anti-Human EPOR antibody for Enzyme Immunoassay

Recommended EPOR Antibody (supplied by: Log in to see )

Antigen
Erythropoietin Receptor (EPOR) Antibodies
  • EPOR
  • epor
  • EPO-R
  • erythropoietin receptor
  • Erythropoietin receptor
  • erythropoietin receptor homologue
  • erythropoietin receptor-like
  • EPOR
  • epor
  • Epor
  • LOC100355350
Epitope
AA 328-357, Middle Region
25
17
16
15
11
10
10
7
7
6
6
6
5
5
5
5
5
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
202
80
73
7
4
3
3
2
2
2
1
1
1
Host
Rabbit
141
61
13
1
Clonality
Polyclonal
Conjugate
This EPOR antibody is un-conjugated
13
10
9
6
6
4
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
157
82
53
49
40
35
32
16
13
7
4
2
2
2
1
1
1
1
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Catalog No. ABIN952118
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5566826 EIA RIA Biotin Rabbit AA 25-250 Log in to see Polyclonal
1 ABIN5541017 EIA FACS WB Rat IgG2b Cytoplasmic Domain Log in to see BCO-3H2
1 ABIN5566824 EIA RIA Rabbit AA 25-250 Log in to see Polyclonal
1 ABIN5541016 EIA FACS IP Mouse IgG1 Log in to see VP-2E8

General

Antigen Erythropoietin Receptor (EPOR) Antibodies
Epitope AA 328-357, Middle Region
(25), (17), (16), (15), (11), (10), (10), (7), (7), (6), (6), (6), (5), (5), (5), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(202), (80), (73), (7), (4), (3), (3), (2), (2), (2), (1), (1), (1)
Host Rabbit
(141), (61), (13), (1)
Clonality
Polyclonal
Conjugate This EPOR antibody is un-conjugated
(13), (10), (9), (6), (6), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
(157), (82), (53), (49), (40), (35), (32), (16), (13), (7), (4), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-EPOR Antibody

Target Details EPOR Application Details Handling References for anti-EPOR antibody (ABIN952118) Images
Specificity This antibody recognizes Human Erythropoietin receptor (Center).
Purification Affinity Chromatography on Protein A
Immunogen KLH conjugated synthetic peptide between 328-357 amino acids from the Central region of Human Erythropoietin receptor Genename: EPOR
Isotype Ig

Target Details EPOR

Product Details anti-EPOR Antibody Application Details Handling References for anti-EPOR antibody (ABIN952118) Images back to top
Antigen
Alternative Name Erythropoietin Receptor (EPOR Antibody Abstract)
Background This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.Synonyms: EPO-R, EPOR
Molecular Weight 55065 Da
Gene ID 2057
NCBI Accession NP_000112
Research Area Hormones, Receptors
Pathways JAK-STAT Signaling

Application Details

Product Details anti-EPOR Antibody Target Details EPOR Handling References for anti-EPOR antibody (ABIN952118) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-EPOR Antibody Target Details EPOR Application Details References for anti-EPOR antibody (ABIN952118) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-EPOR antibody (ABIN952118)

Product Details anti-EPOR Antibody Target Details EPOR Application Details Handling Images back to top
Background publications

Lim, Ketchem, Borges, Carabeo, Carter, Hoover, Hu, Wittekind, Zhou, Mehlin: "A diversity of antibody epitopes can induce signaling through the erythropoietin receptor." in: Biochemistry, Vol. 49, Issue 18, pp. 3797-804, 2010

Images

Product Details anti-EPOR Antibody Target Details EPOR Application Details Handling References for anti-EPOR antibody (ABIN952118) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Erythropoietin Receptor (EPOR) (AA 328-357), (Middle Region) antibody (ABIN952118) Flow cytometric analysis of Hela cells using Erythropoietin receptor  Antibody  (righ...
Western Blotting (WB) image for anti-Erythropoietin Receptor (EPOR) (AA 328-357), (Middle Region) antibody (ABIN952118) Western blot analysis of Erythropoietin receptor  Antibody  in NCI-H460 cell line lys...