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Miz1 is a newly identified ING4 (show ING4 ELISA Kits)-induced target gene which can drive prostate luminal epithelial cell differentiation.
strategy for the purification of tethered POZ domains that form forced heterodimers is described, and crystal structures of the heterodimeric POZ domains of Miz1/BCL6 (show BCL6 ELISA Kits) and of Miz1/NAC1 (show NACC1 ELISA Kits) are reported
The mechanism of inhibition of c-Myc (show MYC ELISA Kits) transcriptional activity by Miz-1 that binds c-Myc (show MYC ELISA Kits) while competing for binding with Max has been described.
This study used NMR to deduce the role of Miz-1 Zinc Fingers 1-4 in detecting the Miz-1 consensus sequence and preventing nonspecific DNA binding.
the silencing of Miz-1 expression inhibited cell proliferation and promoted apoptosis in vitro and reduced the migration ability in esophageal carcinoma cells.
This study presents the structure of the synthetic Miz-1 Zinc Finger 13 determined by 2D (1)H-(1)H NMR.
results indicate that Miz-1 may be directed in vivo to the novel motif sequences we have identified, where it can recruit its specific binding partners to control gene expression and ultimately regulate cell fate
the expression of SENP8 (show SENP8 ELISA Kits), SAE1 (show SAE1 ELISA Kits), PIAS1 (show PIAS1 ELISA Kits), PIAS2 (show PIAS2 ELISA Kits) and ZMIZ1 (show ZMIZ1 ELISA Kits) is deregulated in the majority of PTC (show F9 ELISA Kits) tissues, likely contributing to the PTC (show F9 ELISA Kits) phenotype.
UXT (show UXT ELISA Kits) is a binding protein of PIAS2 (show PIAS2 ELISA Kits), and interaction between PIAS2 (show PIAS2 ELISA Kits) and UXT (show UXT ELISA Kits) may be important for the transcriptional activation of AR.
MIZ-1 can promote the proliferation of breast cancer cells through Wnt (show WNT2 ELISA Kits) signaling.
the Myc (show MYC ELISA Kits)/Miz1 (show PIAS2 ELISA Kits) interaction is a defining hallmark of Sonic Hedgehog (show SHH ELISA Kits) medulloblastomas development
Miz-1 regulates translation of Trp53 (show TP53 ELISA Kits) via ribosomal protein L22 (show RPL22 ELISA Kits) in cells undergoing V(D)J recombination.
Miz1 (show PIAS2 ELISA Kits) plays an essential role in myelin homeostasis of peripheral nerves.
The interaction of Nac1 (show NACC1 ELISA Kits) with Miz1 (show PIAS2 ELISA Kits) may thus be relevant to its mechanism of tumourigenesis in ovarian cancer.
Conditional knockout of the Miz1 (show PIAS2 ELISA Kits) POZ domain in luminal cells during pregnancy caused a lactation defect with a transient reduction of glandular tissue, reduced proliferation and attenuated differentiation.
Miz1 (show PIAS2 ELISA Kits) may link cell growth and ribosome biogenesis to the transcriptional regulation of vesicular transport and autophagy.
Miz1 as a novel regulator in the Hedgehog protein signal pathway that plays an important role in mediating Smo-dependent oncogenic signaling.
data demonstrate in vivo that Mule suppresses Ras-mediated tumorigenesis by preventing an accumulation of c-Myc (show MYC ELISA Kits)/Miz1 (show PIAS2 ELISA Kits) complexes that mediates p21 and p15 (show CDKN2B ELISA Kits) down-regulation
this study reports that the transcription factor Miz1 (show PIAS2 ELISA Kits) was required for terminating lipopolysaccharide (LPS (show TLR4 ELISA Kits))-induced inflammation.
Our data demonstrate that Miz1 (show PIAS2 ELISA Kits)-mediated attenuation of cell cycle arrest pathways via repression of cdkn1a (show CDKN1A ELISA Kits) has a critical role during tumorigenesis in the skin.
This gene encodes a zinc finger protein involved in the regulation of c-myc. The symbol MIZ1 has also been associated with PIAS2 which is a different gene located on chromosome 18.
, E3 SUMO-protein ligase PIAS2
, androgen receptor-interacting protein 3
, msx-interacting zinc finger protein
, protein inhibitor of activated STAT X
, zinc finger, MIZ-type containing 4
, Myc-interacting Zn finger protein-1
, myc-interacting zinc finger protein 1
, zinc finger and BTB domain-containing protein 17
, zinc finger protein 151 (pHZ-67)
, zinc finger protein 60
, polyomavirus late initiator promoter-binding protein
, zinc finger protein 100
, zinc finger protein 151
, zinc finger protein Z13
, zinc finger protein Mfg-3