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anti-Human Angiotensin II/III Antibodies:
anti-Horse (Equine) Angiotensin II/III Antibodies:
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rs699 in the AGT gene and rs5186 in the ATR1 gene were not associated with the risk and clinical outcomes of IgAN.
The threonine variant of AGT (show AGXT Antibodies) M268T is a significant risk factor for abnormalities in specific white matter tracts and cognitive domains in healthy older adults.
Increased plasma renin, AT and VEGF might play a role in the onset or development of superficial infantile hemangiomas.
Blood pressure was significantly lower in angiotensinogen (show AGT Antibodies) knock-out mice compared to controls fed a normal or high sodium diet.
Detection of hANG(1-12) in hearts of homozygous transgenic rats expressing the hAGT gene suggests existence of non-renin (show REN Antibodies)-dependent enzyme mechanism capable of cleavage of human substrate.
AGT (show AGXT Antibodies)-H1 haplotype was identified as protective Factor for Essential Hypertension in Kazakhs in Xinjiang.
dominance of the aminopeptidase A (show ENPEP Antibodies)/Ang (2 (show ANGPT2 Antibodies)-10) and aminopeptidase A (show ENPEP Antibodies)/Ang III (show AGT Antibodies) (2-8) pathways in the metabolism of Ang I (show AGT Antibodies) (1-10) and Ang II (show AGT Antibodies) (1-8) over the ACE2 (show ACE2 Antibodies)/Ang (1 (show ANGPT1 Antibodies)-7) axis
The ACE2 (show ACE2 Antibodies)-Ang (1 (show ANGPT1 Antibodies)-7)-Mas (show MAS1 Antibodies) axis serves as an important signal pathway in endothelial cell protection in diabetic human arteries.
Urinary AGT (show AGXT Antibodies) could be a prognostic marker of renoprotective effects of alogliptin in patients with T2D
urinary AGT (show AGXT Antibodies)/protein ratio represents a novel specific marker of podocyte injury
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
alpha-1 antiproteinase, antitrypsin
, angiotensin I
, angiotensin II
, serine (or cysteine) proteinase inhibitor
, serpin A8