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|Application / Reactivity||Mouse (Murine)||Human|
|Biochemical Assay (BCA)||2 Antibodies||2 Antibodies|
|ELISA||45 Antibodies||97 Antibodies|
|Enzyme Immunoassay (EIA)||2 Antibodies||4 Antibodies|
|Flow Cytometry (FACS)||4 Antibodies||18 Antibodies|
|Functional Studies (Func)||1 Antibodies|
|Immunocytochemistry (ICC)||7 Antibodies|
|Immunofluorescence (IF)||4 Antibodies|
|Immunohistochemistry (IHC)||19 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||3 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||15 Antibodies|
|Immunoprecipitation (IP)||12 Antibodies|
|Western Blotting (WB)||78 Antibodies|
|Antigen||FYN Oncogene Related To SRC, FGR, YES (FYN) Antibodies|
|Reactivity||Human, Mouse (Murine) Alternatives|
|Conjugate||This FYN antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|4 references available|
|Supplier||Log in to see|
Product Details anti-FYN AntibodyTarget Details FYN Application Details Handling References for anti-FYN Antibody (ABIN359983) Images
|Specificity||This antibody detects FYN at N-term.|
|Purification||Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human FYN.|
Target Details FYNProduct Details anti-FYN Antibody Application Details Handling References for anti-FYN Antibody (ABIN359983) Images back to top
|Alternative Name||FYN (FYN Antibody Abstract)|
|Background||FYN is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein.Synonyms: Proto-oncogene tyrosine-protein kinase Fyn, Protooncogene Syn, SLK, p59-Fyn|
|Molecular Weight||60630 Da|
|Gene ID||2534, 9606|
|Pathways||JAK-STAT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway|
Application DetailsProduct Details anti-FYN Antibody Target Details FYN Handling References for anti-FYN Antibody (ABIN359983) Images back to top
ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-FYN Antibody Target Details FYN Application Details References for anti-FYN Antibody (ABIN359983) Images back to top
|Buffer||PBS with 0.09 % (W/V) Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-FYN Antibody (ABIN359983)Product Details anti-FYN Antibody Target Details FYN Application Details Handling Images back to top
Taniguchi, Liu, Nakazawa et al.: "p250GAP, a neural RhoGAP protein, is associated with and phosphorylated by Fyn." in: Biochemical and biophysical research communications, Vol. 306, Issue 1, pp. 151-5, 2003 (PubMed).
Chan, Lanyi, Song et al.: "SAP couples Fyn to SLAM immune receptors." in: Nature cell biology, Vol. 5, Issue 2, pp. 155-60, 2003 (PubMed).
Freund, Kühne, Yang et al.: "Dynamic interaction of CD2 with the GYF and the SH3 domain of compartmentalized effector molecules." in: The EMBO journal, Vol. 21, Issue 22, pp. 5985-95, 2002 (PubMed).
Goldsmith, Hall, Atkinson: "Identification of an alternatively spliced isoform of the fyn tyrosine kinase." in: Biochemical and biophysical research communications, Vol. 298, Issue 4, pp. 501-4, 2002 (PubMed).
ImagesProduct Details anti-FYN Antibody Target Details FYN Application Details Handling References for anti-FYN Antibody (ABIN359983) back to top