PGC-1alpha in renal mitochondrial biogenesis indicates that activation of PGC-1alpha in the context of renal disorders could be a valid therapeutic strategy to ameliorate renal mitochondrial dysfunction

  8. Results delineate a cross talk between a central pathway controlling metabolic regulation and cell adhesion, and identify PGC-1alpha as a molecular link between these two major cellular networks.

  9. Data suggest NT-Pgc-1alpha (alternative splicing isoform of nuclear protein Pgc-1alpha) is located in mitochondrial matrix in brown adipocytes, specifically enriched at D-loop region of mitochondrial DNA at promoter region of Lrpprc (leucine-rich PPR-motif containing (show LRPPRC Antibodies) protein); expression of NT-Pgc-1alpha (rather than Pgc-1alpha) in brown adipocytes appears to induce expression of electron transport chain complex proteins.

  10. Data suggest that PGC-1alpha and -1beta expression are not required for training-induced exercise performance, highlighting the contribution of PGC-1-independent mechanisms.

Pig (Porcine) Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) interaction partners

  1. Transcription of the gene was detected in adipose, muscle, kidney, liver, brain, heart and adrenal gland tissues, which is in agreement with the function of PPARGC1A in adaptive thermogenesis.

  2. The purpose of this study was to screen for new single nucleotide polymorphisms in exon 8 of the porcine PPARGC1A gene and to test their possible association with production traits.

  3. impact of PPARGC1A on energy and lipid metabolism in vivo, through several downstream target genes

  4. The *2690T>C and *2864T>C polymorphisms in PPARGC1A can be used as genetic markers for selection toward improved meat quality.

  5. The c.-2894G>A polymorphism in the 5' upstream region of the porcine PPARGC1A gene can be used as a meaningful molecular marker for simultaneous improvement of lean meat production and quality traits.

  6. PPARGC1A may play a key role in down-regulating lipid deposition, and the SNPs with differential genotype distribution among three breeds may be related to gene expression and fat deposition.

  7. Polymorphisms in PPARGC1A and CAPNS1 (show CAPNS1 Antibodies) genes may affect meat quality traits.

Human Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) interaction partners

  1. Supplementation of omega-3 fatty acids in combination with vitamin E may have beneficial effects on coronary artery disease patients by increasing gene expression of SIRT1 (show SIRT1 Antibodies) and PGC1alpha and improving oxidative stress and inflammation in these patients.

  2. Results delineate a cross talk between a central pathway controlling metabolic regulation and cell adhesion, and identify PGC-1alpha as a molecular link between these two major cellular networks.

  3. Haplotype-based interaction between the PPARGC1A and UCP1 (show UCP1 Antibodies) genes is associated with impaired fasting glucose (IFG (show IFNG Antibodies)) or type 2 diabetes mellitus (T2DM) among the residents of Henan province, China. Individuals with the haplotype AAG (show MPG Antibodies) (PPARGC1A gene) and CTCG (UCP1 (show UCP1 Antibodies) gene) have increased susceptibility to IFG (show IFNG Antibodies) or T2DM, while those with haplotype AAG (show MPG Antibodies) (PPARGC1A gene) and CTCA (UCP1 (show UCP1 Antibodies) gene) have a lower risk of IFG (show IFNG Antibodies) or T2DM.

  4. The miR (show MLXIP Antibodies)-130b-3p down-regulates PGC-1alpha expression in placental trophoblasts, and inhibition of miR (show MLXIP Antibodies)-130b-3p appears to improve mitochondrial biogenesis signaling and protect placental trophoblast cells from oxidative stress.

  5. the RAR-related orphan receptor-a (show RORA Antibodies) gene (RORA (show RORA Antibodies)) and the Peroxisome Proliferator-Activated Receptor Gamma (show PPARG Antibodies), Coactivator 1 Alpha gene (PPARGC1A or PGC-1alpha) were significantly associated with the Li response. Our results suggest genetic associations between Li response and these two close biological partners: PPARGC1A and RORA (show RORA Antibodies) involved in circadian rhythms and bioenergetics processes in Li response

  6. Schizophrenia involves a disruption in PGC-1alpha and/or NRF-1 (show NFE2L1 Antibodies)-associated transcriptional programs in the cortex.

