anti-Mouse (Murine) EPO antibody for Flow Cytometry

Recommended EPO Antibody (supplied by: Log in to see )

Antigen
Erythropoietin (EPO) Antibodies
  • EPO
  • EP
  • MVCD2
  • erythropoietin
  • EPO
  • epo
  • Epo
Reactivity
Mouse (Murine)
340
75
43
7
4
3
3
2
2
1
1
1
1
1
1
Host
Rat
192
172
14
5
3
1
Clonality
Monoclonal
Conjugate
This EPO antibody is un-conjugated
28
21
16
10
6
6
6
5
5
5
5
5
5
5
5
4
4
4
4
3
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
250
216
67
60
56
51
30
13
11
10
7
6
4
3
2
2
2
2
2
1
1
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Catalog No. ABIN2664956
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General

Antigen Erythropoietin (EPO) Antibodies
Reactivity Mouse (Murine)
(340), (75), (43), (7), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rat
(192), (172), (14), (5), (3), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This EPO antibody is un-conjugated
(28), (21), (16), (10), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS)
(250), (216), (67), (60), (56), (51), (30), (13), (11), (10), (7), (6), (4), (3), (2), (2), (2), (2), (2), (1), (1)
Pubmed 8 references available
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Product Details anti-EPO Antibody

Target Details EPO Application Details Handling ProductDetails: References for anti-EPO antibody (ABIN2664956) Images
Purification The antibody was purified by affinity chromatography.
Clone M029F6
Isotype IgG2b

Target Details EPO

Product Details anti-EPO Antibody Application Details Handling ProductDetails: References for anti-EPO antibody (ABIN2664956) Images back to top
Antigen
Alternative Name EPO (EPO Antibody Abstract)
Background EPO is a glycoprotein that is glycosylated up to 40-60 % , which causes its molecular weight to vary from 30-34 kD depending on the carbohydrate percentage. Hypoxia induces erythropoiesis, and hypoxia inducible factor (HIF) is directly involved in EPO expression. HIF-Prolyl hydroxylase (HIF-PH) is a sensor of levels of iron, oxygen, and metabolic activity. High levels of HIF protein induces EPO production in the kidneys and liver, and mobilizes iron to support erythropoiesis. EPO has been used in the treatment of anemia associated with chronic kidney disease, treatment of cancer patients on chemotherapy, and antiviral HIV therapy.
Research Area Cancer, Organogenesis, Hematopoietic Progenitors, Angiogenesis
Pathways JAK-STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity

Application Details

Product Details anti-EPO Antibody Target Details EPO Handling ProductDetails: References for anti-EPO antibody (ABIN2664956) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-EPO Antibody Target Details EPO Application Details ProductDetails: References for anti-EPO antibody (ABIN2664956) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

ProductDetails: References for anti-EPO antibody (ABIN2664956)

Product Details anti-EPO Antibody Target Details EPO Application Details Handling Images back to top
Background publications

Alnaeeli, Wang, Piknova, Rogers, Li, Noguchi: "Erythropoietin in brain development and beyond." in: Anatomy research international, Vol. 2012, pp. 953264, 2012

Kassouf, Hughes, Taylor, McGowan, Soneji, Green, Vyas, Porcher: "Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells." in: Genome research, Vol. 20, Issue 8, pp. 1064-83, 2010

Paliege, Rosenberger, Bondke, Sciesielski, Shina, Heyman, Flippin, Arend, Klaus, Bachmann: "Hypoxia-inducible factor-2alpha-expressing interstitial fibroblasts are the only renal cells that express erythropoietin under hypoxia-inducible factor stabilization." in: Kidney international, Vol. 77, Issue 4, pp. 312-8, 2010

Sinclair, Coxon, McCaffery, Kaufman, Paweletz, Liu, Busse, Swift, Elliott, Begley: "Functional erythropoietin receptor is undetectable in endothelial, cardiac, neuronal, and renal cells." in: Blood, Vol. 115, Issue 21, pp. 4264-72, 2010

Snow, Orkin: "Translational isoforms of FOG1 regulate GATA1-interacting complexes." in: The Journal of biological chemistry, Vol. 284, Issue 43, pp. 29310-9, 2009

Chin, Yu, Beleslin-Cokic, Liu, Shen, Mohrenweiser, Noguchi: "Production and processing of erythropoietin receptor transcripts in brain." in: Brain research. Molecular brain research, Vol. 81, Issue 1-2, pp. 29-42, 2000

Shoemaker, Mitsock: "Murine erythropoietin gene: cloning, expression, and human gene homology." in: Molecular and cellular biology, Vol. 6, Issue 3, pp. 849-58, 1986

McDonald, Lin, Goldwasser: "Cloning, sequencing, and evolutionary analysis of the mouse erythropoietin gene." in: Molecular and cellular biology, Vol. 6, Issue 3, pp. 842-8, 1986

Images

Product Details anti-EPO Antibody Target Details EPO Application Details Handling ProductDetails: References for anti-EPO antibody (ABIN2664956) back to top
Supplier Images
Western Blotting (WB) image for anti-Erythropoietin (EPO) antibody (ABIN2664956) anti-Erythropoietin (EPO) antibody