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Human CD25 ELISA Kit for Sandwich ELISA - ABIN1445998
Vorselaars, van Moorsel, Zanen, Ruven, Claessen, van Velzen-Blad, Grutters: ACE and sIL-2R correlate with lung function improvement in sarcoidosis during methotrexate therapy. in Respiratory medicine 2015
Show all 3 Pubmed References
Human CD25 ELISA Kit for Sandwich ELISA - ABIN2684679
May, Pemberton, Hart, McLeod, Wilcock, Doran: Use of whole blood for analysis of disease-associated biomarkers. in Analytical biochemistry 2013
Show all 4 Pubmed References
High IL2RA expression is associated with CRLF2 (show CRLF2 ELISA Kits)-rearranged acute lymphoblastic leukemia.
Inhibits CD25 translation through regulation of the LKB1 (show STK11 ELISA Kits)-AMPK (show PRKAA1 ELISA Kits)-mTOR (show FRAP1 ELISA Kits) pathway to suppress T cells.
Among patients with a low pretreatment sIL (show PMEL ELISA Kits)-2R level who exhibited a positive response to R-CHOP (show DDIT3 ELISA Kits), the posttreatment sIL (show PMEL ELISA Kits)-2R level may help to identify those with a poor prognosis.
The findings not only confirm the predictive power of CD25 expression for Philadelphia chromosome translocation (Ph)+ but also demonstrate that CD25 expression is associated with RD (a biomarker correlated with prognosis) in Ph- patients. The latter finding is likely associated with underlying molecular abnormalities, including Ph-like genotype.
Through GWAS, we found that emotion dysregulation is associated at genome-wide level significance in a sex-specific manner, with a SNP in IL2RA in men.
it has been shown that CD25 serves as a negative growth regulator of Chronic myeloid leukemia (show BCL11A ELISA Kits) leukemic stem cells.
study provides evidence that membrane-coated microvesicles released by apoptotic neutrophils suppress a subset of resting Th cells by downregulating IL-2 (show IL2 ELISA Kits) and IL-2R expression
In T1D, low IL-2 (show IL2 ELISA Kits) responsiveness was most pronounced in memory T effector cells. Reduced IL-2 (show IL2 ELISA Kits) responses in memory T effector cells were not rescued by resting, remained lower after activation and proliferation, and were absent in type 2 diabetes.
Decidual stromal cells affect IL-2 (show IL2 ELISA Kits) production and IL-2R expression and signaling.
The single nucleotide variant rs12722489 determines differential ERalpha (show ESR1 ELISA Kits) binding and enhancer properties of an IL2RA intronic region.
Data indicate that there was a differential transcription of 381 genes which changed greater than two fold in B1a of p40-/-IL-2Ralpha-/- mice.
At single cell level, IL-2 (show IL2 ELISA Kits) is binary (digital) and CD25 is graded expressed, whereas at population level both parameters show graded expression correlating with the antigen amount.
Results indicate that conjugated-interleukin-2 (IL2 (show IL2 ELISA Kits)) protein derived from NKTR (show NKTR ELISA Kits)-214 occupy interleukin-2 (IL2 (show IL2 ELISA Kits)) receptor complex (IL2Ralphabetagamma) to a greater extent compared to free-IL2 (show IL2 ELISA Kits) protein.
CDK6 (show CDK6 ELISA Kits)-mediated suppression of CD25 is required for initiation of T-ALL by activated Notch1 (show NOTCH1 ELISA Kits). . Pharmacologic inhibition of CDK6 (show CDK6 ELISA Kits) kinase induces CD25 and RUNX1 (show RUNX1 ELISA Kits) expression, cell cycle arrest and apoptosis in mouse and human T-ALL.
Combination with anti-programmed cell death protein-1 (PD-1 (show PDCD1 ELISA Kits)) antibodies promoted complete tumor rejection (show SLC35A4 ELISA Kits), indicating the relevance of CD25 antigen as a therapeutic target and promising substrate for future combination approaches in immune-oncology.
Intratesticular inoculation with donor antigens promotes long-term skin allograft survival induced by conventional costimulatory blockade via the induction of both CD8 (show CD8A ELISA Kits) + CD122 (show IL2RB ELISA Kits)+ and CD4 (show CD4 ELISA Kits) + CD25+ Treg cells.
glucosamine interferes with N-glycosylation of CD25, and thereby attenuates IL-2 (show IL2 ELISA Kits) downstream signaling
Expansion of CD25-expressing innate lymhpoid cells by IL-2 (show IL2 ELISA Kits)/anti-IL-2 (show IL2 ELISA Kits) complexes leads to a reduction in very low-density lipoprotein cholesterol and atherosclerosis.
our results identify IL-7 (show IL7 ELISA Kits) as a necessary factor contributing to sustained CD25 expression at Treg surface in vivo thereby affecting their ability to efficiently react to IL-2 (show IL2 ELISA Kits).
Data indicate that the deletion of interferon-gamma (IFN-gamma (show IFNG ELISA Kits)) in the CD25 knockout (KO) mice delays glandular destruction and preserves glandular function.
IL2 (show IL2 ELISA Kits)-R was equally expressed in interfollicular tissue and in follicles, whereas in moderate and severe cases of postweaning multisystemic wasting syndrome, it was detected in interfollicular remnants only
The appearance of CD25 after activation of porcine dendritic cells, is reported.
Differential expression of CD25 and IDO (show IDO1 ELISA Kits) mRNA with high and low virulence bovine viral diarrhea virus might reflect temporal differences in transcription during the immune response elicited by these viral strains.
Increase of CD25 expression on bovine neutrophils correlates with mastitis severity in post-partum and early lactating dairy cows.
The PGE2-mediated down-regulation of CD25 expression on T cells is mediated via the EP4 (show PTGER4 ELISA Kits) receptor, although selective activation of the EP2 receptor up-regulates the CD25 expression on these cells.
There is a positive correlation between the intensity of CD25 expression and the expression of the transcription Foxp3 (show FOXP3 ELISA Kits) factor in bovine CD8 (show CD8A ELISA Kits)(+) cells.
determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25, CD44 (show CD44 ELISA Kits), and CD62L (show SELL ELISA Kits) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.
Pretreatment of neonatal PBMC with IL-1beta (show IL1B ELISA Kits), TNF-alpha (show TNF ELISA Kits) or IFN-gamma (show IFNG ELISA Kits) promotes mitogenic response to ConA through up-regulating the production of IL-2 (show IL2 ELISA Kits) and the expression of the mature IL-2 (show IL2 ELISA Kits) receptor.
These findings revealed that despite the existence of a distinct bovine CD4 (show CD4 ELISA Kits)(+)CD25(high) T cell population, which showed Foxp3 (show FOXP3 ELISA Kits) transcription/expression, natural regulatory activity did not reside in this cell population
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
IL-2 receptor subunit alpha
, IL-2R subunit alpha
, TAC antigen
, interleukin-2 receptor subunit alpha
, IL-2 receptor alpha subunit
, interleukin 2 receptor, alpha chain
, interleukin-2 receptor alpha chain
, IL-2 alpha receptor
, IL2 receptor alpha
, interleukin-2 alpha receptor
, interleukin 2 receptor alpha chain
, interleukin-2 receptor alpha subunit
, IL-2 Receptor alpha chain
, interleukin 2 receptor, alpha
, IL-2R alpha chain
, p55 chain
, IL-2R alpha
, cytokine receptor
, CD25 antigen