anti-Human Cardiotrophin 1 antibody for Functional Studies

Recommended Cardiotrophin 1 Antibody (supplied by: Log in to see )

Antigen
Cardiotrophin 1 (CTF1) Antibodies
  • CTF1
  • ct1
  • ct-1
  • ctf2
  • CT-1
  • CT1
  • cardiotrophin 1
  • cardiotrophin-1-like
  • CTF1
  • ctf1
  • Ctf1
  • LOC100736818
Reactivity
Human
134
47
37
3
3
2
2
2
1
Host
Rabbit
103
39
15
Clonality
Polyclonal
Conjugate
This Cardiotrophin 1 antibody is un-conjugated
15
8
6
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Functional Studies (Func), Western Blotting (WB)
133
67
28
16
15
13
11
6
4
2
2
2
2
1
1
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Catalog No. ABIN115990
$ 368.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN115989 EIA Func WB Rabbit Log in to see Polyclonal

General

Antigen Cardiotrophin 1 (CTF1) Antibodies
Reactivity Human
(134), (47), (37), (3), (3), (2), (2), (2), (1)
Host Rabbit
(103), (39), (15)
Clonality
Polyclonal
Conjugate This Cardiotrophin 1 antibody is un-conjugated
(15), (8), (6), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Functional Studies (Func), Western Blotting (WB)
(133), (67), (28), (16), (15), (13), (11), (6), (4), (2), (2), (2), (2), (1), (1)
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Product Details anti-Cardiotrophin 1 Antibody

Target Details Cardiotrophin 1 Application Details Handling Images
Specificity This antibody reacts with Human Cardiotrophin-1
Purification Affinity chromatography.
Immunogen Highly pure (>98%) recombinant hCardiotrophin-1.

Target Details Cardiotrophin 1

Product Details anti-Cardiotrophin 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Cardiotrophin-1 (CTF1 Antibody Abstract)
Background Cardiotrophin-1 (CT-1), a cardiac hypertrophic factor, is a 21.5 kDa protein member of the IL-6 cytokine family. CT-1 is associated with the pathophysiology of heart diseases, including hypertension, myocardial infarction, valvular heart disease, and congestive heart failure. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF kappa B DNA -binding activities. CT-1 is highly expressed in the heart, skeletal muscle, prostate and ovary and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine.Synonyms: CT-1, CTF1
Gene ID 1489
NCBI Accession NP_001136016
UniProt Q16619
Research Area Growth Factors
Pathways JAK-STAT Signaling

Application Details

Product Details anti-Cardiotrophin 1 Antibody Target Details Cardiotrophin 1 Handling Images back to top
Application Notes Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhCardiotrophin-1 (3 ng/mL), a concentration of 0.04-0.09 μg/mL of this antibody isrequired. ELISA: To detect hCardiotrophin-1 by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hCardiotrophin-1. Western Blot: To detect hCardiotrophin-1 by Western Blot analysis this antibody can beused at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hCardiotrophin-1 is 1.5-3.0 ng/lane, underreducing or non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Cardiotrophin 1 Antibody Target Details Cardiotrophin 1 Application Details Images back to top
Reconstitution Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
Buffer PBS, pH 7.2 without preservatives.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing. Centrifuge vial prior to opening!
Storage 4 °C/-20 °C
Storage Comment Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.