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anti-Human CSF2RB antibody for Enzyme Immunoassay

Recommended CSF2RB Antibody (supplied by: Log in to see )

Antigen
Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage) (CSF2RB) Antibodies
  • AI848964
  • AIC2B
  • Bc
  • CD131
  • cd131
  • CDw131
  • cdw131
  • CSF2RB
  • Csf2rb1
  • Csfgmrb
  • il-3rbc
  • Il3r
  • Il3rb
  • IL3RB
  • il3rb
  • Il3rb1
  • Il5rb
  • il5rb
  • IL5RB
  • SMDP5
Epitope
pTyr766
14
12
11
8
6
6
5
5
2
1
1
1
1
1
1
Reactivity
Human
93
7
6
2
Host
Rabbit
64
29
1
Clonality
Polyclonal
Conjugate
This CSF2RB antibody is un-conjugated
9
8
6
5
5
5
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
64
48
16
15
7
7
5
1
1
1
1
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Catalog No. ABIN358147
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008833851 ABIN358962 EIA WB Rabbit Ig C-Term Log in to see Polyclonal 3

Top referenced anti-CSF2RB antibody for Enzyme Immunoassay

Similar anti-CSF2RB Antibodies

Application / Reactivity Human
Dot Blot (DB) 7 Antibodies
ELISA 48 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 17 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 1 Antibodies
Immunohistochemistry (IHC) 17 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Immunoprecipitation (IP) 5 Antibodies
Western Blotting (WB) 65 Antibodies

General

Antigen Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage) (CSF2RB) Antibodies
Epitope pTyr766
(14), (12), (11), (8), (6), (6), (5), (5), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(93), (7), (6), (2)
Host Rabbit
(64), (29), (1)
Clonality
Polyclonal
Conjugate This CSF2RB antibody is un-conjugated
(9), (8), (6), (5), (5), (5)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(64), (48), (16), (15), (7), (7), (5), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-CSF2RB Antibody

Target Details CSF2RB Application Details Handling References for anti-CSF2RB Antibody (ABIN358147) Images
Specificity This antibody detects IL3R pTyr766.
Purification Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y766 of human IL3R.
Isotype Ig

Target Details CSF2RB

Product Details anti-CSF2RB Antibody Application Details Handling References for anti-CSF2RB Antibody (ABIN358147) Images back to top
Antigen
Alternative Name CD131 / CSF2RB (CSF2RB Antibody Abstract)
Background IL3R (also known as CSF2RB) is a common beta chain of the high affinity receptor for IL-3, IL-5 and GM-CSF. Defective IL3R has been reported to be associated with protein alveolar proteinosis (PAP). PAP is an autosomal recessive fatal respiratory disease.Synonyms: Cytokine receptor common subunit beta, GM-CSF-RB, GM-CSF/IL-3/IL-5 receptor common beta-chain, IL3RB, IL5RB
Molecular Weight 97336 Da
Gene ID 1439, 9606
UniProt P32927
Pathways JAK-STAT Signaling

Application Details

Product Details anti-CSF2RB Antibody Target Details CSF2RB Handling References for anti-CSF2RB Antibody (ABIN358147) Images back to top
Application Notes ELISA: 1/1,000. Dot Blot: 1/500. Western Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CSF2RB Antibody Target Details CSF2RB Application Details References for anti-CSF2RB Antibody (ABIN358147) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-CSF2RB Antibody (ABIN358147)

Product Details anti-CSF2RB Antibody Target Details CSF2RB Application Details Handling Images back to top
Background publications

Murphy, Ford, Olsen, Gustin, Jeffrey, Ollis, Young: "Interleukin-3 binding to the murine betaIL-3 and human betac receptors involves functional epitopes formed by domains 1 and 4 of different protein chains." in: The Journal of biological chemistry, Vol. 279, Issue 25, pp. 26500-8, 2004

McClure, Hercus, Cambareri, Woodcock, Bagley, Howlett, Lopez: "Molecular assembly of the ternary granulocyte-macrophage colony-stimulating factor receptor complex." in: Blood, Vol. 101, Issue 4, pp. 1308-15, 2003

Scibek, Evergren, Zahn, Canziani, Van Ryk, Chaiken: "Biosensor analysis of dynamics of interleukin 5 receptor subunit beta(c) interaction with IL5:IL5R(alpha) complexes." in: Analytical biochemistry, Vol. 307, Issue 2, pp. 258-65, 2002

Blake, Jenkins, DAndrea, Gonda: "Functional cross-talk between cytokine receptors revealed by activating mutations in the extracellular domain of the beta-subunit of the GM-CSF receptor." in: Journal of leukocyte biology, Vol. 72, Issue 6, pp. 1246-55, 2002

Evans, Ariffin, Pierce, Whetton: "Identification of primary structural features that define the differential actions of IL-3 and GM-CSF receptors." in: Blood, Vol. 100, Issue 9, pp. 3164-74, 2002

Images

Product Details anti-CSF2RB Antibody Target Details CSF2RB Application Details Handling References for anti-CSF2RB Antibody (ABIN358147) back to top
Supplier Images
 image for anti-CSF2RB antibody (Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage)) (pTyr766) (ABIN358147) anti-Colony Stimulating Factor 2 Receptor, Beta, Low-Affinity (Granulocyte-Macrophage) (CSF2RB) (pTyr766) antibody