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Human Polyclonal ZBTB17 Primary Antibody for IHC, IHC (p) - ABIN4334796
Chan, Lee, Li, Wang, Yang, Wu, Wu, Nakayama, Kang, Huang, Hung, Pandolfi, Lin: Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis. in Nature cell biology 2010
Miz1 is a newly identified ING4 (show ING4 Antibodies)-induced target gene which can drive prostate luminal epithelial cell differentiation.
The mechanism of inhibition of c-Myc (show MYC Antibodies) transcriptional activity by Miz-1 that binds c-Myc (show MYC Antibodies) while competing for binding with Max has been described.
This study used NMR to deduce the role of Miz-1 Zinc Fingers 1-4 in detecting the Miz-1 consensus sequence and preventing nonspecific DNA binding.
the silencing of Miz-1 expression inhibited cell proliferation and promoted apoptosis in vitro and reduced the migration ability in esophageal carcinoma cells.
This study presents the structure of the synthetic Miz-1 Zinc Finger 13 determined by 2D (1)H-(1)H NMR.
results indicate that Miz-1 may be directed in vivo to the novel motif sequences we have identified, where it can recruit its specific binding partners to control gene expression and ultimately regulate cell fate
MIZ-1 can promote the proliferation of breast cancer cells through Wnt (show WNT2 Antibodies) signaling.
We demonstrate that Arnt (show ARNT Antibodies) is an interaction partner for Miz-1, and that Arnt (show ARNT Antibodies) has a functional role in the regulation of CDKN2B (show CDKN2B Antibodies)
The functional interaction of both proteins becomes apparent at oncogenic expression levels of MYC (show MYC Antibodies) and association with MIZ-1 mediates both oncogenic functions of MYC (show MYC Antibodies) as well as tumor-suppressive responses to oncogenic levels of MYC (show MYC Antibodies).
The ZBTB17 polymorphism rs10927875 appears to play a role in the susceptibility of the Han Chinese population to dilated cardiomyopathy .
rather than via E-Box binding, cMyc (show MYC Antibodies) acts in the dorsal neural tube by interacting with another transcription factor, Miz1 (show PIAS2 Antibodies), to promote self-renewal. The finding that cMyc (show MYC Antibodies) operates in a non-canonical manner in the premigratory neural crest highlights the importance of examining its role at specific time points and in an in vivo context.
the Myc (show MYC Antibodies)/Miz1 (show PIAS2 Antibodies) interaction is a defining hallmark of Sonic Hedgehog (show SHH Antibodies) medulloblastomas development
Miz-1 regulates translation of Trp53 (show TP53 Antibodies) via ribosomal protein L22 (show RPL22 Antibodies) in cells undergoing V(D)J recombination.
Miz1 (show PIAS2 Antibodies) plays an essential role in myelin homeostasis of peripheral nerves.
The interaction of Nac1 (show NACC1 Antibodies) with Miz1 (show PIAS2 Antibodies) may thus be relevant to its mechanism of tumourigenesis in ovarian cancer.
Conditional knockout of the Miz1 (show PIAS2 Antibodies) POZ domain in luminal cells during pregnancy caused a lactation defect with a transient reduction of glandular tissue, reduced proliferation and attenuated differentiation.
Miz1 (show PIAS2 Antibodies) may link cell growth and ribosome biogenesis to the transcriptional regulation of vesicular transport and autophagy.
Miz1 (show PIAS2 Antibodies) as a novel regulator in the Hedgehog (show SHH Antibodies) protein signal pathway that plays an important role in mediating Smo-dependent oncogenic signaling.
data demonstrate in vivo that Mule suppresses Ras-mediated tumorigenesis by preventing an accumulation of c-Myc (show MYC Antibodies)/Miz1 (show PIAS2 Antibodies) complexes that mediates p21 (show D4S234E Antibodies) and p15 (show CDKN2B Antibodies) down-regulation
this study reports that the transcription factor Miz1 (show PIAS2 Antibodies) was required for terminating lipopolysaccharide (LPS (show TLR4 Antibodies))-induced inflammation.
This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18.
Myc-interacting Zn finger protein-1
, myc-interacting zinc finger protein 1
, zinc finger and BTB domain-containing protein 17
, zinc finger protein 151 (pHZ-67)
, zinc finger protein 60
, polyomavirus late initiator promoter-binding protein
, zinc finger protein 100
, zinc finger protein 151
, zinc finger protein Z13