  7. In molecular dynamics simulations, PGC1alpha induced correlated atomic motion throughout the entire LRH-1 (show NR5A2 Antibodies) activation function surface.

  8. PPARGC1A promoter methylation and mitochondrial content were found to be potential biomarkers for the prediction of metabolic risk in women with polycystic ovary syndrome.

  9. that PGC1alpha activates an oestrogen-related receptor alpha (ERRalpha (show ESRRA Antibodies))-dependent transcriptional program to elicit a catabolic state and metastasis suppression

  10. Review the most recent progress on PGC-1alpha and discuss its regulatory network in major glucose metabolic tissues such as the liver, skeletal muscle, pancreas and kidney. The significant associations between PGC-1alpha polymorphisms and type 2 diabetes mellitus are also discussed. Review.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) interaction partners

  1. PPARGC1A single nucleotide polymorphisms associated with milk fatty acids in a Chinese Holstein cattle.

  2. The PPARGC1A synonymous mutation c.396G>A significantly associated with body weight and average daily gain in Nanyang cattle at the adult age.

  3. PPARGC1A genotypes had a significant effect on lengths of calving interval and calving to conception interval, and the T allele was demonstrated to have an unfavourable effect on these traits.

  4. NO/protein kinase (show CDK7 Antibodies) G (PKG (show PRKG1 Antibodies))-dependent downregulation of PGC-1 alpha and the ROS (show ROS1 Antibodies) detoxification system in endothelial cells are mediated by the PI3K/Akt (show AKT1 Antibodies) signaling

  5. The effects of dietary fat components on the expression of PPAR-gamma (show PPARG Antibodies) AND PPAR-gamma coactivator 1 in cultured bovine preadipocytes are reported.

  6. genetic analysis of bovine PPARGC1A

  7. PPARGC1A was associated with a significant increase in milk protein (show CSN2 Antibodies) percentage in contrast to association results previously reported for the German Holstein population

PPARGC1A Antigen Profile

Antigen Summary

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Alternative names and synonyms associated with PPARGC1A

  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PPARGC1A) antibody
  • peroxisome proliferative activated receptor, gamma, coactivator 1 alpha (Ppargc1a) antibody
  • peroxisome proliferator activated receptor gamma, coactivator 1 alpha (PPARGC-1) antibody
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (Ppargc1a) antibody
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (ppargc1a) antibody
  • A830037N07Rik antibody
  • AVPGC-1ALPHA antibody
  • ENSMUSG00000079510 antibody
  • Gm11133 antibody
  • LEM6 antibody
  • PGC-1 antibody
  • PGC-1(alpha) antibody
  • Pgc-1alpha antibody
  • PGC-1v antibody
  • PGC1 antibody
  • PGC1A antibody
  • Pgco1 antibody
  • Ppargc1 antibody
  • PPARGC1A antibody

Protein level used designations for PPARGC1A

peroxisome proliferator-activated receptor gamma, coactivator 1 alpha , PPAR-gamma coactivator , peroxisome proliferator activated receptor gamma coactivator-1 , PGC-1-alpha , PPAR Gamma Coactivator-1 , PPAR gamma coactivator variant form , PPAR-gamma coactivator 1-alpha , PPARGC-1-alpha , Pgc-1alphaa , peroxisome proliferator-activated receptor gamma coactivator 1-alpha , L-PGC-1alpha , ligand effect modulator-6 , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4 , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5 , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT , peroxisome proliferative activated receptor, gamma, coactivator 1 , peroxisome proliferator activated receptor gamma coactivator 1 alpha , PGC-1alpha , peroxisome proliferative activated receptor gamma coactivator 1 , peroxisome proliferative activated receptor, gamma, coactivator 1 alpha , proliferator-activated receptor gamma coactivator 1 alpha , peroxisome proliferative activated receptor, gamma, coactivator 1, alpha , peroxisome-proliferator-activated receptor-gamma co-activator-1

GENE ID SPECIES
443270 Ovis aries
19017 Mus musculus
397013 Sus scrofa
10891 Homo sapiens
479127 Canis lupus familiaris
338446 Bos taurus
83516 Rattus norvegicus
100462892 Xenopus laevis
422815 Gallus gallus
100349219 Oryctolagus cuniculus
100721512 Cavia porcellus
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