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Browse our anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) Antibodies

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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Antibodies (SMARCA4)
On www.antibodies-online.com are 99 SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) Antibodies from 24 different suppliers available. Additionally we are shipping SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Proteins (6) and SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Kits (1) and many more products for this protein. A total of 108 SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 products are currently listed.
Synonyms:
b2b692Clo, BAF190, BAF190A, brg-1, Brg1, HP1-BP72, hSNF2b, MRD16, RTPS2, SMARCA4, SNF2, SNF2beta, SNF2L4, SNF2LB, SW1/SNF, SWI2
list all antibodies Gene Name GeneID UniProt
SMARCA4 6597 P51532
SMARCA4 171379  
SMARCA4 20586 Q3TKT4

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All available anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Antibodies

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Top referenced anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Antibodies

  1. Human Monoclonal SMARCA4 Primary Antibody for WB - ABIN343708 : Griffin, Brennan, Magnuson: The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development. in Development (Cambridge, England) 2008 (PubMed)
    Show all 4 references for ABIN343708

  2. Human Monoclonal SMARCA4 Primary Antibody for IHC (p), WB - ABIN614772 : Ooi, Belyaev, Miyake, Wood, Buckley: BRG1 chromatin remodeling activity is required for efficient chromatin binding by repressor element 1-silencing transcription factor (REST) and facilitates REST-mediated repression. in The Journal of biological chemistry 2006 (PubMed)
    Show all 4 references for ABIN614772

  3. Human Polyclonal SMARCA4 Primary Antibody for ChIP, ICC - ABIN4285245 : Miyamoto, Pasque, Jullien, Gurdon: Nuclear actin polymerization is required for transcriptional reprogramming of Oct4 by oocytes. in Genes & development 2011 (PubMed)
    Show all 4 references for ABIN4285245

  4. Human Polyclonal SMARCA4 Primary Antibody for WB - ABIN871762 : Park, Venteicher, Hong, Choi, Jun, Shkreli, Chang, Meng, Cheung, Ji, McLaughlin, Veenstra, Nusse, McCrea, Artandi: Telomerase modulates Wnt signalling by association with target gene chromatin. in Nature 2009 (PubMed)
    Show all 3 references for ABIN871762

  5. Human Monoclonal SMARCA4 Primary Antibody for ICC, IF - ABIN2668498 : de la Serna, Ohkawa, Higashi, Dutta, Osias, Kommajosyula, Tachibana, Imbalzano: The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Interaction Partners

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) interaction partners

  1. BRG1/BRM (show SMARCA2 Antibodies) and c-MYC (show MYC Antibodies) have an antagonistic relationship regulating the expression of cardiac conduction genes that maintain contractility, which is reminiscent of their antagonistic roles as a tumor suppressor and oncogene (show RAB1A Antibodies) in cancer.

  2. Small-cell carcinoma of the ovary of hypercalcemic type is characterized by deleterious germline or somatic mutations in SMARCA4.

  3. SMARCA4 and SMARCA2 (show SMARCA2 Antibodies) deficiency is observed in 5.1% and 4.8% of non-small cell lung cancer

  4. BRG1 is involved in the progression and metastasis of breast cancer and can serve as a novel biomarker predictive of distant metastasis and patient outcomes.

  5. Results provide evidence that BRG1 and SMARCAL1 (show SMARCAL1 Antibodies) regulate each other. BRG1 binds to the SMARCAL1 (show SMARCAL1 Antibodies) promoter, while SMARCAL1 (show SMARCAL1 Antibodies) binds to the brg1 promoter. During DNA damage, the occupancy of SMARCAL1 (show SMARCAL1 Antibodies) on the brg1 promoter increases coinciding with an increase in BRG1 occupancy on the SMARCAL1 (show SMARCAL1 Antibodies) promoter, leading to increased brg1 and SMARCAL1 (show SMARCAL1 Antibodies) transcripts respectively.

  6. The CRISPR/Cas9 system may control a pro-oncogenic splicing process through the exclusion of EDA (show EDA Antibodies) exon from the FN gene, leading to inhibition of motility, invasion and proliferation of cancer cells.

