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these results suggest that the activation of 5-HT1D receptors selectively enhanced IA via the Gbetagamma of the Go-protein, PKA, and the sequential B-Raf (show SNRPE Proteins)-dependent p38 MAPK (show MAPK14 Proteins) signaling cascade.
5-hydroxytryptamine (serotonin) receptor 1D is a novel marker for gamma motor neurons and that the 5-ht1d receptor is important to receive and relay accurate sensory information in developing and mature spinal cord motor circuits.
5-Hydroxytryptamine(1B/1D) receptors inhibit capsaicin-induced c-fos immunoreactivity within mouse trigeminal nucleus caudalis.
PrPC is a modulator of 5-HT receptor coupling to G-proteins and contributes to the homeostasis of serotonergic neurons
5-HT2B (show HTR2B Proteins) and 1D autoreceptors may play a role in the maintenance of neuron- and neurotransmitter-associated functions.
Data show that 5-hydroxytryptamine receptor (5-HT1DR) played an important role in cell invasion via Axin1 (show AXIN1 Proteins)/beta-catenin (show CTNNB1 Proteins)/matrix metalloproteinase 7 (MMP-7 (show MMP7 Proteins)) pathway.
results suggest that 5-HT signaling participates in regulation of overall islet hormone secretion in non- diabetic individuals and over-expression of HTR1D and HTR2A may either contribute to islet dysfunction in T2D
Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.
5-HT1B- and 5-HT1D-mediated signaling play an important role in the regulation of the proliferative and invasive phenotype of pancreatic cancer cells.
study identified the presence of genetic association at chromosome 1p36 with migraine with aura (show AURKA Proteins) (P=0.045, Bonferroni corrected): the locus encoding the 5HT (show DDC Proteins)(1D) receptor gene
This study reveals sex-specific alterations in gene expression of the pre-synaptic 5-HT1D autoreceptors and 5-HT (show DDC Proteins)-related transcription factors, NUDR (show DEAF1 Proteins) and REST, in dorsal raphe neurons of women with major depression disorder.
Polymorphisms in the serotonin 5-HT1D receptor gene are preferentially transmitted in attention-deficit hyperactivity disorder in Chinese Han subjects.
The density of 5HT (show DDC Proteins)(1D)R was significantly more in tissues known to produce migraine-like pain. 5HT (show DDC Proteins)(1D)R-like immunoreactivity was restricted to neuronal fibres, colocalizing with calcitonin gene-related peptide (show CALCA Proteins) & tyrosine hydroxylase (show TH Proteins) positive fibres.
Cell adhesion modulates 5-HT(1D) and P2Y (show P2RY1 Proteins) receptor signal trafficking differentially in LTK (show LTK Proteins)-8 cells.
G-protein coupled receptor for serotonin\; found in nociceptors throughout the body
, 5-hydroxytryptamine (serotonin) receptor 1D beta
, 5-hydroxytryptamine receptor 1D
, G-protein coupled receptor 14
, serotonin receptor 1D
, serotonin 1D alpha receptor
, 5 - Hydroxytryptamine (serotonin) receptor 1D
, 5-HT1D receptor
, 5-HT1D alpha receptor