Browse our SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) ELISA Kits

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SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 ELISA Kits (SMARCA4)
On www.antibodies-online.com are 1 SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) ELISA Kits from 1 different suppliers available. Additionally we are shipping SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Antibodies (100) and SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Proteins (7) and many more products for this protein. A total of 109 SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 products are currently listed.
Synonyms:
b2b692Clo, BAF190, BAF190A, brg-1, Brg1, HP1-BP72, hSNF2b, MRD16, RTPS2, SMARCA4, SNF2, SNF2beta, SNF2L4, SNF2LB, SW1/SNF, SWI2
list all ELISA KIts Gene Name GeneID UniProt
SMARCA4 6597 P51532
Rat SMARCA4 SMARCA4 171379  
Mouse SMARCA4 SMARCA4 20586 Q3TKT4

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SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) ELISA Kits by Reactivity

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More ELISA Kits for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 Interaction Partners

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) interaction partners

  1. BRG1 was significantly increased in hepatocellular carcinoma. Overexpression of BRG1 increases cell growth and invasiveness in HCC (show FAM126A ELISA Kits).

  2. Case Report: SMARCA4 nonsense/frameshift mutations responsible for concomitant Coffin-Siris syndrome, microphthalmia and small-cell carcinoma of the ovary hypercalcaemic type.

  3. i-motif structures in long cytosine-rich sequences found upstream of the promoter region of the SMARCA4 gene

  4. Brg1 coordinates a genetic and epigenetic network that regulates the transcriptional program underlying the Shh (show SHH ELISA Kits)-type medulloblastoma development.

  5. whole-genome transcriptome analysis revealed that BRG1 controls the expression of key elements of oncogenic pathways such as PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) and BCL2 (show BCL2 ELISA Kits), which offers a promising new combination therapy for high-risk Neuroblastoma (show ARHGEF16 ELISA Kits) (NB).

  6. A breakdown in a BRCA/FANCD2 (show FANCD2 ELISA Kits)/BRG1/SNF (show SNRPA ELISA Kits)-DeltaNP63-mediated DNA repair and differentiation maintenance process in mammary epithelial cells may contribute to sporadic breast cancer development.

  7. both ABCB1 (show ABCB1 ELISA Kits) upregulation and doxorubicin resistance caused by SMARCB1 (show SMARCB1 ELISA Kits) loss were dependent on the function of SMARCA4, a catalytic subunit of the SWI (show SMARCA1 ELISA Kits)/SNF (show SNRPA ELISA Kits) complex.

  8. BRG1 participates in gene repression by interacting with H1.2 (show HIST1H1C ELISA Kits), facilitating its deposition and stabilizing nucleosome positioning around the transcription start site.

  9. Cdx (show CDX1 ELISA Kits) members interact with the SWI (show SMARCA1 ELISA Kits)-SNF (show SNRPA ELISA Kits) complex and make direct contact with Brg1, a catalytic member of SWI (show SMARCA1 ELISA Kits)-SNF (show SNRPA ELISA Kits). Both Cdx2 (show CDX2 ELISA Kits) and Brg1 co-occupy a number of Cdx (show CDX1 ELISA Kits) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 (show CDX2 ELISA Kits) and Brg1 occupancy occurs coincident with chromatin remodeling at some of these loci.

  10. BRG1/BRM (show SMARCA2 ELISA Kits) and c-MYC (show MYC ELISA Kits) have an antagonistic relationship regulating the expression of cardiac conduction genes that maintain contractility, which is reminiscent of their antagonistic roles as a tumor suppressor and oncogene (show RAB1A ELISA Kits) in cancer.

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) interaction partners

  1. Data demonstrate that Brg1 plays an essential role in development and homeostasis, including morphogenesis, stem cell differentiation and cell survival in the duodenum.

  2. Point mutations in SMARCA4 (also known as BRG1) mapping to the ATPase (show DNAH8 ELISA Kits) domain cause loss of direct binding between BAF (show BANF1 ELISA Kits) and PRC1 (show PRC1 ELISA Kits).

  3. BRG1 promotes transcription of endothelial Mrtfa and Mrtfb, which elevates expression of SRF and SRF target genes that establish embryonic capillary integrity.

  4. RB is necessary for the recruitment of the BRG1 ATPase (show DNAH8 ELISA Kits) to DNA double-strand breaks, which stimulates DNA end resection and homologous recombination

  5. Cdx (show CDX1 ELISA Kits) members interact with the SWI (show SMARCA1 ELISA Kits)-SNF (show SNRPA ELISA Kits) complex and make direct contact with Brg1, a catalytic member of SWI (show SMARCA1 ELISA Kits)-SNF (show SNRPA ELISA Kits). Both Cdx2 (show CDX2 ELISA Kits) and Brg1 co-occupy a number of Cdx (show CDX1 ELISA Kits) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 (show CDX2 ELISA Kits) and Brg1 occupancy occurs coincident with chromatin remodeling at some of these loci.

  6. BRG1/BRM (show SMARCA2 ELISA Kits) and c-MYC (show MYC ELISA Kits) have an antagonistic relationship regulating the expression of cardiac conduction genes that maintain contractility, which is reminiscent of their antagonistic roles as a tumor suppressor and oncogene (show RAB1A ELISA Kits) in cancer.

  7. Results provide insights into the mechanisms by which Brg1 functions, which is in part via the p53 (show TP53 ELISA Kits) program, to constrain gene expression and facilitate rapid embryonic growth.

  8. Brg1 promotes neurogenic radial glial progenitor cell specification but is dispensable for neuronal differentiation

  9. SWI (show SMARCA1 ELISA Kits)/SNF (show SNRPA ELISA Kits) chromatin remodeler subunits Brg1 and Brm (show SMARCA2 ELISA Kits) are expressed differentially during drug-induced liver injury and regeneration in a mouse model.

  10. these findings described a role for BRG1 and BRM (show SMARCA2 ELISA Kits) in mitochondrial quality control, by regulating mitochondrial number, mitophagy, and mitochondrial dynamics not previously recognized in the adult cardiomyocyte

SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4)

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (SMARCA4) Elisa Kit
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (Smarca4) Elisa Kit
  • b2b692Clo Elisa Kit
  • BAF190 Elisa Kit
  • BAF190A Elisa Kit
  • brg-1 Elisa Kit
  • Brg1 Elisa Kit
  • HP1-BP72 Elisa Kit
  • hSNF2b Elisa Kit
  • MRD16 Elisa Kit
  • RTPS2 Elisa Kit
  • SMARCA4 Elisa Kit
  • SNF2 Elisa Kit
  • SNF2beta Elisa Kit
  • SNF2L4 Elisa Kit
  • SNF2LB Elisa Kit
  • SW1/SNF Elisa Kit
  • SWI2 Elisa Kit

Protein level used designations for SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 , transcription activator BRG1-like , ATP-dependent helicase SMARCA4 , BRG1-associated factor 190A , BRM/SWI2-related gene 1 , SNF2-beta , SNF2-like 4 , brahma protein-like 1 , global transcription activator homologous sequence , homeotic gene regulator , mitotic growth and transcription activator , nuclear protein GRB1 , protein BRG-1 , protein brahma homolog 1 , sucrose nonfermenting-like 4 , transcription activator BRG1 , BAF190A , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 , SWI/SNF related transcriptional activator , WI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

GENE ID SPECIES
455720 Pan troglodytes
476710 Canis lupus familiaris
100415454 Callithrix jacchus
100446301 Pongo abelii
100464834 Ailuropoda melanoleuca
6597 Homo sapiens
171379 Rattus norvegicus
20586 Mus musculus
414274 Bos taurus
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