  7. Knock down of BRG1 in resistant cells restored sensitivity to retinoic acid-mediated differentiation, from early gene expression to terminal functional capacity.

  8. Data indicate that SMARCA4 protein inactivation is the main cause of small cell carcinoma of the ovary, hypercalcemic type (SCCOHT).

  9. our data suggest that concomitant loss of SMARCA2 (show SMARCA2 Antibodies) and SMARCA4 is another hallmark of small cell carcinoma of the ovary, hypercalcemic type-a finding that offers new opportunities for therapeutic interventions.

  10. Activation of DPF3a upon hypertrophic stimuli in cardiac hypertrophy switches cardiac fetal gene expression from being silenced by HEY to being activated by BRG1.

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) interaction partners

  1. BRG1/BRM (show SMARCA2 Antibodies) and c-MYC (show MYC Antibodies) have an antagonistic relationship regulating the expression of cardiac conduction genes that maintain contractility, which is reminiscent of their antagonistic roles as a tumor suppressor and oncogene (show RAB1A Antibodies) in cancer.

  2. Results provide insights into the mechanisms by which Brg1 functions, which is in part via the p53 (show TP53 Antibodies) program, to constrain gene expression and facilitate rapid embryonic growth.

  3. Brg1 promotes neurogenic radial glial progenitor cell specification but is dispensable for neuronal differentiation

  4. SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) chromatin remodeler subunits Brg1 and Brm (show SMARCA2 Antibodies) are expressed differentially during drug-induced liver injury and regeneration in a mouse model.

  5. these findings described a role for BRG1 and BRM (show SMARCA2 Antibodies) in mitochondrial quality control, by regulating mitochondrial number, mitophagy, and mitochondrial dynamics not previously recognized in the adult cardiomyocyte

  6. show that epigenetic chromatin remodeling (via a Brg1 and p53 (show TP53 Antibodies)/p21 (show D4S234E Antibodies)-dependent process) determines the aNSCs and progenitor maintenance and responsiveness of neurogenesis.

  7. The stress-induced Brg1-G9a (show EHMT2 Antibodies)/GLP (show GOLGA6A Antibodies)-Dnmt3 interactions and sequence of repressive chromatin assembly on Myh6 (show MYH6 Antibodies) promoter illustrates a molecular mechanism by which the heart epigenetically responds to environmental signals.

  8. MITF (show MITF Antibodies) interacts with BRG1 to promote GATA4 (show GATA4 Antibodies) expression in cardiac hypertrophy.

  9. SMARCA4 is involved in the TOP1 (show TOP1 Antibodies) recruitment to general chromatin, which suppresses transcription-associated genomic instability.

  10. the role of SMARCA4 and the two SWI/SNF subunits SMARCD2/BAF60B and DPF2/BAF45D in leukaemia, was investigated.

SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4)

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4) antibody
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (Smarca4) antibody
  • b2b692Clo antibody
  • BAF190 antibody
  • BAF190A antibody
  • brg-1 antibody
  • Brg1 antibody
  • HP1-BP72 antibody
  • hSNF2b antibody
  • MRD16 antibody
  • RTPS2 antibody
  • SMARCA4 antibody
  • SNF2 antibody
  • SNF2beta antibody
  • SNF2L4 antibody
  • SNF2LB antibody
  • SW1/SNF antibody
  • SWI2 antibody

Protein level used designations for SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 , transcription activator BRG1-like , ATP-dependent helicase SMARCA4 , BRG1-associated factor 190A , BRM/SWI2-related gene 1 , SNF2-beta , SNF2-like 4 , brahma protein-like 1 , global transcription activator homologous sequence , homeotic gene regulator , mitotic growth and transcription activator , nuclear protein GRB1 , protein BRG-1 , protein brahma homolog 1 , sucrose nonfermenting-like 4 , transcription activator BRG1 , BAF190A , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 , SWI/SNF related transcriptional activator , WI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

GENE ID SPECIES
455720 Pan troglodytes
476710 Canis lupus familiaris
100415454 Callithrix jacchus
100446301 Pongo abelii
100464834 Ailuropoda melanoleuca
6597 Homo sapiens
171379 Rattus norvegicus
20586 Mus musculus
414274 Bos taurus
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