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anti-Human IFNA2 antibody for Functional Studies

Recommended IFNA2 Antibody (supplied by: Log in to see )

Antigen
Interferon, alpha 2 (IFNA2) Antibodies
  • Ifa2
  • IFN-a
  • IFN-alphaA
  • IFNA
  • IFNA2B
  • INFA2
Reactivity
Human
101
7
4
Host
Mouse
64
38
2
Clonality
Monoclonal
Conjugate
This IFNA2 antibody is un-conjugated
5
3
3
Application
Functional Studies (Func), Enzyme Immunoassay (EIA), Neutralization (Neut), Western Blotting (WB)
67
66
8
7
6
5
4
4
3
2
2
2
1
1
1
1
1
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Catalog No. ABIN1107640
$ 357.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00087742554 ABIN1107639 Func EIA Neut WB Mouse IgG1 Log in to see N39 2
0.00087742554 ABIN189774 Func IHC (fro) IP ELISA WB Mouse IgG1 Log in to see MMHA-1

Top referenced anti-IFNA2 antibody for Functional Studies

Similar anti-IFNA2 Antibodies

Application / Reactivity Human
Blocking Reagent (BR) 2 Antibodies
ELISA 65 Antibodies
Enzyme Immunoassay (EIA) 3 Antibodies
Flow Cytometry (FACS) 2 Antibodies
Functional Studies (Func) 3 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 4 Antibodies
Immunofluorescence (IF) 6 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 1 Antibodies
Immunohistochemistry (IHC) 7 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 1 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 1 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Immunoprecipitation (IP) 8 Antibodies
Neutralization (Neut) 2 Antibodies
Western Blotting (WB) 67 Antibodies

General

Antigen Interferon, alpha 2 (IFNA2) Antibodies
Reactivity Human
(101), (7), (4)
Host Mouse
(64), (38), (2)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IFNA2 antibody is un-conjugated
(5), (3), (3)
Application Functional Studies (Func), Enzyme Immunoassay (EIA), Neutralization (Neut), Western Blotting (WB)
(67), (66), (8), (7), (6), (5), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-IFNA2 Antibody

Target Details IFNA2 Application Details Handling References for anti-IFNA2 Antibody (ABIN1107640) Images
Specificity N27 is specific for INFalpha(II) and does not crossreact with INFalpha(I).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Purified
Immunogen A BALB/c mouse was immunized with E-coli derived, purified recombinant IFN-alpha 2c and spleen cells were fused with mouse myeloma cells NS1.
Clone N27
Isotype IgG1

Target Details IFNA2

Product Details anti-IFNA2 Antibody Application Details Handling References for anti-IFNA2 Antibody (ABIN1107640) Images back to top
Antigen
Alternative Name IFNA2 / Interferon alpha-2 (IFNA2 Antibody Abstract)
Background The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNalpha family has pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNalpha are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNalpha include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNalpha are now known and seem to be expressed on most cell types.Synonyms: IFN-alpha 2, Interferon alpha-A, LeIF A
Gene ID 3440
NCBI Accession NP_000596
UniProt P01563
Pathways JAK-STAT Signaling

Application Details

Product Details anti-IFNA2 Antibody Target Details IFNA2 Handling References for anti-IFNA2 Antibody (ABIN1107640) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IFNA2 Antibody Target Details IFNA2 Application Details References for anti-IFNA2 Antibody (ABIN1107640) Images back to top
Concentration 0,1 mg/mL
Buffer PBS, 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

References for anti-IFNA2 Antibody (ABIN1107640)

Product Details anti-IFNA2 Antibody Target Details IFNA2 Application Details Handling Images back to top
Background publications

Kontsek, Borecký, Zavyalov, Maiorov: "Peptide-mapping of three neutralizing epitopes into predicted biologically active sites of human interferon-alpha 2." in: Immunology letters, Vol. 35, Issue 3, pp. 281-4, 1993

Kontsek, Borecky, Kontsekova, Macikova, Kolcunova, Novak, Krchnak: "Mapping of two immunodominant structures on human interferon alpha 2c and their role in binding to cells." in: Molecular immunology, Vol. 28, Issue 11, pp. 1289-97, 1992