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Browse our anti-RNF4 (RNF4) Antibodies

Full name:
anti-Ring Finger Protein 4 Antibodies (RNF4)
On are 17 Ring Finger Protein 4 (RNF4) Antibodies from 10 different suppliers available. Additionally we are shipping RNF4 Kits (19) and RNF4 Proteins (8) and many more products for this protein. A total of 46 RNF4 products are currently listed.
AU018689, Gtrgeo8, SLX5, SNURF
list all antibodies Gene Name GeneID UniProt
RNF4 6047 P78317
RNF4 19822 Q9QZS2
Anti-Rat RNF4 RNF4 29274 O88846

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Most Popular Reactivities for anti-RNF4 (RNF4) Antibodies

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anti-Human RNF4 Antibodies:

anti-Mouse (Murine) RNF4 Antibodies:

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Top referenced anti-RNF4 Antibodies

  1. Human Polyclonal RNF4 Primary Antibody for EIA, WB - ABIN954575 : Hu, Rodrigues, Tao, Baker, Miraglia, Orth, Lyons, Schultz, Wu: Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 4 references for ABIN954575

  2. Human Polyclonal RNF4 Primary Antibody for WB - ABIN1537658 : Wang, Sang, Ren, Liu, Liu, Zhang, Wang, Wang, Orian, Yang, Yi: SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation. in Protein & cell 2015 (PubMed)

More Antibodies against RNF4 Interaction Partners

Human Ring Finger Protein 4 (RNF4) interaction partners

  1. These results point to an important role of the affinity between RNF4 and its cognate RAD6B (show UBE2B Antibodies) or UBCH5B (show UBE2D2 Antibodies) in governing the multiplicity of substrate ubiquitination.

  2. the opposing activities of RNF4 and ataxin-3 (show ATXN3 Antibodies) consolidate robust MDC1 (show MDC1 Antibodies)-dependent signaling and repair ofDNA double-strand break.

  3. Combined effect of dynamic recruitment of RNF4 to KAP1 regulates the relative occupancy of 53BP1 and BRCA1 at double-strand break sites to direct DNA repair in a cell cycle-dependent manner.

  4. c-Myc (show MYC Antibodies) is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1 (show PIAS1 Antibodies), SENP7 (show SENP7 Antibodies) and RNF4

  5. Data show that RNF4 is a SUMO-targeted ubiquitin ligase that targets TRF2 (show TERF2 Antibodies) for ubiquitination.

  6. novel insight into cross-talk between ubiquitin and SUMO and uncover USP11 (show USP11 Antibodies) and RNF4 as a balanced SUMO-targeted ubiquitin ligase/protease pair with a role in the DDR (show DDR1 Antibodies).

  7. RNF4 negatively regulates NF-kappaB (show NFKB1 Antibodies) signaling by down-regulating TAB2 (show TAB2 Antibodies)

  8. RNF4 enhances Ube2E1 (show UBE2E1 Antibodies) self-ubiquitination.

  9. NMR spectroscopy and biochemical characterization reveal how RNF4 manipulates the conformation of the SUMO chain, thereby facilitating optimal delivery of the distal SUMO domain for ubiquitin transfer.

  10. RecQ-like helicase BLM subcellular localization is regulated by SUMO-targeted ubiquitin ligase RNF4 in response to DNA damage, presumably to prevent illegitimate recombination events.

Mouse (Murine) Ring Finger Protein 4 (RNF4) interaction partners

  1. These findings suggest that the UBC9/PML/RNF4 axis plays a critical role as an important SUMO pathway in cardiac fibrosis. Modulating the protein levels of the pathway provides an attractive therapeutic target for the treatment of cardiac fibrosis and heart failure.

  2. This paper identifies a nucleosome-targeting motif within the RNF4 RING domain that can bind DNA and thereby enables RNF4 to selectively ubiquitinate nucleosomal histones.

  3. fork collapse in Atr (show ATR Antibodies)-deleted cells is mediated through the combined effects the sumo targeted E3-ubiquitin ligase RNF4 and activation of the AURKA (show AURKA Antibodies)-PLK1 (show PLK1 Antibodies) pathway

  4. Rnf4 controls protein localization at DNA damage sites by integrating SUMOylation and ubiquitylation events.

  5. SUMO interacting motif is dispensable for PML (show PML Antibodies) SUMOylation and interaction with RNF4 but is required for efficient PML (show PML Antibodies) ubiquitination, recruitment of proteasome components within NBs (show NLRP2 Antibodies) and proteasome-dependent degradation of PML (show PML Antibodies) in response to AsO

  6. Rnf4 deficiency is embryonic lethal with higher levels of methylation in genomic DNA. Mechanistic studies show that RNF4 interacts with and requires the base excision repair enzymes TDG (show TDG Antibodies) and APE1 (show APEX1 Antibodies) for active demethylation.

  7. GC-rich (show RELB Antibodies) elements flanking the transcription start site govern activation

  8. 1.6- and 3.0-kb transcripts originate from the same promoter, encode for the same protein and differ in the 3' UTR (show UTS2R Antibodies).

  9. RNF4 is a negative regulator of TRPS1 (show TRPS1 Antibodies) activity

  10. results suggest a role for small nuclear ring finger protein(SNURF/RNF4) in fetal germ cell development as well as in oocyte and granulosa cell maturation in an estrogen- and gonadotropin-regulated fashion

RNF4 Antigen Profile

Antigen Summary

The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.

Alternative names and synonyms associated with RNF4

  • ring finger protein 4 (RNF4) antibody
  • ring finger protein 4 (Rnf4) antibody
  • ring finger protein 4 (LOC100348357) antibody
  • AU018689 antibody
  • Gtrgeo8 antibody
  • SLX5 antibody
  • SNURF antibody

Protein level used designations for RNF4

E3 ubiquitin ligase RNF4 , E3 ubiquitin-protein ligase RNF4 , small nuclear RING finger protein , gene trap ROSA b-geo 8 , SNURF , small nuclear ring finger protein , RING finger protein 4

6047 Homo sapiens
19822 Mus musculus
29274 Rattus norvegicus
100348357 Oryctolagus cuniculus
100735750 Cavia porcellus
692189 Sus scrofa
617018 Bos taurus
101110510 Ovis aries
610552 Canis lupus familiaris
422886 Gallus gallus
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